Diagnostic apparatus utilizing radiation interaction with biological tissue
First Claim
1. Diagnostic apparatus comprising:
- (a) a source (1) of probing electromagnetic radiation(b) means (2) for transmitting the output from the probing radiation source (1) to biological tissue (3) to be examined(c) means (4,
41) for detecting probing radiation reflected from the tissue (3) and stimulated radiation resulting from excitation of the tissue (3) by the probing radiation(d) processing means (5-9) responsive to the reflected and stimulated radiations to produce a signal for diagnosis of the condition of the tissue, and(e) means (15,
16) for regulating the intensity of the probing radiation including a feedback circuit (16, 17,
18) for controlling the regulating means (15) and responsive to the intensity of the reflected and stimulated radiation.
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Abstract
A diagnostic apparatus comprises a source (1) of probing electromagnetic radiation and means (2) for transmitting the output from the probing radiation source (1) to biological tissue (3) to be examined. The apparatus also comprises means (4, 41) for detecting probing radiation reflected from the tissue (3) and stimulated radiation resulting from excitation of the tissue (3) by the probing radiation. A processing means (5-9) responsive to the reflected and stimulated radiations to produce a signal for diagnosis of the condition of the tissue and means (15, 16) for regulating the intensity of the probing radiation including a feedback circuit (16, 17, 18) for controlling the regulating means (15) and responsive to the intensity of the probing, reflected and/or stimulated radiation are also included.
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Citations
44 Claims
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1. Diagnostic apparatus comprising:
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(a) a source (1) of probing electromagnetic radiation (b) means (2) for transmitting the output from the probing radiation source (1) to biological tissue (3) to be examined (c) means (4,
41) for detecting probing radiation reflected from the tissue (3) and stimulated radiation resulting from excitation of the tissue (3) by the probing radiation(d) processing means (5-9) responsive to the reflected and stimulated radiations to produce a signal for diagnosis of the condition of the tissue, and (e) means (15,
16) for regulating the intensity of the probing radiation including a feedback circuit (16, 17,
18) for controlling the regulating means (15) and responsive to the intensity of the reflected and stimulated radiation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37)
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- 38. A method of diagnosing the condition of biological tissue (3), comprising the steps of impinging electromagnetic radiation on the tissue, detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, processing the reflected and stimulated radiations to produce a signal identifying the condition of the tissue, monitoring the intensity of the probing radiation by sensing a fraction of the reflected and stimulated radiations, and regulating the intensity of the probing radiation in response to the intensity of said fraction.
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41. A method of defining the state of biological tissue (3), using apparatus including a source of probing electromagnetic radiation, means for transmitting an output from the source of probing electromagnetic radiation to biological tissue to be examined, and means for detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, and including the steps of:
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(a) transmitting a probing signal comprising probing radiation from the source of probing electromagnetic radiation to biological tissue to be examined, (b) detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, (c) modulating amplitude, frequency and temporal characteristics of the probing signal, and (d) step-by-step analysis, and amplitude, frequency and temporal characteristics processing of the tissue reflected probing signal and the signal stimulated by the probing irradiation, and of variations invoked by modulation of the characteristics of the probing signal, to define the state of the biological tissue.
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42. A method of defining the state of biological tissue (3), using apparatus including a source of probing electromagnetic radiation, means for transmitting an output from the source of probing electromagnetic radiation to biological tissue to be examined, and means for detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, and including the steps of:
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(a) transmitting a probing signal comprising probing radiation from the source of probing electromagnetic radiation to biological tissue to be examined, (b) detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, (c) modulating amplitude, frequency and temporal characteristics of external means, regulating intensity of the stimulated radiation, and (d) step-by-step analysis, and amplitude, frequency and temporal characteristics processing of the tissue reflected probing signal and the signal stimulated by the probing irradiation, and of variations invoked by modulation of the characteristics of the external means, to define the state of the biological tissue.
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43. A method of defining the state of biological tissue (3), using apparatus including a source of probing electromagnetic radiation, means for transmitting an output from the source of probing electromagnetic radiation to biological tissue to be examined, and means for detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, and including the steps of:
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(a) transmitting a probing signal comprising probing radiation from the source of probing electromagnetic radiation to biological tissue to be examined and the probing signal further comprising a fixed band wave scanning in accordance with at least one of definite and random control, (b) detecting probing radiation reflected from the tissue and stimulated radiation resulting form excitation of the tissue by the probing radiation, and (c) step-by-step dynamic analysis of the stimulated signal characteristic frequencies and amplitude peak-value displacements due to the probing signal fixed band wave scanning to define the state of the biological tissue.
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44. A method of defining the state of biological tissue (3) and radiant therapy for treating the tissue, using apparatus including a source of probing electromagnetic radiation, means for transmitting an output from the source of probing electromagnetic radiation to biological tissue to be examined, means for detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, a radioactive source for performing radiant therapy, and means for tissue oxygenation stimulation, and the process of defining the state of biological tissue including the steps of:
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(a) transmitting a probing signal comprising probing radiation from the source of probing electromagnetic radiation to biological tissue to be examined, (b) detecting probing radiation reflected from the tissue and stimulated radiation resulting from excitation of the tissue by the probing radiation, the process of radiant therapy including the steps of; (c) performing oxygenation stimulation to reach maximal oxygen concentration in tissue with subsequent radiant therapy and (d) repeating steps a) through c) until the tissue is diagnosed as normal.
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Specification