Bifurcated biological pulmonary valved conduit
First Claim
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1. A vascular prosthetic suitable for replacing a patient'"'"'s damaged or missing pulmonary valve, said prosthetic comprising:
- an inflow conduit comprising a manifold formed from the sealed attachment of a plurality of donor valved blood vessels, each of said blood vessels housing a biological valve integral therewith, said blood vessels configured to permit the flow of blood therethrough by the valve opening at a relatively low pressure and configured to prevent the backflow of blood therethrough by the valve closing so as to withstand relatively high pressures, said manifold formed upstream of each of the biological valves so as not to interfere with the effective operation of the biological valves, said inflow conduit having a resulting flow capacity following sealed attachment that is larger than the original flow capacity of each of the donor blood vessels, andan outflow conduit positioned downstream of each of the biological valves.
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Abstract
The present invention comprises a pulmonary valved conduit that permits inflow diameters greater than about 22 mm while still maintaining the advantages of a naturally-formed biological valved conduit. Specifically, the present invention comprises a valved vascular prosthetic having an inflow conduit comprising a manifold formed from the sealed attachment of at least two venous valvular conduits.
313 Citations
29 Claims
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1. A vascular prosthetic suitable for replacing a patient'"'"'s damaged or missing pulmonary valve, said prosthetic comprising:
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an inflow conduit comprising a manifold formed from the sealed attachment of a plurality of donor valved blood vessels, each of said blood vessels housing a biological valve integral therewith, said blood vessels configured to permit the flow of blood therethrough by the valve opening at a relatively low pressure and configured to prevent the backflow of blood therethrough by the valve closing so as to withstand relatively high pressures, said manifold formed upstream of each of the biological valves so as not to interfere with the effective operation of the biological valves, said inflow conduit having a resulting flow capacity following sealed attachment that is larger than the original flow capacity of each of the donor blood vessels, and an outflow conduit positioned downstream of each of the biological valves. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A method of forming a vascular prosthetic that is suitable for implantation within a human to restore pulmonary valvular function, said method comprising the steps of:
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extracting first and second vein segments from a biological source, each vein segment having at least one naturally formed venous valve formed therein, each vein segment further having an unvalved portion which is upstream from the at least one venous valve; and laterally joining the vein segments along the unvalved portions thereof to form an inflow conduit having a cross sectional area that is substantially larger than the cross sectional area of either the first or the second vein segment. - View Dependent Claims (25, 26, 27, 28)
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29. A method of treating a damaged or missing pulmonary valve in a patient, said method comprising the steps of using two or more donor, venous, valvular vessels spliced together to form a single vascular prosthetic having an inflow portion that has a cross-sectional area larger than the cross-sectional area of any of said donor venous valvular blood vessels.
Specification