Automatic capture verification in multisite cardiac pacing

• US 6,128,535 A
• Filed: 12/05/1997
• Issued: 10/03/2000
• Est. Priority Date: 12/05/1997
• Status: Expired due to Term

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Maarse, Albert
• Primary Examiner(s): Kamm, William E.
• Application Number:
  US08/986,319
• Time in Patent Office: 1,033 Days
• Field of Search: 607/27, 607/28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

An implantable device and method of cardiac stimulation that automatically verifies capture and a threshold effectiveness of stimulation of a cardiac stimulator. During predetermined periods, the device utilizes 2 or more pacing/sensing electrodes positioned within an electrically continuous area of the heart, wherein one electrode is used to provide a pacing stimulus while the other electrode or electrodes are used to verify capture or a threshold effective strength. A predetermined blanking period is provided to avoid detection of the electrical stimulus transmitted to one electrode from a pulse generator. After expiration of the predetermined blanking period the remaining electrodes detect depolarization of the surrounding tissue.

Claims

1. A method for verifying capture of a stimulation pulse delivered to a pre-selected chamber of a patient'"'"'s heart, by a cardiac rhythm management device of the type having means for sensing cardiac electrogram signals, a programmable controller coupled to receive the sensed electrogram signals, and stimulation means controlled by the controller for applying cardiac stimulation pulses to a patient'"'"'s heart in response to control signals from the controller in accordance with predetermined parameters, wherein the stimulation pulse is delivered to the preselected chamber on a demand or continuous basis, said method comprising the steps of:

(a) positioning at least three electrodes in at least one of an electrically continuous area of the heart'"'"'s atriums and an electrically continuous area of the heart'"'"'s ventricles;

(b) setting predetermined parameters of the cardiac rhythm management device;

(c) delivering stimulation pulses in accordance with the predetermined parameters;

(d) transmitting from the cardiac rhythm management device a test stimulation pulse having a predetermined output energy to a predetermined first electrode; and

(e) sensing for a depolarization waveform at at least two of the other electrodes, wherein a sensed depolarization indicates capture.

2. The method as recited in claim 1, further including the steps of:

i) during delivery of stimulation pulses in accordance with the predetermined parameters, storing in memory of the programmable controller a first time relation between a depolarization detection on at least two of the other electrodes;

ii) after transmitting said test stimulation pulse, storing in memory of the programmable controller a second time relation between a second depolarization detection on at least two of the other electrodes;

then

iii) comparing said stored first and second timing relations wherein a difference between the first and second relation that exceed a predetermined amount indicates a change in an effectiveness of the stimulation pulses.

3. The method as recited in claim 2, wherein the steps of storing the first and second timing relations further includes the step of determining the first and second time relation from a set of relative times, calculated for each of the detecting electrodes, with respect to a time between the depolarization detection on at least two of the other electrodes over the same cardiac cycle.

4. The method as recited in claim 1, wherein the step of transmitting the test stimulation pulse further includes calculating an appropriate time for delivering the test stimulation pulse, said appropriate time being dependant upon a cardiac cycle length, and wherein the test stimulation pulse is transmitted with sufficient time to detect depolarization.

5. The method as recited in claim 1, further including the step of reducing the output energy and repeating steps c-e if a depolarization is sensed at least two of the other electrodes.

6. The method as recited in claim 1, and further including the step of identifying a smallest output energy wherein a depolarization waveform is sensed, thereby reducing unnecessary power drain of a power supply of the cardiac rhythm management device.

7. A method for verifying capture of a stimulation pulse delivered to a pre-selected chamber of a patient'"'"'s heart, by a cardiac rhythm management device of the type having means for sensing cardiac electrogram signals, a programmable controller coupled to receive the sensed electrogram signals, and stimulation means controlled by the controller for applying cardiac stimulation pulses to a patient'"'"'s heart in response to control signals from the controller in accordance with predetermined parameters, wherein the stimulation pulse is delivered to the preselected chamber on a demand or continuous basis, said method comprising the steps of:

(a) positioning a plurality of electrodes in at least one of an electrically continuous area of a heart'"'"'s atriums and an electrically continuous area of the heart'"'"'s ventricles;

(b) setting predetermined parameters of the cardiac rhythm management device;

(c) delivering stimulation pulses in accordance with the predetermined parameters;

(d) transmitting from the cardiac rhythm management device a test stimulation pulse having a predetermined output energy to a predetermined electrode; and

(e) sensing for a depolarization waveform at predetermined electrodes, wherein a sensed depolarization indicates capture.

8. The method as recited in claim 7, further including the steps of:

(i) during delivery of stimulation pulses in accordance with the predetermined parameters, storing in memory of the programmable controller a first time relation between sensing a first depolarization waveform on at least two electrodes;

(ii) after transmitting said test stimulation pulse, storing in memory of the controller a second time relation between sensing a second depolarization waveform on at least two electrodes;

(iii) comparing said first and second timing relations wherein a difference between the first and second timing relations indicates a change in an effectiveness of the stimulation pulses.

9. The method as recited in claim 8, wherein the steps of storing the first and second timing relations further includes the step of determining the first and second time relation from a set of relative times, calculated for each of the detecting electrodes, with respect to a time between the depolarization detection on at least two electrodes over the same cardiac cycle.

10. The methods as recited in claim 7, wherein the step of transmitting the test stimulation pulse further includes calculating an appropriate time for delivering the test stimulation pulse, said appropriate time being dependant upon a cardiac cycle length, and wherein the test stimulation pulse is transmitted with sufficient time to detect depolarization.

11. The method as recited in claim 7, and further including the step of identifying a smallest output energy wherein a depolarization waveform is sensed, thereby reducing unnecessary power drain of a power supply of the cardiac rhythm management device.