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Process for preparing microparticles through phase inversion phenomena

  • US 6,143,211 A
  • Filed: 07/03/1996
  • Issued: 11/07/2000
  • Est. Priority Date: 07/21/1995
  • Status: Expired due to Term
First Claim
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1. A method for microencapsulating an agent to form a microencapsulated product, comprising:

  • dissolving a polymer in an effective amount of a solvent,dissolving or dispersing said agent in said effective amount of said solvent, wherein said polymer, said agent and said solvent form a mixture having a continuous phase and wherein the solvent is said continuous phase, andintroducing said mixture into an effective amount of a nonsolvent to cause the spontaneous formation of said microencapsulated product, wherein said solvent and said nonsolvent are miscible and 0<

    δ

    solvent -δ

    nonsolvent <

    6 wherein the nonsolvent and solvent are used in effective amounts, wherein the effective amount of nonsolvent and solvent is an effective amount when the solvent;

    nonsolvent volume ratio is between 1;

    40 and 1;

    1,000,000.

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