Methods of inhibiting neurodegerative diseases
First Claim
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1. A method of treating a neurodegenerative disease in a human patient, the method comprising administering to the patient a therapeutically effective amount of a compound that selectively inhibits a neuronal nitric oxide synthase.
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Abstract
Methods for inhibiting a nitric oxide-mediated pathological condition and a neurodegenerative disease such as Parkinson'"'"'s disease, Huntington'"'"'s disease, Alzheimers'"'"'s disease, and amyotrophic lateral sclerosis in a human patient, comprising administering an effective amount of a nitroindazole capable of inhibiting a neuronal nitric oxide synthase.
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Citations
5 Claims
- 1. A method of treating a neurodegenerative disease in a human patient, the method comprising administering to the patient a therapeutically effective amount of a compound that selectively inhibits a neuronal nitric oxide synthase.
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Current AssigneeThe General Hospital Corporation (Mass General Brigham, Inc.)
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Original AssigneeThe General Hospital Corporation (Mass General Brigham, Inc.)
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InventorsBeal, M. Flint
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Primary Examiner(s)CRIARES, THEODORE J
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Application NumberUS09/211,114Time in Patent Office673 DaysField of Search514/418, 514/415US Class Current514/418CPC Class CodesA61K 31/00 Medicinal preparations cont...A61K 31/416 condensed with carbocyclic ...
