Method and apparatus for determining cardiac performance in a patient

• US 6,112,115 A
• Filed: 03/09/1999
• Issued: 08/29/2000
• Est. Priority Date: 03/09/1999
• Status: Expired due to Term

• Current Assignee: Cardiovol, LLC
• Original Assignee: Conductance Technologies, Inc.
• Inventors: Feldman, Marc D., Wu, Clarence, Mahler, Christine
• Primary Examiner(s): Getzow, Scott M.
• Application Number:
  US09/265,092
• Time in Patent Office: 539 Days
• Field of Search: 600/513, 600/526, 600/483, 600/484, 600/485
• US Class Current: 600/513
• CPC Class Codes: A61B 5/0215 by means inserted into the body catheters A61M25/00
• CPC Class Codes: A61B 5/0295 using plethysmography, i.e. measuring the variations in the volume of a body part as modified by the circulation of blood therethrough, e.g. impedance plethysmography
• CPC Class Codes: A61B 5/0535 Impedance plethysmography for measuring blood flow A61B5/0295
• CPC Class Codes: A61B 5/0538 invasively, e.g. using a catheter
• CPC Class Codes: A61B 5/287 Holders for multiple electrodes, e.g. electrode catheters for electrophysiological study [EPS]

Abstract

The present invention pertains to an apparatus for determining cardiac performance in a patient. The apparatus comprises a conductance catheter which can be excited with multiple frequencies for measuring instantaneous volume of a heart chamber. The apparatus comprises a mechanism for measuring instantaneous pressure of the heart chamber. The apparatus comprises a mechanism for processing the instantaneous volume and the pressure of the heart chamber to identify mechanical strength of the chamber and for automatically producing a plurality of desired waveforms at desired frequencies for the conductance catheter. The processing mechanism is connected to the pressure measuring mechanism and the volume measuring mechanism. The present invention pertains to a method for determining cardiac performance in a patient. The method comprises the steps of applying automatically multifrequencies to a conductance catheter. Then there is the step of measuring the instantaneous volume of a heart chamber of the patient. Next there is the step of measuring the instantaneous pressure of the heart chamber. Then there is the step of identifying mechanical strength of the chamber from the instantaneous volume and pressure.

Claims

1. An apparatus for determining cardiac performance in a patient comprising:

a multifrequency conductance catheter for measuring instantaneous volume of a heart chamber;

a mechanism for measuring instantaneous pressure of the heart chamber; and

a mechanism for signal processing the instantaneous volume and the pressure of the heart chamber to identify mechanical strength of the chamber and for automatically producing a plurality of desired waveforms at desired frequencies for the conductance catheter, said processing mechanism connected to the pressure measuring mechanism and the volume measuring mechanism.

2. An apparatus as described in claim 1 wherein the signal processing mechanism combines the instantaneous volume and pressure with a first derivative of pressure to identify the mechanical strength of the chamber.

3. An apparatus as described in claim 2 wherein the conductance catheter includes a plurality of electrodes to measure at least one segmental volume of the heart chamber.

4. An apparatus as described in claim 3 wherein the conductance catheter includes at least one pressure sensor to measure ventricular pressure in the chamber.

5. An apparatus as described in claim 4 wherein the electrodes measure the EKG.

6. An apparatus as described in claim 5 wherein the signal processing mechanism includes a computer with a signal synthesizer and a data acquisition mechanism connected to the catheter.

7. An apparatus as described in claim 6 wherein the signal processing mechanism includes a mechanism for converting conductance into a volume, said converting mechanism connected to the catheter and the computer.

8. An apparatus as described in claim 7 wherein the signal processing mechanism includes a mechanism for producing a drive signal to drive the conductance catheter, said producing mechanism connected to the catheter and the computer.

9. An apparatus as described in claim 8 wherein the converting mechanism includes signal processing circuitry for converting measured conductance to a volume, said signal processing circuitry connected to the catheter and the computer.

10. An apparatus as described in claim 9 wherein the converting mechanism includes a signal conditioning/filter mechanism for reducing noise level of measured conductance, said signal conditioning/filter mechanism connected to the signal processing circuitry and the computer.

11. An apparatus as described in claim 10 wherein the converting mechanism includes a pressure amplifier which amplifies the signal from the solid state pressure sensor, said pressure amplifier connected to the catheter and the signal conditioning/filter mechanism.

12. An apparatus as described in claim 11 wherein the drive mechanism includes an internal oscillator which generates an amplitude excitation voltage at least at two different frequencies, said internal oscillator connected to the computer and the catheter.

13. An apparatus as described in claim 12 wherein the drive mechanism includes a voltage-to-current converter which converts excitation voltage to a current, said voltage-to-current converter connected to the internal oscillator and the catheter.

14. An apparatus as described in claim 13 wherein the drive mechanism includes an external input signal synthesizer mechanism for controlling the signal synthesizer of the computer to produce desired waveforms at desired frequencies, said external input signal synthesizer mechanism connected to the computer.

15. A method for determining cardiac performance in a patient comprising the steps of:

applying automatically multifrequencies to a conductance catheter;

measuring the instantaneous volume of a heart chamber of the patient;

measuring the instantaneous pressure of the heart chamber; and

identifying mechanical strength of the chamber from the instantaneous volume and pressure.

16. A method as described in claim 15 wherein the measuring the first volume step includes the step of measuring the volume with a conductance catheter.