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Methods of reducing the levels of protoporphyrin IX in recombinant hemoglobin preparations

  • US 6,136,565 A
  • Filed: 10/18/1999
  • Issued: 10/24/2000
  • Est. Priority Date: 10/18/1996
  • Status: Expired due to Term
First Claim
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1. A method of reducing protoporphyrin IX (PIX)-containing hemoglobin in the production of recombinantly produced hemoglobin, said method comprising inserting a promoter into a host cell expressing exogenous hemoglobin, wherein said promoter causes an increase in the expression of the hemH gene.

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