System and method for gated radiotherapy based on physiological inputs

• US 6,118,847 A
• Filed: 08/06/1998
• Issued: 09/12/2000
• Est. Priority Date: 01/15/1998
• Status: Expired due to Term

• Current Assignee: Siemens Medical Solutions USA Incorporated (Siemens AG)
• Original Assignee: Siemens Medical Systems, Inc. (Siemens AG)
• Inventors: Merola, Pat, Calderon, Edward Lewis, Hernandez-Guerra, Francisco M., Forknall, Simon John, Pond, David L., Alrifai, Hussein
• Primary Examiner(s): Porta, David P.
• Assistant Examiner(s): Dunn, Drew A.
• Application Number:
  US09/130,303
• Time in Patent Office: 768 Days
• Field of Search: 378/65, 378/105, 378/108, 378/195, 378/119, 378/95, 250/492.1, 250/492.3, 250/505.1
• US Class Current: 378/65
• CPC Class Codes: A61B 2017/00699 correcting for movement caused by respiration, e.g. by triggering
• CPC Class Codes: A61B 6/541 involving acquisition triggered by a physiological signal
• CPC Class Codes: A61N 5/1037 taking into account the movement of the target, e.g. 4D-image based planning
• CPC Class Codes: A61N 5/1042 with spatial modulation of the radiation beam within the treatment head
• CPC Class Codes: A61N 5/1048 Monitoring, verifying, controlling systems and methods
• CPC Class Codes: A61N 5/1064 for adjusting radiation treatment in response to monitoring
• CPC Class Codes: H05H 7/12 Arrangements for varying final energy of beam

Abstract

A radiation therapy device (2) configured to receive a signal indicative of one or more of a patient'"'"'s physiological parameters. The signal controls a gating, whereby a phase of an RF pulse (1002) and an injector pulse (1006) are varied so as to inhibit X-ray production without affecting injector or RF amplitudes.

Claims

1. A controller for a radiation therapy apparatus comprising:

an interface configured to receive one or more inputs indicative of a state of one or more of a patient'"'"'s physiological parameters; and

a gating controller, said gating controller configured to vary a phase between an RF pulse and an injector pulse responsive to said one or more inputs.

2. A controller according to claim 1, wherein said one or more inputs includes one or more inputs responsive to a heart monitor.

3. A controller according to claim 1, wherein said one or more inputs includes one or more inputs responsive to a muscle monitor.

4. A controller according to claim 1, wherein said one or more inputs includes one or more inputs responsive to a respiratory monitor.

5. A controller according to claim 1, wherein said one or more inputs includes one or more inputs responsive to a brain wave monitor.

6. A method for delivering radiation therapy, comprising:

receiving one or more signals indicating that a state of one or more of a patient'"'"'s physiological parameters have matched one or more predetermined criteria; and

varying a phase between an RF pulse and an injector pulse responsive to said receiving.

7. A method according to claim 6, wherein said state includes a state of a heart parameter.

8. A method according to claim 6, wherein said state includes a state of a muscle parameter.

9. A method according to claim 6, wherein said state includes a state of a respiratory parameter.

10. A method according to claim 6, wherein said state includes a state of a brain parameter.

11. A radiation therapy apparatus, comprising:

means for delivering a radiation dose to a patient; and

a controller for receiving an input signal indicative of one or more of said patient'"'"'s physiological parameters, said controller configured to dynamically vary application of said dose responsive to said input, said controller configured to vary a phase between an RF pulse and an injector pulse responsive to said one or more inputs.

12. A radiation therapy apparatus according to claim 11, said controller configured to execute an interlock responsive to detection of a dose during a period when said RF pulse and said injector pulse are out of phase.

13. A radiation therapy apparatus according to claim 11, said input signal indicative of a respiratory parameter.

14. A radiation therapy apparatus according to claim 11, said input signal indicative of a heart parameter.

15. A radiation therapy system, comprising:

an apparatus for delivering a predetermined radiation dose to a patient;

an interface configured to receive one or more input signals indicative of one or more of said patient'"'"'s physiological parameters; and

a controller configured to vary a phase between an RF pulse and an injector pulse, whereby substantially no radiation is delivered to said patient when said RF pulse and said injector pulse are out of phase, and wherein said phase is varied responsive to said one or more signals indicative of one or more of said patient'"'"'s physiological parameters.

16. A radiation therapy system according to claim 15, wherein said controller is configured to vary said phase by inserting a predetermined delay between said RF pulse and said injector pulse.

17. A radiation therapy system according to claim 15, said interface including an opto-isolator for receiving said one or more inputs.

18. A radiation therapy system according to claim 15, said controller configured to generate an interlock if more than a predetermined level of radiation is detected during a period when said RF pulse and said injector pulse are out of phase.

19. A radiation therapy system according to claim 15, said one or more inputs indicative of a respiratory parameter.