Vasoocclusive coil

• US 6,136,015 A
• Filed: 08/25/1998
• Issued: 10/24/2000
• Est. Priority Date: 08/25/1998
• Status: Expired due to Term

• Current Assignee: Micrus Corporation (Johnson & Johnson)
• Original Assignee: Micrus Corporation (Johnson & Johnson)
• Inventors: Wilson, Peter, Ferrera, David A., Kurz, Daniel R.
• Primary Examiner(s): Buiz, Michael
• Assistant Examiner(s): Trinh, Vikki
• Application Number:
  US09/139,258
• Time in Patent Office: 791 Days
• Field of Search: 606/200, 606/108, 606/191, 606/194, 606/195, 623/1, 623/12
• US Class Current: 606/191
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers

Abstract

The vasoocclusive coil has a primary coil configuration with a helical loop at at least one end. The terminal helical loop can have a J-shaped configuration, preferably with a loop diameter of about 2 mm. The coil is preferably provided with helical loops at both ends, with helical loop at the proximal and distal ends of the coil acting as an anchor to prevent the coil from coming free from the location being treated and escaping into the vasculature. In a presently preferred embodiment both ends of the coil have a J-shape. In another presently preferred aspect, the vasoocclusive coil includes one or more loops intermediate the ends of the coil. The device is formed from a multi-stranded micro-cable having a plurality of flexible strands of a shape memory material and at least one radiopaque strand. The strands can be made of a shape memory nickel titanium alloy, that is highly flexible at a temperature appropriate for introduction into the body via a catheter, and that after placement will take on the therapeutic shape.

Claims

1. An occlusive device for use in interventional therapy and vascular surgery adapted to be inserted into a portion of a vasculature for occluding the portion of the vasculature, comprising:

a vasoocclusive coil having a primary coil configuration with a loop at least one end;

said vasoocclusive coil being formed from at least one multi-stranded micro-cable, each said multi-stranded micro-cable having a plurality of flexible strands of a resilient material, and at least one radiopaque strand to provide a radiopaque marker of the deployed configuration of said device made of the cable during vascular surgery.

2. The occlusive device of claim 1, wherein said vasoocclusive coil has a primary coil configuration with a helical loop at a distal end of the coil.

3. The occlusive device of claim 1, wherein said helical loop has a J-shape configuration.

4. The occlusive device of claim 1, wherein said vasoocclusive coil has a primary coil configuration with a helical loop at the proximal and distal ends of the coil.

5. The occlusive device of claim 4, wherein said helical loops each have a J-shape configuration.

6. The occlusive device of claim 1, wherein said helical loop has a diameter of about 2 mm.

7. The occlusive device of claim 4, wherein said helical loops each have a diameter of about 2 mm.

8. The occlusive device of claim 1, wherein said vasoocclusive coil comprises at least one loop intermediate the proximal and distal ends of the coil.

9. The occlusive device of claim 4, wherein said vasoocclusive coil comprises two loops intermediate the proximal and distal ends of the coil.

10. The occlusive device of claim 1, wherein said plurality of strands are helically wound.

11. The occlusive device of claim 1, wherein said plurality of flexible strands are parallel longitudinal strands.

12. The occlusive device of claim 1, wherein at least one of said plurality of strands comprises a super-elastic material.

13. The occlusive device of claim 1, wherein said plurality of strands are comprised of a super-elastic material.

14. The occlusive device of claim 13, wherein said super-elastic material comprises a nickel titanium alloy.

15. The occlusive device of claim 1, wherein at least one of said strands comprises a shape memory material.

16. The occlusive device of claim 1, wherein said plurality of flexible strands of a resilient material are comprised of a shape memory material.

17. The occlusive device of claim 16, wherein said shape memory material comprises a nickel-titanium alloy.

18. The occlusive device of claim 17, wherein said shape memory nickel-titanium alloy is heat treated such that the alloy is highly flexible at a temperature appropriate for introduction into the body via a catheter, and after placement, the device will take on the primary coil configuration.

