Roller bottle having pitted or cratered inner surface for cell growth
First Claim
1. A roller bottle for use in a method of culturing microbiological material, comprising a rough or uneven polymeric inner cell growth surface added to or formed as an integral part of the bottle, said inner growth surface being pitted or cratered to provide said rough or uneven growth surface and being arranged for contact with microbiological material being cultured.
2 Assignments
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Accused Products
Abstract
A roller bottle and method of culturing biological material, such as cells, using the roller bottle are disclosed. The roller bottle comprises a rough or uneven polymeric inner cell growth surface for culturing the cells. The growth surface is formed as an integral part of the roller bottle. The rough or uneven growth surface is provided by the inner growth surface being pitted or cratered to a depth of 1 mm or less. Further, the craters of the inner growth surface may be in the form of micro-cupels and measure less than 2 mm across.
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Citations
20 Claims
- 1. A roller bottle for use in a method of culturing microbiological material, comprising a rough or uneven polymeric inner cell growth surface added to or formed as an integral part of the bottle, said inner growth surface being pitted or cratered to provide said rough or uneven growth surface and being arranged for contact with microbiological material being cultured.
- 10. A method of providing a bottle with a rough or uneven growth surface for use in culturing microbiological material, comprising forming a layer of an organic polymer studded with a granular material on an inner surface of the bottle, setting the layer, and removing the granular material to leave a pitted or cratered inner surface as an integral part thereof.
Specification