Medical devices made from improved polymer blends

• US 6,093,463 A
• Filed: 03/20/1998
• Issued: 07/25/2000
• Est. Priority Date: 12/12/1997
• Status: Expired due to Term

• Current Assignee: Avantec Vascular Corporation
• Original Assignee: Intella Interventional Systems, Inc.
• Inventors: Thakrar, Ashok R.
• Primary Examiner(s): Robinson, Ellis
• Assistant Examiner(s): FIGUEROA, JOHN J
• Application Number:
  US09/045,483
• Time in Patent Office: 858 Days
• Field of Search: 428/35.7, 428/36.9, 428/36.91, 428/36.92, 604/95, 604/96, 604/97, 604/101, 604/102, 604/103, 604/93, 604/915, 604/919, 524/159, 524/288, 524/289, 524/500, 524/524
• US Class Current: 428/36.9
• CPC Class Codes: A61L 29/049 Mixtures of macromolecular compounds
• CPC Class Codes: A61L 29/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
• CPC Class Codes: A61L 29/141 Plasticizers
• CPC Class Codes: C08L 59/02 Polyacetals containing polyoxymethylene sequences only
• CPC Class Codes: C08L 73/00 Compositions of macromolecular compounds obtained by reactions forming a linkage containing oxygen or oxygen and carbon in the main chain, not provided for in groups C08L59/00 - C08L71/00; Compositions of derivatives of such polymers
• CPC Class Codes: Y10T 428/139 Open-ended, self-supporting conduit, cylinder, or tube-type article
• CPC Class Codes: Y10T 428/1393 Multilayer [continuous layer]
• CPC Class Codes: Y10T 428/1397 Single layer [continuous layer]
• CPC Class Codes: Y10T 428/31942 Of aldehyde or ketone condensation product

Abstract

Disclosed are medical devices including a composition that includes an aliphatic polyketone and a thermoplastic polymer.

Claims

1. An intraluminal balloon that comprises a composition comprising

(a) at least one aliphatic polyketone;

and

(b) a thermoplastic polymer;

wherein the at least one aliphatic polyketone is derived from monomers consisting of carbon monoxide and alpha olefins.

2. The intraluminal balloon of claim 1, wherein the at least one aliphatic polyketone is present in an amount of about 5 to about 95 weight percent, based on the total weight of the composition.

3. The intraluminal balloon of claim 1, wherein the thermoplastic polymer is present in an amount of about 5 to about 95 weight percent, based on the total weight of the composition.

4. The intraluminal balloon of claim 1, wherein the thermoplastic polymer comprises polyamide, polyester, polyether-blockamide, polyurethane, polyethylene, polyacetal, polyacrylonitrile, or polyvinylidene fluoride.

5. The intraluminal balloon of claim 1, wherein the thermoplastic polymer comprises polyamide.

6. The intraluminal balloon of claim 1, further comprising a plasticizer.

15. The intraluminal balloon of claim 1 having a wall comprising a balloon wall material, wherein the balloon wall material is perforated or is sufficiently porous to permit drug delivery through the wall material.

7. An intraluminal balloon that comprises a composition comprising

(a) at least one aliphatic polyketone;

(b) a coupling agent or a cross-linker; and

further comprising

(c) a thermoplastic polymer;

wherein the at least one aliphatic polyketone is derived from monomers consisting of carbon monoxide and alpha olefins.

8. The intraluminal balloon of claim 7, wherein the coupling agent comprises a zirconium or titanium coupling agent, or an epoxy modified polyolefin.

9. The intraluminal balloon of claim 7 further comprising a plasticizer, wherein the plasticizer comprises aromatic sulfonamides, aromatic phosphate esters, alkyl phosphate esters, alkyl esters, citrate esters, butyl benzosulfonamides, acetate, adipate, amides, azelates, epoxides, glutarates such as polyester glutarate, N,N-dimethyl caprylamide capramide, N,N-dimethyl oleamide, epoxidized glycol dioleate, analogs of any of the above, derivatives of any of the above or mixtures thereof.

10. The intraluminal balloon of claim 7, wherein the cross-linking agent comprises ethylene glycol dimethacrylate, triallyl isocyanurate, triallyl cyanurate, or triallyl 1,3,5-triazine-2,4,6(1 H,3 H,5 H)-trione.

11. The intraluminal balloon of claim 7 having a wall comprising a balloon wall material, wherein the balloon wall material is biaxially oriented.

12. The intraluminal balloon of claim 7, wherein the balloon is about 1.5 to 12 mm in diameter.

13. The intraluminal balloon of claim 7, wherein the balloon is capable of deploying a stent.

14. The intraluminal balloon of claim 7, wherein the balloon is semi-compliant.

16. An intraluminal balloon formed by a process comprising:

combining at least one aliphatic polyketone and a thermoplastic polymer with an additive comprising a coupling agent, a plasticizer, or a cross-linker; and

forming the combination of the at least one aliphatic polyketone and the substance into an intraluminal balloon;

wherein the at least one aliphatic polyketone is derived from monomers consisting of carbon monoxide and alpha olefins.

17. An intraluminal balloon formed by a process comprising:

combining at least one aliphatic polyketone with a thermoplastic polymer; and

forming the combination of the at least one aliphatic polyketone with a thermoplastic polymer into an intraluminal balloon;

wherein the at least one aliphatic polyketone is derived from monomers consisting of carbon monoxide and alpha olefins.