Method and system for synthesizing the 12-lead electrocardiogram

• US 6,119,035 A
• Filed: 03/26/1998
• Issued: 09/12/2000
• Est. Priority Date: 03/26/1998
• Status: Expired due to Term

• Current Assignee: Koninklijke Philips N.V.
• Original Assignee: Hewlett-Packard Company (HP Inc.)
• Inventors: Wang, Jyh-Yun J.
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Application Number:
  US09/048,632
• Time in Patent Office: 901 Days
• Field of Search: 600/509, 600/512, 600/521
• US Class Current: 600/509
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/327 Generation of artificial ECG signals based on measured signals, e.g. to compensate for missing leads

Abstract

A method and system are provided for quickly and efficiently producing multiple syntheses of 12-lead electrocardiographs utilizing fewer than the 12 leads provided by a full electrode set. The method and system achieve their objects as follows. One or more 12-lead electrocardiograph leads are synthesized from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads. In response to user-defined parameters, one or more 12-lead electrocardiograph leads are synthesized from a second subset, different than the first subset, of a patient'"'"'s physically present 12-lead electrocardiograph leads. Also set forth are a method and system are provided for synthesizing a 12-lead electrocardiograph utilizing fewer than the 12 leads provided by a full electrode set. Therein, a subset of the full electrode set is attached to a patient. A subset of 12-lead electrocardiograph leads formed by the attached subset is identified. In response to the identified subset of 12-lead electrocardiograph leads, a synthesis matrix is recalled. In response to the recalled synthesis matrix, an accuracy factor associated with the recalled synthesis matrix is recalled. And, one or more 12-lead electrocardiograph leads are synthesized by applying the recalled synthesis matrix and the recalled accuracy factor to the identified subset of 12-lead electrocardiograph leads formed by the attached subset. Also set forth are a method and system for assessing the accuracy of synthesis electrocardiograph leads. Therein, one or more additional electrodes are attached to the patient. One or more 12-lead electrocardiograph leads are generated from the attached one or more additional electrodes. And, the generated one or more 12-lead electrocardiograph leads are compared with correspondent synthesized one or more 12-lead electrocardiograph leads.

Claims

1. A method for synthesizing a 12-lead electrocardiograph utilizing fewer than the 12 leads provided by a full electrode set, said method comprising the steps of:

attaching a subset of the full electrode set to a patient;

identifying a subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set;

in response to said identified subset of 12-lead electrocardiograph leads, recalling a synthesis matrix;

in response to said recalled synthesis matrix, recalling an accuracy factor associated with said recalled synthesis matrix; and

synthesizing one or more 12-lead electrocardiograph leads by applying said recalled synthesis matrix and said recalled accuracy factor associated with said recalled synthesis matrix to said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

2. The method of claim 1, wherein said step of recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset further comprises the steps of:

designating a patient profile; and

recalling a patient-independent synthesis matrix associated with both said designated patient profile and said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

3. The method of claim 1, wherein said step of recalling said accuracy factor associated with said recalled synthesis matrix further comprises the step of recalling an accuracy factor indicative of the accuracy of each individual synthesized lead to be generated by the utilization of said recalled synthesis matrix.

4. The method of claim 3, wherein said step of recalling said accuracy factor indicative of the accuracy of each individual synthesized lead to be generated by the utilization of said recalled synthesis matrix further comprises the step of recalling a standard deviation of said each representative individual synthesized lead from correspondent actual leads in a database utilized to generate said synthesis.

5. The method of claim 3, wherein said step of recalling said accuracy factor indicative of the accuracy of each individual synthesized lead to be generated by the utilization of said recalled synthesis matrix further comprises the step of recalling an average accuracy factor drawn upon a standard deviation of said each representative individual synthesized lead from correspondent actual leads in a database utilized to generate said synthesis matrix.

