System for treating congestive heart failure

• US 6,086,527 A
• Filed: 04/02/1998
• Issued: 07/11/2000
• Est. Priority Date: 04/02/1998
• Status: Expired due to Fees

• Current Assignee: Boston Scientific Scimed, Inc. (Boston Scientific Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Talpade, Dnyanesh
• Primary Examiner(s): Kamm, William E.
• Assistant Examiner(s): Evanisko, George R.
• Application Number:
  US09/054,214
• Time in Patent Office: 831 Days
• Field of Search: 600/16-18, 623/3, 604/101
• US Class Current: 600/18
• CPC Class Codes: A61M 2205/33 Controlling, regulating or measuring
• CPC Class Codes: A61M 2205/3303 Using a biosensor
• CPC Class Codes: A61M 2205/3334 Measuring or controlling the flow rate
• CPC Class Codes: A61M 60/148 in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
• CPC Class Codes: A61M 60/232 Centrifugal pumps
• CPC Class Codes: A61M 60/274 the inlet and outlet being the same, e.g. para-aortic counter-pulsation blood pumps
• CPC Class Codes: A61M 60/408 the force acting on the blood contacting member being mechanical, e.g. transmitted by a shaft or cable
• CPC Class Codes: A61M 60/523 using blood flow data, e.g. from blood flow transducers
• CPC Class Codes: A61M 60/546 of blood flow, e.g. by adapting rotor speed
• CPC Class Codes: A61M 60/824 Hydrodynamic or fluid film bearings
• CPC Class Codes: A61M 60/833 Occluders for preventing backflow

Abstract

A system is provided for regulating blood flow to a portion of the vasculature, such as the renal system, in order to treat heart disease. A regulator maintains blood flow so as to control physiological feedback responses in order to relieve overload conditions on the heart.

Claims

1. A method of treating heart disease in a mammal having a coronary system including a heart, an ascending aorta, and a descending aorta, a renal system including renal arteries, and a physiological feedback system including baroreceptors and a renal response system controlling the heart, the method comprising:

providing a first regulator disposed in the descending aorta proximate the renal arteries and a second regulator disposed in the ascending aorta; and

regulating flow of blood to the renal arteries from the descending aorta with the first regulator and regulating flow of blood in the ascending aorta to affect the physiological feedback system such that heart congestion is reduced.

2. The method of claim 1 wherein providing the first regulator comprises:

providing a first expandable member;

providing a second expandable member;

disposing the first expandable member in the descending aorta upstream of the renal arteries; and

disposing the second expandable member in the descending aorta downstream of the renal arteries, wherein the first and second expandable members are expandable to have a dimension sufficient to substantially occlude the descending aorta.

3. The method of claim 2 and further comprising:

controlling expansion of the first and second expandable members to periodically increase blood flow to the renal arteries in excess of naturally occurring blood flow.

4. The method of claim 3 wherein expanding the first and second expandable members comprises:

contracting the first expandable member;

expanding the second expandable member to allow blood to pool in the descending aorta proximate the renal arteries; and

then expanding the first expandable member to increase blood pressure and blood flow into the renal arteries.

5. The method of claim 4 and further comprising:

contracting the second expandable member after the first expandable member has been expanded.

6. The method of claim 4 and further comprising:

contracting the second expandable member as the first expandable member is being expanded.

7. The method of claim 4 wherein expanding the first expandable member and expanding the second expandable member comprises:

controlling expansion of the first and second expandable members based on a sinus rhythm of the heart.

8. The method of claim 2 wherein providing the second regulator comprises:

providing a third expandable member;

providing a fourth expandable member;

disposing the third expandable member in the aorta upstream of a baroreceptor proximate a heart; and

disposing the fourth expandable member in the aorta downstream of the baroreceptor proximate the heart, wherein the third and fourth expandable members are expandable to have a dimension sufficient to substantially occlude the aorta.

9. The method of claim 8 and further comprising:

controlling expansion of the third and fourth expandable members to periodically decrease blood flow to the renal arteries in excess of naturally occurring blood flow.

10. The method of claim 1 wherein regulating flow of blood with the first regulator comprises:

increasing blood flow velocity to the renal arteries with the first regulator.

11. The method of claim 1 wherein regulating flow with the second regulator comprises:

decreasing blood flow velocity to the renal system with the second regulator.

12. The method of claim 1 wherein providing the second regulator comprises:

providing a first expandable member;

providing a second expandable member;

disposing the first expandable member in the aorta upstream of a baroreceptor proximate a heart; and

disposing the second expandable member in the aorta downstream of the baroreceptor proximate the heart, wherein the first and second expandable members are expandable to have a dimension sufficient to substantially occlude the aorta.

13. The method of claim 12 and further comprising:

controlling expansion of the first and second expandable members to periodically decrease blood flow to the renal arteries in excess of naturally occurring blood flow.

14. The method of claim 1 wherein providing the first regulator comprises:

providing a pumping mechanism;

disposing the pumping mechanism in the descending aorta upstream of the renal arteries; and

operating the pumping mechanism to selectively increase blood flow in the renal system above naturally occurring blood flow.

15. The method of claim 14 wherein providing the second regulator comprises:

providing a second pumping mechanism;

disposing the second pumping mechanism in the ascending aorta proximate a baroreceptor proximate the heart; and

operating the pumping mechanism to selectively decrease blood pressure at the baroreceptor below naturally occurring blood pressure.

16. The method of claim 15 wherein the first and second pumping mechanisms each comprise expandable members.

17. The method of claim 16 wherein the first and second pumping mechanisms each comprise pumps having a passageway through which blood can flow.