Non-invasive blood pressure sensor with motion artifact reduction

• US 6,132,382 A
• Filed: 10/16/1998
• Issued: 10/17/2000
• Est. Priority Date: 10/16/1998
• Status: Expired due to Fees

• Current Assignee: Medwave, Inc.
• Original Assignee: Medwave, Inc.
• Inventors: Thede, Roger C., Curran, Timothy G., Poliac, Marius O., Archibald, G. Kent, Danielson, Orland H.
• Primary Examiner(s): Nasser, Robert L.
• Application Number:
  US09/174,164
• Time in Patent Office: 732 Days
• Field of Search: 600/485, 600/493-496, 600/500, 600/503, 600/561
• US Class Current: 600/485
• CPC Class Codes: A61B 2562/0247 Pressure sensors
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/02225 using the oscillometric method
• CPC Class Codes: A61B 5/6843 Monitoring or controlling sensor contact pressure

Abstract

A non-invasive blood pressure sensor includes a first fluid filled sensing chamber having a diaphragm. A first transducer is fluidly coupled to the first sensing chamber to sense fluid pressure within the first chamber. A flexible body conformable wall surrounds the sensing chamber. The wall applies force to the artery while preventing pressure in a direction generally parallel to the artery from being applied to the sensing chamber. The flexible body conformable wall includes a second fluid filled chamber. A second transducer fluidly coupled to the second chamber sensing fluid pressure within the second chamber. As varying pressure is applied to the artery pressure waveforms are sensed by the first transducer. Using output signals of the first and second transducers, the sensed pressure waveform data is analyzed to derive waveform parameters from which blood pressure values are derived. The effects of motion artifacts are reduced by the use of signals from both the first and second transducers.

Claims

1. A method for determining blood pressure of an artery having a pulse, the method comprising:

applying pressure to the artery with a flexible body comformable wall;

sensing pressure data produced by the artery via a fluid filled chamber proximate to the wall;

sensing noise data associated with the wall;

correcting the pressure data based upon the noise data to produce corrected pressure data;

deriving a plurality of parameters from the corrected pressure data; and

determining a blood pressure value based upon the parameters.

2. The method of claim 1 wherein sensing noise data comprises sensing pressure applied to the artery.

3. A method for determining blood pressure of an artery, the method comprising:

applying pressure to the artery with a flexible body conformable wall so that the artery exhibits a plurality of pressure waveforms;

producing sensed pressure waveform data representing each of the plurality of pressure waveforms via a fluid filled chamber proximate to the wall;

producing noise data sensed in the wall which is representative of noise contained in the pressure waveforms;

correcting the sensed pressure waveform data based on the noise data to produce corrected pressure waveform data;

deriving a plurality of parameters from the corrected pressure waveform data; and

determining a blood pressure value based upon the parameters.

4. A non-invasive blood pressure measurement device, the measurement device comprising:

a flexible, body conformable wall for applying pressure to an artery so that the artery exhibits pressure data;

first sensing means for sensing the pressure data where the first sensing means includes a constant volume, fluid-filled chamber and a first pressure sensor;

second sensing means for sensing noise data associated with the body conformable wall;

signal producing means connected to the first and second sensing means for producing output signals corresponding to the sensed pressure data; and

processing means for receiving the output signals from the signal producing means, for deriving a plurality of parameters using sensed pressure corrected to remove noise and for determining a blood pressure value using the derived parameters.

5. The measurement device of claim 4 wherein the first and second sensing means are mounted on a sensor interface assembly which is pivotally connected to a housing.

6. A non-invasive blood pressure measurement system comprising:

means for applying pressure to an artery with a flexible body comformable wall;

means for sensing pressure from the artery over time while the pressure is applied to the artery to generate pressure data;

means for sensing noise associated with the wall; and

means for deriving a pressure value based upon a waveform analysis of the pressure data as corrected with the noise data.

7. A method of determining blood pressure, the method comprising:

applying pressure to an artery with a flexible body comformable wall;

sensing pressure over time via a fluid filled chamber proximate to the wall while pressure is applied to the artery to generate pressure waveform data for pressure waveforms representing a plurality of beats;

sensing noise in the wall over time;

correcting the waveform data to remove the sensed noise;

detecting onset of the beats from the waveform data;

extracting waveform parameters using a detected onset of one of the beats; and

determining a blood pressure value based upon the waveform parameters.