6. The method of claim 1, wherein said step of recalling a synthesis matrix further comprises the step of recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

7. The method of claim 6, wherein said step of recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set further comprises the steps of recalling a patient-independent synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

8. The method of claim 6, wherein said step of recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set further comprises the steps of recalling a patient-dependent synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

9. A method for quickly and efficiently producing multiple syntheses of 12-lead electrocardiographs utilizing fewer than the 12 leads provided by a full electrode set, said method comprising the steps of:

synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads; and

in response to user-defined parameters, synthesizing one or more 12-lead electrocardiograph leads from a second subset, different than said first subset, of a patient'"'"'s physically present 12-lead electrocardiograph leads.

10. The method of claim 9, wherein said step of synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises the steps of:

attaching a first subset of the full electrode set to said patient;

identifying a first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set; and

synthesizing one or more 12-lead electrocardiograph leads from said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

11. The method of claim 10, wherein said step of synthesizing from said identified first subset further comprises the steps of:

in response to said identified first subset of 12-lead electrocardiograph leads, recalling a first synthesis matrix; and

synthesizing one or more 12-lead electrocardiograph leads by applying said recalled first synthesis matrix to said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

12. The method of claim 11, wherein said step of recalling a first synthesis matrix further comprises the step of recalling a first patient-independent synthesis matrix associated with said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

13. The method of claim 11, wherein said step of recalling a first synthesis matrix further comprises the step of recalling a first patient-dependent synthesis matrix associated with said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

14. The method of claim 10, wherein said step of synthesizing from said identified first subset further comprises the steps of:

designating a patient profile;

recalling a first patient-independent synthesis matrix associated with both said designated patient profile and said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set; and

synthesizing one or more 12-lead electrocardiograph leads by applying said recalled first patient-independent synthesis matrix associated with both said designated patient profile and said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set to said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

15. The method of claim 9, wherein said step of synthesizing one or more 12-lead electrocardiograph leads from a second subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises the steps of:

attaching a second subset, different from said attached first subset, of the full electrode set to said patient;

identifying a second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set; and

synthesizing one or more 12-lead electrocardiograph leads from said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

16. The method of claim 15, wherein said step of synthesizing from said identified second subset further comprises the steps of:

in response to said identified second subset of 12-lead electrocardiograph leads, recalling a second synthesis matrix; and

synthesizing one or more 12-lead electrocardiograph leads by applying said recalled second synthesis matrix to said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

17. The method of claim 16, wherein said step of recalling a second synthesis matrix further comprises the step of recalling a second patient-independent synthesis matrix associated with said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

18. The method of claim 16, wherein said step of recalling a second synthesis matrix further comprises the step of recalling a second patient-dependent synthesis matrix associated with said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

19. The method of claim 15, wherein said step of synthesizing from said identified second subset further comprises the steps of:

designating a patient profile;

recalling a second patient-independent synthesis matrix associated with both said designated patient profile and said identified second subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set; and

synthesizing one or more 12-lead electrocardiograph leads by applying said recalled second patient-independent synthesis matrix associated with both said designated patient profile and said identified second subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set to said identified second subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

20. The method of claim 9, wherein said step of synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises the step of synthesizing one or more 12-lead electrocardiograph leads by applying a recalled synthesis matrix and a recalled accuracy factor associated with said recalled synthesis matrix to an identified subset of 12-lead electrocardiograph leads formed by an attached subset of the full electrode set.

21. The method of claim 9, wherein said step of synthesizing one or more 12-lead electrocardiograph leads from a second subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises the step of synthesizing one or more 12-lead electrocardiograph leads by applying a recalled synthesis matrix and a recalled accuracy factor associated with said recalled synthesis matrix to an identified subset of 12-lead electrocardiograph leads formed by an attached subset of the full electrode set.

22. A method for assessing the accuracy of synthesized electrocardiograph leads, said method comprising:

synthesizing one or more electrocardiograph leads;

attaching one or more additional electrodes to the patient;

generating one or more electrocardiograph leads from said attached one or more additional electrodes; and

comparing said generated one or more electrocardiograph leads with correspondent synthesized one or more electrocardiograph leads wherein said step of synthesizing one or more 12-lead electrocardiograph leads further comprises the step of synthesizing one or more 12-lead electrocardiograph leads by applying a recalled synthesis matrix and a recalled accuracy factor associated with said recalled synthesis matrix to an identified subset of 12-lead electrocardiograph leads formed by an attached subset of the full electrode set.

