High affinity TGF.beta. nucleic acid ligands and inhibitors
First Claim
Patent Images
1. A purified and isolated non-naturally occurring RNA ligand to TGFβ
- 1 wherein said ligand is selected from the group consisting of the sequences set forth in Table 3 (SEQ ID NOS;
6-143).
2 Assignments
0 Petitions
Accused Products
Abstract
Methods are described for the identification and preparation of high-affinity nucleic acid ligands to TGFβ. Included in the invention are specific RNA ligands to TGFβ1 identified by the SELEX method. Also included are RNA ligands that inhibit the interaction of TGFβ1 with its receptor.
-
Citations
1 Claim
-
1. A purified and isolated non-naturally occurring RNA ligand to TGFβ
- 1 wherein said ligand is selected from the group consisting of the sequences set forth in Table 3 (SEQ ID NOS;
6-143).
- 1 wherein said ligand is selected from the group consisting of the sequences set forth in Table 3 (SEQ ID NOS;
Specification