Implantable stimulator

• US 6,115,633 A
• Filed: 10/27/1997
• Issued: 09/05/2000
• Est. Priority Date: 10/28/1996
• Status: Expired due to Term

• Current Assignee: Biotronik Mess-Und Therapiegeraete GmbH & Company Ingenieurbuero Berlin (Biotronik SE & Company KG)
• Original Assignee: Biotronik Mess-Und Therapiegeraete GmbH & Company Ingenieurbuero Berlin (Biotronik SE & Company KG)
• Inventors: Lang, Volker, Bolz, Armin
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US08/958,199
• Time in Patent Office: 1,044 Days
• Field of Search: 607/9, 607/17, 607/24, 600/547
• US Class Current: 607/17
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/36514 controlled by a physiological quantity other than heart potential, e.g. blood pressure controlled by two or more physical parameters A61N1/36585
• CPC Class Codes: A61N 1/36571 controlled by blood flow rate, e.g. blood velocity or cardiac output

Abstract

An implantable stimulator for treating arrhythmic function disturbances of a heart, comprising; a stimulation electrode for transmitting stimulation pulses to the heart, a pulse generator that is connected to the stimulation electrode for generating the stimulation pulses, a control unit connected to the pulse generator for controlling the pulse emissions, a hemodynamic sensor for controlling the pulse emission as a function of the cardiac pumping performance, the hemodynamic sensor including; two measuring electrodes located in or in electrical contact with a blood vessel, for measuring the blood impedance dependent on the blood throughput, a signal generator that generates an AC voltage for generating a test signal for impedance measurement, an electrical measuring device connected to the twvo measuring electrodes for determining the blood throughput as a function of the measured electrical signal; and a blood throughput signal-analysis unit for recognizing an arrhythmic cardiac finction disturbance using the measured throughput quantity.

Claims

1. An implantable stimulator for treating arrhythmic function disturbances of a heart, comprising:

a stimulation electrode for transmitting stimulation pulses to the heart, the electrode being adapted to be disposed in one of the heart and the vicinity thereof;

pulse generator that is connected on an output side to the stimulation electrode for generating the stimulation pulses;

a control unit that is connected on an output side to the pulse generator for controlling the pulse emission by the pulse generator;

a hemodynamic sensor for controlling the pulse emission as a function of the cardiac pumping performnance, the hemodynamic sensor including;

two measuring electrodes spaced apart and adapted to be located outside of the heart and one of in a blood vessel and in electrical contact with a blood vessel, for measuring the blood impedance dependent on the blood vessel throughput;

a signal generator that generates an AC voltage in a range below 10 kHz for generating a test signal for impedance measurement, the generator being coupled to the two measuring electrodes for generating an electrical field between the two measuring electrodes;

an electrical measuring device having an input side connected to the two measuring electrodes for determining the blood vessel throughput as a function of a measured electrical signal from the two measuring electrodes; and

a blood vessel throughput signal-analysis unit having an input side connected to the electrical measuring device and having an output side connected to the control unit for recognizing an arrhythmic cardiac function disturbance using the measured throughput quantity.

2. The stimulator according to claim 1, wherein the control unit is connected on an input side to the stimulation electrode for detecting spontaneous cardiac signals and for controlling the pulse emission as a function of both the measured blood throughput and the spontaneous cardiac signals, and includes a first cardiac signal analysis unit having an input side connected to the output of the electrode for recognizing a cardiac function disturbance using the measured spontaneous cardiac signals.

3. The stimulator according to claim 2, wherein the control unit includes a logic unit for evaluating both the measured blood throughput and the cardiac signals, the logic unit being connected on an input side to the cardiac signal analysis unit for assessing the cardiac signals, and to the blood throughput signal-analysis unit for assessing the cardiac pumping performance.

4. The stimulator according to claim 1, further comprising a controllable switching element for switching the hemodynamic sensor on and off.

5. The stimulator according to claim 4, wherein a control input of the controllable switching element is connected to an output of the cardiac signal analysis unit for switching on the sensor when a disturbance in the cardiac function is detected by the cardiac signal analysis unit and for switching off the sensor when a cardiac function that has been corrected is detected by the cardiac signal analysis unit.

6. The stimulator according to claim 4, wherein the control input of the controllable switching element is connected to one of a timer for switching the hemodynamic sensor on and off with time control, and a telemetry receiver for remote-controlled switching on and off by an extracorporeal control device.

7. The stimulator according to claim 1, wherein the two measuring electrodes are adapted to be disposed in one of (1) one behind the other in the flow direction for longitudinal impedance measurement and (2) adjacently to one another transversely to the flow direction, for transversal impedance measurement.

8. The stimulator according to claim 1, wherein the hemodynamic sensor is adapted to be disposed in one of the vena cava and the pulmonary artery.

9. The stimulator according to claim 1, wherein a measuring voltage in a range of 0.3 V to 3 V, and a measuring current in a range of 10 μ

A to 100 μ

A are set by the signal generator and the series resistor.

10. The stimulator according to claim 1, further including means are connected to an input of the blood throughput signal analysis unit, for compensating for at least one of the influence of temperature- and medication-stipulated changes in the blood throughput.

11. The stimulator according to claim 1, wherein the control unit has an input side connected to a further electrode for detecting spontaneous cardiac signals and the control unit further includes a cardiac signal analysis unit having an input side connected to the output of the electrode for recognizing a cardiac function disturbance using the measured spontaneous cardiac signals and for controlling the pulse emission as a function of both the measured blood throughput and the spontaneous cardiac signals.