19. The occlusive device of claim 15, wherein said shape memory material comprises a shape memory polymer.

20. The occlusive device of claim 1, wherein said plurality of strands comprises a plurality of exterior strands surrounding at least one interior strand.

21. The occlusive device of claim 1, wherein said plurality of strands comprises a plurality of exterior strands surrounding a central core.

22. The occlusive device of claim 1, wherein said radiopaque strand comprises at least one centrally, axially disposed radiopaque wire.

23. The occlusive device of claim 1, wherein said radiopaque wire is made of platinum.

24. The occlusive device of claim 1, wherein said radiopaque wire is made of tungsten.

25. The occlusive device of claim 1, wherein said radiopaque wire is made of gold.

26. The occlusive device of claim 1, wherein said micro-cable comprises a plurality of radiopaque strands.

27. The occlusive device of claim 1, wherein said micro-cable comprises a central core.

28. The occlusive device of claim 27, wherein said central core of said micro-cable comprises copper.

29. The occlusive device of claim 27, wherein said central core of said micro-cable comprises a copper alloy.

30. The occlusive device of claim 1, wherein said radiopaque wire is approximately from 0.0007 to 0.0015 inches in diameter.

31. The occlusive device of claim 1, wherein said strands of the micro-cable are bundled by at least one outer cover to produce a composite banded cable.

32. The occlusive device of claim 31, wherein said outer cover comprises a sheath to constrain said strands of said micro-cable about a longitudinal axis.

33. The occlusive device of claim 31, wherein said outer cover comprises an outer sheath of material to provide bending stiffness and constrain said longitudinal strands about said longitudinal axis.

34. The occlusive device of claim 33, wherein said sheath comprises a containment strand wound about said longitudinal strands.

35. The occlusive device of claim 33, wherein said sheath is made of low friction material.

36. The occlusive device of claim 33, wherein said sheath is made of a fluoropolymer.

37. The occlusive device of claim 33, wherein said sheath comprises a heat shrinkable plastic tube.

38. The occlusive device of claim 33, wherein said sheath comprises a plurality of heat shrink plastic covers placed to provide bending stiffness in said cable which varies with the position on said cable.

39. The occlusive device of claim 31, wherein said strands of the micro-cable are bundled by a plurality of bands disposed at intervals along said micro-cable to produce a composite banded cable.

40. The occlusive device of claim 39, wherein said strands are laid parallel within the composite banded cable.

41. The occlusive device of claim 39, wherein said strands are twisted within the composite banded cable.

42. The occlusive device of claim 39, wherein composite cable comprises a single inner micro-cable.

43. The occlusive device of claim 39, wherein said exterior wrapped cover is wound at varying intervals along the outside to provide variations in the torqueability and stiffness of the composite cable.

44. The occlusive device of claim 43, wherein the width of the outer cover is varied along the composite cable.

45. The occlusive device of claim 39, wherein said outer covering varies in cross section along its length to provide bending stiffness of said composite cable which varies along said composite cable.

46. The occlusive device of claim 31, wherein the number of strands and the degree to which they extend along said composite cable within the outer covering varies along said composite cable.

47. The occlusive device of claim 33, wherein outer covering comprises a plurality of layers formed of different materials in order to provide a graduated bending and stiffness characteristic over the length of the cable.

48. The occlusive device of claim 1, wherein said multi-stranded micro-cable is approximately 0.0021 to 0.0045 inches in diameter.

49. The occlusive device of claim 39, wherein said composite micro-cable comprises a plurality of micro-cables disposed within said outer cover in order to provide desired bending and strength characteristics.

50. The occlusive device of claim 49, wherein said plurality of micro-cables are helically wound within said outer cover.

51. The occlusive device of claim 49, wherein said plurality of micro-cables extend parallel and longitudinally within said outer cover.

52. The occlusive device of claim 49, wherein said plurality of micro-cables are bundled by at least one outer cover to produce said composite banded cable.

53. The occlusive device of claim 52, wherein said plurality of micro-cables are banded at intervals by a plurality of bands.