Portable oxygen based drug delivery system

• US 6,125,844 A
• Filed: 04/30/1998
• Issued: 10/03/2000
• Est. Priority Date: 04/30/1998
• Status: Expired due to Fees

• Current Assignee: Westwood Biomedical, Inc.
• Original Assignee: Westwood Biomedical, Inc.
• Inventors: Samiotes, Nicholas G.
• Primary Examiner(s): Lewis, Aaron J.
• Assistant Examiner(s): MITCHELL, TEENA KAY
• Application Number:
  US09/071,354
• Time in Patent Office: 887 Days
• Field of Search: 128/200.12, 128/200.14, 128/200.23, 128/200.21, 128/203.12, 128/203.14, 128/203.15, 128/203.21, 128/205.21, 128/200.22
• US Class Current: 128/200.23
• CPC Class Codes: A61M 11/06 of the injector type
• CPC Class Codes: A61M 15/0065 Inhalators with dosage or measuring devices A61M15/0028 takes precedence; dosage devices incorporated in aerosol cans B65D83/52
• CPC Class Codes: A61M 15/008 Electronic counters
• CPC Class Codes: A61M 15/0091 mechanically breath-triggered
• CPC Class Codes: A61M 15/0093 without arming or cocking, e.g. acting directly on the delivery valve
• CPC Class Codes: A61M 15/0098 Activated by exhalation
• CPC Class Codes: A61M 2202/064 Powder
• CPC Class Codes: A61M 2205/8225 using incorporated gas cartridges for the driving gas

Abstract

Apparatus for portable gas-assisted dispensing of medication not using a fluorocarbon propellant. The apparatus comprises a pressurized supply of gas containing therapeutic gas or mixture of therapeutic gases, and one or more drugs mixed therein, connected to a pressure regulator, wherein the pressure regulator is connected to a gas release switch which is connected to a breath activator. The breath activator is connected to an aspiration chamber, whereby in use when a patient inhales from the aspiration chamber, the inhalation causes the breath activator to engage with the gas release switch to release the therapeutic gas/drug mixture into the aspiration chamber, wherein the therapeutic gas and drug in the aspiration chamber are simultaneously delivered to a patient during inhalation. Alternatively, medication can be stored in a separate drug reservoir adjacent the pressurized supply of therapeutic gas, which medication is drawn into the aspiration chamber by a venturi assembly. In addition, the breath activator can respond to exhalation to measure and record exhalation flow rate.

Claims

1. Apparatus for portable gas-assisted dispensing of medication, said apparatus employing a fluorocarbon-free compressed gas propellant, said apparatus including an upper section comprising an inhaler mouthpiece, a dose release valve and an air/therapeutic gas chamber, said chamber containing a valve connected to an activation lever, said valve controlling the release of therapeutic gas to said mouthpiece as well as containing a device for pumping air from said air/therapeutic gas chamber to said mouthpiece, said valve connected to said activation lever which lever when depressed causes said valve to release said therapeutic gas and to simultaneously convey said air to said mouthpiece, said apparatus also including a lower section containing a pressurized therapeutic gas selected from the group consisting of oxygen, air, carbon dioxide, nitrous oxide, nitrogen, nitric oxide, helium and a mixture thereof, and a medication chamber containing medication connected to said dose release valve and said pressurized therapeutic gas connected to and delivering therapeutic gas to said air/therapeutic gas chamber, wherein said apparatus, upon depression of said activation lever, provides an air/therapeutic gas/medication mixture to said mouthpiece for dispensing thereof.

2. The apparatus of claim 1, wherein said upper section includes an atomizer tube connected to said air/therapeutic gas chamber which atomizer tube atomizes said air/therapeutic gas/medication mixture prior to release in said mouthpiece.

3. The apparatus of claim 1, further including a timer mechanism which mechanism controls said activation lever from engaging with said valve to thereby regulate the release of said air/therapeutic gas/medication mixture over a selected period of time.

4. The apparatus of claim 1 wherein said upper section and said lower sections can be separated from one another for reuse or disposal.

