Pharmaceutical composition and method for immunoenhancement therapy

• US 6,143,717 A
• Filed: 11/24/1998
• Issued: 11/07/2000
• Est. Priority Date: 08/24/1993
• Status: Expired due to Term

• Current Assignee: Albert Fay Hill
• Original Assignee: Hill Medical Corporation
• Inventors: Hill, Albert Fay
• Primary Examiner(s): Weddington, Kevin E.
• Application Number:
  US09/198,354
• Time in Patent Office: 714 Days
• Field of Search: 514/3, 514/23, 514/397, 424/610, 424/686, 424/717
• US Class Current: 514/6.5
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 38/28 Insulins
• CPC Class Codes: Y02A 50/30 Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

This invention provides an immunoenhancement or immune-potentiation therapy comprising administration of potassium, insulin, glucose and, optionally, thyroid, a cholinergic agent and bicarbonate. Therapeutic compositions comprising the above components in appropriate dosages are also provided.

Claims

1. A method for immunoenhancement of an immunosuppressed mammal comprising administering to said mammal an effective amount of insulin, glucose, and potassium.

2. The method of claim 1 wherein thyroid is also administered in an amount effective to produce mild hyperthyroidism in said mammal.

3. The method of claim 1 wherein bicarbonate is also administered in an amount of at least about 1.0 mEq/kg per day.

4. The method of claim 1 in which a cholinergic agent is also administered in an amount of at least about 1.5 μ

g/kg per day.

5. The method of claim 4 in which said cholinergic agent is pilocarpine.