23. The method of claim 22, wherein said step of synthesizing one or more 12-lead electrocardiograph leads further comprises the steps of:

synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads; and

in response to user-defined parameters, synthesizing one or more 12-lead electrocardiograph leads from a second subset, different than said first subset, of a patient'"'"'s physically present 12-lead electrocardiograph leads.

24. The method of claim 22, wherein said step of comparing further comprises the step of simultaneously displaying said generated one or more electrocardiograph leads with correspondent synthesized one or more electrocardiograph leads.

25. The method of claim 22, wherein said step of comparing further comprises the step of automatically comparing said generated one or more electrocardiograph leads with correspondent synthesized one or more electrocardiograph leads.

26. A system for synthesizing a 12-lead electrocardiograph utilizing fewer than the 12 leads provided by a full electrode set, said system comprising:

means for attaching a subset of the full electrode set to a patient;

means for identifying a subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set;

means, responsive to said identified subset of 12-lead electrocardiograph leads, for recalling a synthesis matrix;

means, responsive to said recalled synthesis matrix, for recalling an accuracy factor associated with said recalled synthesis matrix; and

means for synthesizing one or more 12-lead electrocardiograph leads by applying said recalled synthesis matrix and said recalled accuracy factor associated with said recalled synthesis matrix to said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

27. The system of claim 26, wherein said means for recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset further comprises:

means for designating a patient profile; and

means for recalling a patient-independent synthesis matrix associated with both said designated patient profile and said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

28. The system of claim 26, wherein said means for recalling said accuracy factor associated with said recalled synthesis matrix further comprises means for recalling an accuracy factor indicative of the accuracy of each individual synthesized lead to be generated by the utilization of said recalled synthesis matrix.

29. The system of claim 28, wherein said means for recalling said accuracy factor indicative of the accuracy of each individual synthesized lead to be generated by the utilization of said recalled synthesis matrix further comprises means for recalling a standard deviation of said each representative individual synthesized lead from correspondent actual leads in a database utilized to generate said synthesis.

30. The system of claim 28, wherein said means for recalling said accuracy factor indicative of the accuracy of each individual synthesized lead to be generated by the utilization of said recalled synthesis matrix further comprises means for recalling an average accuracy factor drawn upon a standard deviation of said each representative individual synthesized lead from correspondent actual leads in a database utilized to generate said synthesis matrix.

31. The system of claim 26, wherein said means for recalling a synthesis matrix further comprises means for recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

32. The system of claim 31, wherein said means for recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set further comprises means for recalling a patient-independent synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

33. The system of claim 31, wherein said means for recalling a synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set further comprises means for recalling a patient-dependent synthesis matrix associated with said identified subset of 12-lead electrocardiograph leads formed by said attached subset of the full electrode set.

34. A system for quickly and efficiently producing multiple syntheses of 12-lead electrocardiographs utilizing fewer than the 12 leads provided by a full electrode set, said system comprising:

means for synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads; and

means, responsive to user-defined parameters, for synthesizing one or more 12-lead electrocardiograph leads from a second subset, different than said first subset, of a patient'"'"'s physically present 12-lead electrocardiograph leads.

35. The system of claim 34, wherein said means for synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises:

means for attaching a first subset of the full electrode set to said patient;

means for identifying a first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set; and

means for synthesizing one or more 12-lead electrocardiograph leads from said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

36. The system of claim 35, wherein said means for synthesizing from said identified first subset further comprises:

means, responsive to said identified first subset of 12-lead electrocardiograph leads, for recalling a first synthesis matrix; and

means for synthesizing one or more 12-lead electrocardiograph leads by applying said recalled first synthesis matrix to said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

37. The system of claim 36, wherein said means for recalling a first synthesis matrix further comprises means for recalling a first patient-independent synthesis matrix associated with said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

38. The system of claim 36, wherein said means for recalling a first synthesis matrix further comprises means for recalling a first patient-dependent synthesis matrix associated with said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

