Endocardial device for producing reversible damage to heart tissue

• US 6,106,520 A
• Filed: 09/30/1998
• Issued: 08/22/2000
• Est. Priority Date: 09/30/1997
• Status: Expired due to Fees

• Current Assignee: Michael D. Laufer, Tony R. Brown
• Original Assignee: Hearten Medical, Inc.
• Inventors: Laufer, Michael D., Nguyen, Hien V., Stambaugh, Bruce D.
• Primary Examiner(s): Peffley, Michael
• Assistant Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US09/163,849
• Time in Patent Office: 692 Days
• Field of Search: 606/41, 606/42, 606/45, 606/49, 606/50, 606/32, 607/98-102, 604/22
• US Class Current: 606/32
• CPC Class Codes: A61B 18/1477 Needle-like probes
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61B 2018/00821 measured by a thermocouple
• CPC Class Codes: A61B 2018/1425 Needle

Abstract

A minimally invasive medical or surgical device creates holes in heart tissue utilizing a needle connected to an energy source, such a radio frequency generator, a resistive heating source, or a microwave energy source. The needle is inserted into heart tissue from an interior of the heart and activated to heat the surrounding tissue in order to produce reversible tissue damage. The device consists of an energy source and regulator, electric contacts to the energy source, a catheter, and a needle at the distal end of the catheter for delivering energy to the heart tissue. The catheter is fed through the vasculature into the interior of the heart. A temperature sensor may be positioned on the needle for sensing a temperature of the heart tissue in which the needle has been inserted. Preferably, a regulator is connected to the energy source and to the temperature sensor for controlling the temperature of the heart tissue in which the needle has been inserted to about 40° C. to about 60° C. as sensed by the temperature sensor.

Claims

1. A method of treating ischemia and angina by causing reversible damage to myocardial tissue, the method comprising:

inserting a needle in a minimally invasive manner through the vasculature to an interior of the heart;

penetrating the myocardial tissue with the needle from the interior of the heart;

heating the myocardial tissue by applying energy to the needle to create a zone of reversible tissue damage around the needle; and

withdrawing the needle, reinserting the needle, and heating to form a plurality of spaced apart zones of reversible tissue damage.

2. The method of treating ischemia and angina of claim 1, wherein the myocardial tissue is heated to between about 40°

C. and about 60°

C. with the needle to create the zone of reversible tissue damage around the needle.

3. The method of treating ischemia and angina of claim 2, wherein the tissue is heated for between about 5 seconds and about 120 seconds.

4. The method of treating ischemia and angina of claim 1, wherein the needle is inserted part way through a heart wall.

5. The method of treating ischemia and angina of claim 1, wherein the myocardial tissue is heated by applying radio frequency energy to the needle.

6. The method of treating ischemia and angina of claim 1, wherein the myocardial tissue is heated by resistance heating of the needle.

7. The method of treating ischemia and angina of claim 1, wherein myocardial tissue is heated by applying microwave energy to the needle.

8. The method of treating ischemia and angina of claim 1, wherein the myocardial tissue is heated to a temperature of between about 44°

C. and about 50°

C.