Cannula with associated filter and methods of use during cardiac surgery

• US 6,136,016 A
• Filed: 07/12/1999
• Issued: 10/24/2000
• Est. Priority Date: 11/07/1995
• Status: Expired due to Term

• Current Assignee: Edwards Lifesciences Corporation
• Original Assignee: Embol X Inc (Edwards Lifesciences Corporation)
• Inventors: Barbut, Denise, Root, Jonathan D.
• Primary Examiner(s): Buiz, Michael
• Assistant Examiner(s): TRUONG, KEVIN THAO
• Application Number:
  US09/352,546
• Time in Patent Office: 470 Days
• Field of Search: 606/200, 606/191, 606/195, 606/198, 604/96, 128/898
• US Class Current: 606/200
• CPC Class Codes: A61F 2/011 Instruments for their placement or removal
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2250/0003 having an inflatable pocket filled with fluid, e.g. liquid or gas
• CPC Class Codes: A61M 2210/127 Aorta

Abstract

Devices and methods for filtering blood. The devices generally comprise: a mesh for filtering blood flowing within a blood vessel, particularly within an artery such as the aorta; a structure adapted to open and close the mesh within the blood vessel; and a means to actuate the structure. The methods generally include the following steps: introducing a mesh into a blood vessel to entrap embolic material; adjusting the mesh, if necessary, during the course of filtration; and removing the mesh and the entrapped foreign matter from the blood vessel. Additionally, visualization techniques are used to ensure effective filtration.

Claims

1. An aortic cannula with associated filter, comprising:

a cannula having an outer surface, a distal end adapted to enter the aorta, a proximal end adapted to receive blood from a bypass-oxygenator machine, and a lumen which extends longitudinally from the proximal end to a port at the distal end;

an expansion frame insertable through the cannula which is expandable between a compressed state and a radially expanded state, wherein the expansion frame is deployable distal to the port at the distal end of the cannula; and

a continuous mesh having a substantially circular edge attached circumferentially and continuously to the expansion frame, wherein the lumen of the cannula terminates proximal of a distal tip of the mesh.

2. The cannula of claim 1, wherein the expansion frame is an inflation seal comprising a tubular balloon which encloses a chamber and is attached to the cannula.

3. The cannula of claim 1, wherein the expansion frame is an umbrella comprising a plurality of arms.

4. The cannula of claim 3, wherein the arms are pivotally connected at a distal end to the distal end of the cannula, said arms having a proximal region attached to the first edge of the mesh, wherein during use, the proximal region of the arms expands radially outward when the arms are pivoted away from the cannula.

5. The cannula of claim 1, wherein the cannula is a substantially cylindrical member which includes, at its proximal end, a fitting which is shaped for attachment to a bypass-oxygenator machine.

6. The cannula of claim 1, wherein the distal end of the cannula includes a curved portion.

7. The cannula of claim 6, wherein the distal end of the cannula is curved at an angle substantially 90°

from the proximal portion.

8. The cannula of claim 1, wherein the expansion frame is attached to the cannula by a plurality of support wires.

9. The cannula of claim 1, further comprising a flow diffuser attached to the distal end of the cannula for dispersing blood transmitted through the distal end of the cannula.

10. A method for protecting a patient from embolization, comprising the steps of:

providing a cannula having an outer surface, a distal end adapted to enter the aorta, a proximal end, a lumen which extends longitudinally from the proximal end to a port at the distal end, an expansion frame insertable through the cannula which is expandable between a compressed state and a radially expanded state, wherein the expansion frame is deployable distal to the port at the distal end of the cannula, and a continuous mesh having a substantially circular edge attached circumferentially and continuously to the expansion frame, wherein the lumen of the cannula terminates proximal of a distal tip of the mesh;

introducing the cannula into the patient'"'"'s aorta;

deploying the filter within the patient'"'"'s aorta; and

removing the blood filter and cannula from the patient'"'"'s aorta.

11. The method of claim 10, further comprising the step of performing cardiac surgery on the patient.

12. The method of claim 10, further comprising the step of performing cardiopulmonary bypass on the patient.

13. The method of claim 10, further comprising the step of blocking the aorta.

14. The method of claim 13, wherein the filter is deployed before the step of blocking the aorta.

15. The method of claim 13, wherein the filter is deployed after the step of blocking the aorta.

16. The method of claim 10, further comprising the step of unblocking the aorta.

17. The method of claim 16, wherein the step of unblocking the aorta occurs before the blood filter device is removed from the aorta.

18. The method of claim 13, wherein the step of blocking the aorta includes clamping the aorta.

19. The method of claim 10, wherein the step of blocking the aorta includes clamping the aorta.

20. The method of claim 10, wherein the filter is deployed in the ascending aorta between the heart and carotid arteries.