Apparatus and method for bone surface-based registration of physical space with tomographic images and for guiding an instrument relative to anatomical sites in the image

• US 6,106,464 A
• Filed: 02/22/1999
• Issued: 08/22/2000
• Est. Priority Date: 02/22/1999
• Status: Expired due to Term

• Current Assignee: Vanderbilt University
• Original Assignee: Vanderbilt University
• Inventors: Bass, Wayne A., Maurer, Calvin R. Jr., Galloway, Robert L. Jr., Maciunas, Robert J.
• Primary Examiner(s): Jaworski, Francis J.
• Application Number:
  US09/255,254
• Time in Patent Office: 547 Days
• Field of Search: 600/407, 600/424, 600/437, 600/439, 600/443, 600/459, 600/471, 606/130
• US Class Current: 600/439
• CPC Class Codes: A61B 2034/105 Modelling of the patient, e.g. for ligaments or bones
• CPC Class Codes: A61B 2034/2055 Optical tracking systems
• CPC Class Codes: A61B 2090/364 Correlation of different images or relation of image positions in respect to the body
• CPC Class Codes: A61B 2090/378 using ultrasound
• CPC Class Codes: A61B 34/20 Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
• CPC Class Codes: A61B 8/00 Diagnosis using ultrasonic, sonic or infrasonic waves imaging of objects using sonar G01S15/00
• CPC Class Codes: A61B 8/0816 using echo-encephalography
• CPC Class Codes: A61B 8/4245 involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient
• CPC Class Codes: A61B 8/4263 using sensors not mounted on the probe, e.g. mounted on an external reference frame
• CPC Class Codes: A61B 8/5238 for combining image data of patient, e.g. merging several images from different acquisition modes into one image for image registration algorithms G06T7/30
• CPC Class Codes: A61B 90/36 Image-producing devices or illumination devices not otherwise provided for

Abstract

An A-mode ultrasound transducer is tracked in three-dimensions by an optical position tracking system as the transducer is scanned over the skin to generate measurements of bone surface distance from the transducer. A processor correlates the ultrasound data with position and orientation data to generate a three-dimensional physical space model of the bone surface which is registered with an image space model of the bone surface generated from a tomographic image to produce an alignment of the two models. The ultrasound transducer is replaced by an instrument which is also optically tracked. The alignment is used to translate instrument position in physical space to a position in image space for generation on a monitor of a composite display of the instrument and the tomographic image. This composite display can be used to guide positioning and orienting the instrument in physical space with respect to sites of interest observed in the tomographic image on the display.

Claims

1. Apparatus for bone surface-based registration of physical space with a tomographic image, comprising:

an ultrasound transducer generating ultrasound signals representative of a distance from said transducer to said bone surface as said transducer is scanned over but spaced from said bone surface;

tracking means generating transducer position/orientation signals tracking transducer position and orientation as said transducer is scanned over said bone surface;

means synchronizing generation of said ultrasound signals with generation of said position signals;

physical model generating means generating from said ultrasound signals and transducer position/orientation signals a three-dimensional physical space model of said bone surface;

means generating a three-dimensional image space model of said bone surface from said tomographic image;

means generating an alignment of said physical space model and said image space model; and

output means generating an output utilizing said alignment.

2. The apparatus of claim 1 wherein said ultrasound transducer comprises an A-mode ultrasound transducer.

3. The apparatus of claim 2 wherein said output means comprises an instrument tracked by said tracking means to generate instrument position/orientation signals, a visual display, and means using said instrument position/orientation signals and said alignment for generating on said visual display a composite image comprising said tomographic image and a representation of said instrument in image space.

4. The apparatus of claim 3 wherein said tracking means comprises optical tracking means.

5. The apparatus of claim 3 wherein said instrument is selected from a group consisting of:

a surgical probe, a beam collimator emitting a beam, a cauterizer, a laser, a drill and a biopsy needle.

6. The apparatus of claim 5 wherein said ultrasound transducer comprises an A-mode ultrasound transducer.

7. The apparatus of claim 6 wherein said tracking means comprises optical tracking means.

8. The apparatus of claim 3 wherein said A-mode ultrasound transducer operates at about 5-20 MHz.

9. The apparatus of claim 8 wherein said A-mode ultrasound transducer operates at about 10 MHz.

10. The apparatus of claim 2 wherein said tracking means comprises optical tracking means.

11. The apparatus of claim 2 wherein said ultrasound transducer comprises an array of ultrasound transducers.

12. The apparatus of claim 2 wherein said A-mode ultrasound transducer has a predetermined focal length and including an offset which spaces said transducer from said bone surface by about said focal length.

13. The apparatus of claim 12 wherein said offset contains water.

14. The apparatus of claim 13 wherein said offset is a container containing water and having an end wall facing toward said bone surface having an aperture through which said ultrasound transducer is focused and being of size that water surface tension maintains said water in said container.

15. Apparatus for guiding positioning of an instrument relative to a bone surface displayed in a tomographic image, said apparatus comprising:

an instrument;

tracking means generating tracking signals tracking position and orientation of said instrument in physical space;

means providing an alignment of a model of said bone surface in physical space with a model of said bone surface in image space with the latter derived from said tomographic image;

a visual display; and

means using said tracking signals and said alignment to generate on said visual display a composite image comprising said tomographic image and a representation of said instrument in image space.

16. The apparatus of claim 15 wherein said tracking means is optical tracking means.

17. The apparatus of claim 16 wherein said instrument is selected from a group consisting of:

a surgical probe, a beam collimator emitting a beam, a cauterizer, a laser, a drill and a biopsy needle.

18. The apparatus of claim 16 wherein said means providing said alignment includes A-mode ultrasound means for generating said model of said bone surface in physical space.

19. A method of bone surface-based registration of physical space with a tomographic image comprising the steps of:

scanning an ultrasound transducer over but spaced from a bone surface to generate ultrasound signals representing a distance between the transducer and the bone surface;

tracking the transducer position and orientation as the transducer is scanned over said bone surface to generate transducer position/orientation signals;

generating a physical space model of said bone surface from said ultrasound signals and said transducer position/orientation signals;

generating an image space model from said tomographic image; and

registering the physical space model with the image space model to produce an alignment of said physical space model and said image space model.

20. The method of claim 19 further including tracking an instrument relative to said bone surface to generate instrument position/orientation signals;

using said alignment and said instrument position/orientation signals to generate a representation of said instrument in image space; and

generating on a display a composite image of said representation of said instrument in image space and said tomographic image, and using said display to position and orient said instrument in physical space.

21. The method of claim 20 wherein said instrument is selected from a group consisting of:

a surgical probe, a beam collimator emitting a beam, a cauterizer, a laser, a drill and a biopsy needle.

22. The method of claim 19 wherein said ultrasound transducer is an A-mode ultrasound transducer.

23. The method of claim 19 wherein said ultrasound transducer is an array of A-mode ultrasound transducers.