5. Apparatus for portable gas-assisted dispensing of medication, said apparatus employing a fluorocarbon-free compressed gas propellant, said apparatus including an upper section comprising an inhaler mouthpiece, a dose release valve and an air/therapeutic gas chamber, said chamber containing a valve connected to breath activator, said valve controlling the release of therapeutic gas to said mouthpiece as well as containing a device for pumping air from said air/therapeutic gas chamber to said mouthpiece, said valve connected to said breath activator which activated by inhalation at said inhaler mouthpiece causes said valve to release said therapeutic gas and to simultaneously convey said air to said mouthpiece, said apparatus also including a lower section containing a pressurized therapeutic gas selected from the group consisting of oxygen, air, carbon dioxide, nitrous oxide, nitrogen, nitric oxide, helium and a mixture thereof, and a medication chamber containing medication connected to said dose release valve and said pressurized therapeutic gas connected to and delivering therapeutic gas to said air/therapeutic gas chamber, wherein said apparatus, upon activation of said breath activator delivers an air/therapeutic gas/medication mixture to said mouthpiece for dispensing thereof.

6. The apparatus of claim 5, wherein said upper section includes an atomizer tube connected to said air/therapeutic gas chamber which atomizer tube atomizes said air/therapeutic gas/medication mixture prior to release in said mouthpiece.

7. The apparatus of claim 5, further including a timer mechanism which mechanism controls said breath activator from engaging with said valve to thereby regulate the release of said air/therapeutic gas/medication mixture over a selected period of time.

8. The apparatus of claim 5 wherein said upper section and said lower sections can be separated from one another for reuse or disposal.

9. Apparatus for portable gas-assisted dispensing of medication, said apparatus employing a fluorocarbon-free pressurized gas propellant, said apparatus including an upper section comprising an inhaler mouthpiece, a dose release valve and a therapeutic gas chamber, said chamber containing a valve connected to an activation lever, said valve controlling the release of therapeutic gas to said mouthpiece, said valve connected to said activation lever which lever when depressed causes said valve to release said therapeutic gas to said mouthpiece, said apparatus also including a lower section containing a pressurized therapeutic gas selected from the group consisting of oxygen, air, carbon dioxide, nitrous oxide, nitrogen, nitric oxide, helium and a mixture thereof and a medication chamber containing medication connected to said dose release valve and said pressurized therapeutic gas connected to and delivering therapeutic gas to said therapeutic gas chamber, wherein said apparatus, upon depression of said activation lever, provides a therapeutic gas/medication mixture to said mouthpiece for dispensing thereof.

10. The apparatus of claim 9, wherein said upper section includes an atomizer tube connected to said air/therapeutic gas chamber which atomizer tube atomizes said air/therapeutic gas/medication mixture prior to release in said mouthpiece.

11. The apparatus of claim 9, further including a timer mechanism which mechanism controls said breath activator from engaging with said valve to thereby regulate the release of said air/therapeutic gas/medication mixture over a selected period of time.

12. The apparatus of claim 9 wherein said upper section and said lower sections can be separated from one another for reuse or disposal.

13. Apparatus for portable gas-assisted dispensing of medication, said apparatus employing a fluorocarbon-free pressurized gas propellant, said apparatus including an upper section comprising an inhaler mouthpiece, a dose release valve and an air/therapeutic gas chamber, said air/therapeutic gas chamber containing a valve connected to breath activator, said valve controlling the release of therapeutic gas to said mouthpiece, said valve connected to said breath activator which when activated by inhalation at said inhaler mouthpiece causes said valve to release said therapeutic gas to said mouthpiece, said apparatus also including a lower section containing a pressurized therapeutic gas selected from the group consisting of oxygen, air, carbon dioxide, nitrous oxide, nitrogen, nitric oxide, helium and a mixture thereof, and a medication chamber containing medication connected to said dose release valve, and said pressurized therapeutic gas connected to and delivering therapeutic gas to said air/therapeutic gas chamber, wherein said apparatus, upon activation of said breath activator delivers an air/therapeutic gas/medication dose mixture to said mouthpiece for dispensing thereof.

14. The apparatus of claim 13, further including a low dose indicator which indicator measures and records the number of said air/therapeutic gas/medication dose mixtures dispensed.

15. The apparatus of claim 14 wherein said breath activator is connected to a strain gauge wherein said breath activator further responds to exhalation flow and said strain gauge measures said exhalation flow.