Treatment of gastrointestinal ulcers or gastritis caused by microbial infection
First Claim
1. A method of treatment of infectious stomach disease caused by infection of gastrointestinal tissue with Helicobacter pylori in a mammal, comprising administering to said mammal an antimicrobial amount of an antimicrobial medicament selected from the group consisting of taurolidine, taurultam and a combination thereof, so as to contact said infected gastrointestinal tissue with said antimicrobial medicament and treat said disease in said mammal.
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Accused Products
Abstract
A method and composition for the treatment of infectious gastrointestinal ulcer disease or infectious gastritis disease of microbially infected gastrointestinal tissue in a mammal involves administration of an antimicrobial amount of an antimicrobial medicament which is cell wall constituent-inactivating by chemical reaction with cell wall constituents, endotoxin non-releasing, exotoxin-inactivating or a combination thereof.
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Citations
13 Claims
- 1. A method of treatment of infectious stomach disease caused by infection of gastrointestinal tissue with Helicobacter pylori in a mammal, comprising administering to said mammal an antimicrobial amount of an antimicrobial medicament selected from the group consisting of taurolidine, taurultam and a combination thereof, so as to contact said infected gastrointestinal tissue with said antimicrobial medicament and treat said disease in said mammal.
- 9. A pharmaceutical composition for treatment of an infectious stomach disease caused by infection of gastrointestinal tissue with Helicobacter pylori in a mammal, comprising an antimicrobial amount of an antimicrobial medicament selected from the group consisting of taurolidine, taurultam and a combination thereof, said pharmaceutical composition further comprising a pharmaceutically acceptable gastric acid-neutralizing stomach antacid.
- 10. A pharmaceutical composition for treatment of an infectious stomach disease caused by infection of gastrointestinal tissue with Helicobacter pylori in a mammal, comprising an antimicrobial amount of an antimicrobial medicament selected from the group consisting of Taurolidine, Taurultam and a combination thereof, said pharmaceutical composition further comprising a pharmaceutically acceptable proton pump inhibitor.
Specification