8. A method for determining blood pressure of an artery having a pulse, the method comprising:

applying pressure to the artery with a flexible body comformable wall;

sensing pressure data produced by the artery via a fluid filled chamber proximate to the wall;

correcting the pressure data by removing noise components associated with motion artifacts sensed in the wall;

deriving a plurality of parameters from the corrected pressure data; and

determining a blood pressure value based upon the plurality of parameters and a stored set of coefficients.

9. A device for external measurements of blood pressure in an underlying artery surrounded by tissue of a patient, the device comprising:

a flexible body comformable wall;

first sensing means includes a constant volume fluid-filled chamber which proximate to and isolated from the wall for sensing blood pressure pulses in the underlying artery;

second sensing means associated with the wall for sensing noise arising from motion artifacts that affect the wall and first sensing means;

means for applying a variable pressure to the artery through the wall; and

means for calculating blood pressure from the sensed blood pressure pulses corrected to remove noise, based upon shape of the sensed pressure pulses within the underlying artery.

10. The device of claim 9, wherein the first sensing means includes:

a first transducer having a sensing surface;

a first flexible diaphragm for being positioned over the underlying artery; and

first interface means between the first flexible diaphragm and the sensing surface of the first transducer for transmitting pressure pulses from the first flexible diaphragm to the first transducer.

11. The device of claim 10, wherein the second sensing means includes:

a second transducer having a sensing surface;

a second flexible diaphragm; and

second interface means between the second flexible diaphragm and the sensing surface of the transducer for transmitting pressure from the second flexible diaphragm to the second transducer.

12. A device for sensing blood pressure within an underlying artery of a patient, the device comprising:

a first fluid filled sensing chamber having a diaphragm;

a first transducer fluidly coupled to the first fluid filled sensing chamber, wherein the first transducer senses fluid pressure within the first chamber;

a flexible body comformable wall proximate to the sensing chamber and isolated from the sensing chamber for applying force to the artery while preventing pressure in a direction generally parallel to the artery from being applied to the sensing chamber, the wall including a second fluid filled chamber; and

a second transducer fluidly coupled to the second fluid filled chamber wherein the second transducer senses fluid pressure within the second chamber.

13. The device of claim 12, and further comprising:

means for deriving blood pressure values based upon signals from the first and second transducers.

14. A method of determining blood pressure, the method comprising:

applying a varying pressure to an artery;

sensing pressure data produced by the artery;

associating the pressure data with beats;

arranging the beats in an order that is a function of the pressure applied to the artery as it varies with each beat;

deriving a plurality of parameters from the pressure data; and

determining a blood pressure value based upon the plurality of parameters.

15. The method of claim 14, wherein arranging the beats places the beats in order of increasing hold down pressure.

16. A method of determining blood pressure, the method comprising:

applying varying pressure to an artery;

sensing pressure data produced by the artery during a plurality of beats;

arranging the pressure data associated with the beats as a function of the pressure applied to the artery as it varies with each beat;

deriving waveform parameters from the arrange pressure data; and

determining a blood pressure value based upon the waveform parameters.

17. The method of claim 16, and further comprising:

producing a signal representative of applied pressure.

18. The method of claim 17, wherein arranging the pressure data is based upon the signal representative of applied pressure.

19. The method of claim 16, wherein arranging the pressure data comprises:

associating pressure data with beats; and

ordering the beats based upon the applied pressure during each of the beats.

20. The method of claim 19, wherein the beats are arranged in order of increasing applied pressure.

21. A method for determining blood pressure of an artery, the method comprising:

applying a varying hold down pressure to the artery;

producing sensed pressure waveform data representing each of a plurality of pressure waveforms exhibited by the artery;

ordering the sensed pressure waveform data based upon a predetermined criteria that is a function of the hold down pressure as it varies with each of the pressure waveforms exhibited by the artery;

deriving a plurality of parameters from the sensed pressure waveform data; and

determining a blood pressure value based upon the parameters.

22. The method of claim 21, and further comprising:

sensing hold down pressure applied to the artery.

23. The method of claim 21, wherein ordering the sensed pressure waveform data arranges the sensed pressure waveform data in order of increasing hold down pressure.

24. A method of determining blood pressure, the method comprising:

applying varying pressure to an artery;

sensing pressure over time while the pressure is applied to the artery to generate pressure waveform data for pressure waveforms representing a plurality of beats;

ordering the beats based upon a predetermined criteria that is a function of the pressure applied to the artery as it varies with each beat;

extracting waveform parameters trom the pressure waveform data of the ordered beats; and

determining a blood pressure value based upon the waveform parameters.

25. The method of claim 24, wherein ordering the beats places the beats in order of increasing applied pressure.

26. The method of claim 24, wherein the predetermined criteria is pressure applied during each of the beats.