Endovascular stent with support wire

• US 6,113,628 A
• Filed: 11/20/1997
• Issued: 09/05/2000
• Est. Priority Date: 06/08/1995
• Status: Expired due to Fees

• Current Assignee: AVE Galway Limited
• Original Assignee: AVE Galway Limited
• Inventors: Borghi, Enzo
• Primary Examiner(s): Prebilic, Paul B.
• Application Number:
  US08/952,640
• Time in Patent Office: 1,020 Days
• Field of Search: 623/1, 623/12, 623/1.16, 623/1.17, 623/901, 606/195, 606/198, 600/36
• US Class Current: 623/1.16
• CPC Class Codes: A61F 2/856 Single tubular stent with a side portal passage
• CPC Class Codes: A61F 2/86 Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/88 the wire-like elements formed as helical or spiral coils forming a net-like or mesh-like structure A61F2/90
• CPC Class Codes: A61F 2/954 for placing stents or stent-grafts in a bifurcation
• CPC Class Codes: A61F 2/958 Inflatable balloons for placing stents or stent-grafts
• CPC Class Codes: A61F 2002/065 Y-shaped blood vessels
• CPC Class Codes: A61F 2002/067 modular
• CPC Class Codes: A61F 2002/828 Means for connecting a plurality of stents allowing flexibility of the whole structure
• CPC Class Codes: A61F 2250/0015 differing in density or specific weight
• CPC Class Codes: A61F 2250/0067 Means for introducing or releasing pharmaceutical products into the body
• CPC Class Codes: A61F 2310/00023 Titanium or titanium-based alloys, e.g. Ti-Ni alloys
• CPC Class Codes: A61F 2310/00059 Chromium or Cr-based alloys
• CPC Class Codes: A61F 2310/00071 Nickel or Ni-based alloys
• CPC Class Codes: A61F 2310/00155 Gold or Au-based alloys
• CPC Class Codes: A61F 2310/00161 Carbon; Graphite

Abstract

An endoluminal stent is formed in a modular construction to include an elongate spine and a plurality of generally tube-defining modules attached to the spine in a longitudinally sequenced array. Each module defines, in cooperation with the spine, a closed ring-like structure, with the modules being aligned in an array to define a generally tubular structure. Each of the modules is radially expandable from a reduced diameter, low profile configuration, in which it is readily navigated through the body passages, to an expanded diameter engageable with the inner luminal surface of the body lumen. The stent, being of modular construction, can be built to individual specifications for specific procedure in a specific patient. Modules are formed from a wire shaped in a flat serpentine configuration that is then wrapped in a cylindrical configuration with its free ends connected to the spine. The modules are expandable, as by a balloon, from a low profile to an expanded configuration. During expansion, the modules can wipe against the inner surface of the lumen to smooth sharp points or edges. The spine of the stent defines a substantially greater mass than that of the individual modules such that the spine can be readily observed under X-ray or fluoroscopy. The modular construction enables a wide range of variation in the characteristics of the stent, including longitudinal flexibility and radial expansion characteristics, among others.

Claims

1. An endoprosthesis for a body lumen comprising:

an elongate support wire; and

a plurality of modules supported on the support wire at sequential locations along the support wire, each of the plurality of modules being connected to the support wire by a connector secured to the module and attached to the support wire,

wherein each module of the plurality of modules defines a closed circumferential loop, the modules being arranged on the support wire to define a generally tubular configuration, and

wherein the modules are constructed to be expandable from a radially contracted configuration in which the endoprosthesis can be positioned in the body lumen to a radially expanded configuration, and

wherein each module is formed from a serpentine wire having a plurality of elongate segments alternated with shorter connective bends, and

wherein the serpentine wire has free terminal ends attached to the connector to secure the module in its closed circumferential loop configuration, and

wherein the connector includes an aperture receptive to the support wire and the free terminal ends of the serpentine wire of the associated module.

2. An endoprosthesis as defined in claim 1 wherein the connector comprises a ring adapted to surround each of the free terminal ends of its associated module and the support wire.

