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Resorcinol derivatives

  • US 6,132,740 A
  • Filed: 09/15/1998
  • Issued: 10/17/2000
  • Est. Priority Date: 09/23/1997
  • Status: Expired due to Fees
First Claim
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1. A topical pharmaceutical composition for lightening skin or reducing the pigmentation of skin in a human, comprising an amount of a compound of the formula I, ##STR3## wherein X is hydrogen;

  • OR1, wherein R1 represents hydrogen, (C1 -C6)alkyl or aryl-(C1 -C6)alkyl;

    OCOR2 wherein R2 represents (C1 -C6)alkyl, aryl-(C1 -C6)alkyl or phenyl;

    halogen;

    (C1 -C6)alkyl;

    aryl-(C1 -C6)alkyl;

    SR3 wherein R3 represents hydrogen, (C1 -C6)alkyl, or aryl-(C1 -C6)alkyl;

    or NHR1 wherein R1 is defined as above;

    n is 0; and

    the dashed line represents an optional double bond;

    or a pharmaceutically acceptable salt thereof, that is effective in lightening skin or reducing the pigmentation of skin, and a pharmaceutically acceptable carrier.

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