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Method and means for detecting and treating disorders in the blood coagulation cascade

  • US 6,083,905 A
  • Filed: 01/22/1997
  • Issued: 07/04/2000
  • Est. Priority Date: 04/22/1994
  • Status: Expired due to Fees
First Claim
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1. A pharmaceutical composition comprising a blood coagulation Factor V which carries a substitution mutation of an arginine residue in at least one position selected from the group consisting of residues 306, 506 and 1765:

  • wherein the pharmaceutical composition is resistant against activated protein C.

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