39. The system of claim 35, wherein said means for synthesizing from said identified first subset further comprises:

means for designating a patient profile;

means for recalling a first patient-independent synthesis matrix associated with both said designated patient profile and said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set; and

means for synthesizing one or more 12-lead electrocardiograph leads by applying said recalled first patient-independent synthesis matrix associated with both said designated patient profile and said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set to said identified first subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

40. The system of claim 34, wherein said means for synthesizing one or more 12-lead electrocardiograph leads from a second subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises:

means for attaching a second subset, different from said attached first subset, of the full electrode set to said patient;

means for identifying a second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set; and

means for synthesizing one or more 12-lead electrocardiograph leads from said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

41. The system of claim 40, wherein said means for synthesizing from said identified second subset further comprises:

means, responsive to said identified second subset of 12-lead electrocardiograph leads, for recalling a second synthesis matrix; and

means for synthesizing one or more 12-lead electrocardiograph leads by applying said recalled second synthesis matrix to said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

42. The system of claim 40, wherein said means for synthesizing from said identified second subset further comprises:

means for designating a patient profile;

means for recalling a second patient-independent synthesis matrix associated with both said designated patient profile and said identified second subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set; and

means for synthesizing one or more 12-lead electrocardiograph leads by applying said recalled second patient-independent synthesis matrix associated with both said designated patient profile and said identified second subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set to said identified second subset of 12-lead electrocardiograph leads formed by said attached first subset of the full electrode set.

43. The system of claim 41, wherein said means for recalling a second synthesis matrix further comprises means for recalling a second patient-independent synthesis matrix associated with said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

44. The system of claim 41, wherein said means for recalling a second synthesis matrix further comprises means for recalling a second patient-dependent synthesis matrix associated with said identified second subset of 12-lead electrocardiograph leads formed by said attached second subset of the full electrode set.

45. The system of claim 34, wherein said means for synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises means for synthesizing one or more 12-lead electrocardiograph leads by applying a recalled synthesis matrix and a recalled accuracy factor associated with said recalled synthesis matrix to an identified subset of 12-lead electrocardiograph leads formed by an attached subset of the full electrode set.

46. The system of claim 34, wherein said means for synthesizing one or more 12-lead electrocardiograph leads from a second subset of a patient'"'"'s physically present 12-lead electrocardiograph leads further comprises means for synthesizing one or more 12-lead electrocardiograph leads by applying a recalled synthesis matrix and a recalled accuracy factor associated with said recalled synthesis matrix to an identified subset of 12-lead electrocardiograph leads formed by an attached subset of the full electrode set.

47. A system for assessing the accuracy of synthesized electrocardiograph leads, said system comprising:

means for synthesizing one or more electrocardiograph leads;

means for attaching one or more additional electrodes to the patient;

means for generating one or more electrocardiograph leads from said attached one or more additional electrodes; and

means for comparing said generated one or more electrocardiograph leads with correspondent synthesized one or more electrocardiograph leads wherein said means for synthesizing one or more 12-lead electrocardiograph leads further comprises means for synthesizing one or more 12-lead electrocardiograph leads by applying a recalled synthesis matrix and a recalled accuracy factor associated with said recalled synthesis matrix to an identified subset of 12-lead electrocardiograph leads formed by an attached subset of the full electrode set.

48. The system of claim 47, wherein said means for synthesizing one or more 12-lead electrocardiograph leads further comprises:

means for synthesizing one or more 12-lead electrocardiograph leads from a first subset of a patient'"'"'s physically present 12-lead electrocardiograph leads; and

means, responsive to user-defined parameters, for synthesizing one or more 12-lead electrocardiograph leads from a second subset, different than said first subset, of a patient'"'"'s physically present 12-lead electrocardiograph leads.

49. The system of claim 47, wherein said means for comparing further comprises means for simultaneously displaying said generated one or more electrocardiograph leads with correspondent synthesized one or more electrocardiograph leads.

50. The system of claim 47, wherein said means for comparing further comprises means for automatically comparing said generated one or more electrocardiograph leads with correspondent synthesized one or more electrocardiograph leads.