3. An endoprosthesis as defined in claim 2 wherein the module, connector and support wire are connected by one of or a combination of spot welding and crimping.

4. An endoprosthesis as defined in claim 1

wherein a radially outward facing surface of the connector is curved to facilitate its conformance to the curved shape of a wall of the body lumen.

7. An endoprosthesis as defined in claim 1 wherein the end modules of the endoprosthesis are attached to the support wire with their free terminal ends oriented toward each other.

8. An endoprosthesis as defined in claim 2 wherein the internal contour of the ring is adapted to surround closely and substantially conform to the external contour of the free terminal ends and support wire.

9. An endoprosthesis as defined in claim 1, wherein an angle is formed between adjacent elongate segments of said plurality of elongate segments of said at least one module.

10. An endoprosthesis as defined in claim 9, wherein said angle is between 45 degrees and 85 degrees when said at least one module is in said radially expanded configuration.

11. An endoprosthesis as defined in claim 1, further comprising a spacer mounted on said support wire between at least one pair of modules.

12. An endoprosthesis as defined in claim 11, wherein said spacer has a greater mass than said modules.

13. An endoprosthesis as defined in claim 1, wherein a region of connection between each of said modules and said support wire has a mass with greater radiopacity than said expandable modules.

14. An endoprosthesis as defined in claim 11, wherein an outer surface of said spacer is curved to facilitate its conformance to the curved shape of a wall of the body lumen.

15. An endoprosthesis as defined in claim 1, wherein said bends are arranged in a substantially uniform circumferential distribution along the locus of the closed loop.

16. An endoprosthesis as defined in claim 1, further comprising a second longitudinal wire connected to said modules and extending general parallel to said support wire.

17. An endoprosthesis as defined in claim 1, wherein said modules and said support wire have different malleability.

18. An endoprosthesis as defined in claim 1, wherein said module is formed from a material belonging to the group comprising annealed steel, titanium alloys, nickel gold alloys, nickel chromium alloys, and titanium chromium alloys.

19. An endoprosthesis as defined in claim 1, wherein the endoprosthesis is coated with a protective material.

20. An endoprosthesis as defined in claim 19, wherein said protective material comprises carbon.

21. An endoprosthesis as defined in claim 1, wherein the endoprosthesis is coated with a drug.

22. An endoprosthesis as defined in claim 21, wherein said drug comprises an anticoagulent.

23. An endoprosthesis as defined in claim 1, wherein the endoprosthesis is dimensioned to be receivable in a human coronary artery when in said radially contracted configuration and engages inner walls of said artery when in said radially expanded configuration.

24. An endoprosthesis as defined in claim 1, wherein said connector further comprises a ring having an inside face and an opposite outside face, said outside face being rounded and adapted to conform to a nominally cylindrical wall of the body lumen.

25. An endoprosthesis as defined in claim 24, wherein said inside face of said ring is substantially flat.

26. An endoprosthesis as defined in claim 24, further comprising a spacer disposed on said support wire adjacent said connector, an external surface of said spacer defining a rounded profile substantially corresponding to said rounded outside face of said connector.

5. An endoprosthesis for a body lumen comprising:

an elongate support wire;

a plurality of modules supported on the support wire at sequential locations along the support wire, each of the modules being connected to the support wire by a connector secured to the module and attached to the support wire;

each module defining a closed circumferential loop the modules being arranged on the support wire to define a generally tubular configuration;

the modules being constructed to be expandable from a radially contracted configuration in which it can be positioned in the body lumen to a radially expanded configuration;

a spacer mounted on the support wire between at least one pair of modules;

wherein an outer surface of the spacer is curved to facilitate its conformance to the curved shape of a wall of the body lumen.

6. An endoprosthesis as defined in claim 5 wherein the outwardly exposed surface of the spacer is contoured to correspond substantially to the contour presented by the outwardly facing surface of its adjacent connectors thereby to present a substantially smooth and continuous surface adapted to bear against and conform with the contour of the body lumen.