Multiple sensor assembly for medical electric lead

• US 6,144,866 A
• Filed: 10/30/1998
• Issued: 11/07/2000
• Est. Priority Date: 10/30/1998
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Olson, John C., Chatelle, Brenda, LaFond, Roger, Miesel, Keith A., Roberts, Jonathan P., Stetz, Eric M.
• Primary Examiner(s): WINAKUR, ERIC FRANK
• Application Number:
  US09/182,970
• Time in Patent Office: 739 Days
• Field of Search: 600/322, 600/323, 600/324, 600/325, 600/332, 600/333, 600/339, 600/341, 607/22, 607/23, 607/17, 607/21, 607/122
• US Class Current: 600/333
• CPC Class Codes: A61B 5/02154 by optical transmission
• CPC Class Codes: A61B 5/031 Intracranial pressure
• CPC Class Codes: A61B 5/14539 for measuring pH
• CPC Class Codes: A61B 5/1459 invasive, e.g. introduced into the body by a catheter A61B5/1464 takes precedence
• CPC Class Codes: A61B 5/6864 Burr holes
• CPC Class Codes: A61N 1/056 Transvascular endocardial electrode systems
• CPC Class Codes: A61N 1/36585 controlled by two or more physical parameters

Abstract

An implantable sensor assembly for use with an implantable medical device are disclosed. The sensor assembly preferably includes two or more physiologic sensors coupled to the medical device via a pair of lead conductors, or alternatively an oxygen sensor having certain features. The oxygen sensor permits more accurate and reliable measurement of oxygen saturation in blood masses flowing within the human body.

Claims

1. A body implantable medical electrical lead, comprising:

(a) a lead body having proximal and distal ends and comprising an electrically insulative material;

(b) at least first and second electrical conductors disposed within at least portions of the lead body, the conductors having at least portions of the electrically insulative material disposed therebetween; and

(c) an elongated, sensor housing attached to the lead body at a location intermediate between the lead body proximal and distal ends, the sensor housing enclosing at least one electrically powered sensor that is coupled electrically with said first and second lead conductors, the housing having proximal and distal ends, exterior surfaces, and formed of a first elongated housing member and a second elongated housing member assembled together and extending between the housing proximal and distal ends, the elongated sensor housing having an imaginary longitudinally oriented axis substantially centrally disposed within the sensor housing and extending between the proximal and distal ends thereof, a first imaginary longitudinally oriented plane extending substantially parallel to the imaginary axis and through at least portions of the sensor housing and defining first and second opposing sides, said first elongated housing member being disposed at least substantially to the first side of the first imaginary plane, said second elongated housing member being disposed at least substantially to the second side of the first imaginary plane, and said electrically powered sensor located within one of said first and second elongated housing members.

2. The body implantable medical electrical lead of claim 1, wherein the first and second housing members fit together to form an hermetically sealed sensor housing.

3. The body implantable medical electrical lead of claim 1, wherein the first elongated housing member has an oxygen sensor disposed therewithin.

4. The body implantable medical electrical lead of claim 3, wherein the oxygen sensor has first and second interior portions disposed therewithin, a light emitter being disposed within a first interior portion thereof and a light detector being disposed within a second interior portion thereof.

5. The body implantable medical electrical lead of claim 4, wherein a light transmissive first lens is disposed over the light emitter and mounted in the first elongated housing member between the exterior and first interior portion such that at least portions of light emitted by the light emitter pass through the first lens from the first interior portion to the exterior.

6. The body implantable medical electrical lead of claim 5, wherein at least the sensor housing is adapted to be implanted in a living body in operative relation with oxygenated body fluid, and a light transmissive second lens is disposed over the light detector and mounted in the first elongated housing member between the exterior and the second interior portion of the housing to enable at least portions of light emitted by the light emitter through the first lens and reflecting from oxygenated body fluid adjacent to at least portions of the first elongated housing member to pass through the second lens from the exterior to the second interior portion, the first and second lenses being separated and spaced apart from one another.

7. The body implantable medical electrical lead of claim 6, wherein a light barrier is disposed between the first and second lenses.

8. The body implantable electrical medical lead of claim 6, wherein at least one of the first and second lenses comprises one of sapphire, ruby and glass.

9. The body implantable medical electrical lead of claim 6, wherein at least one of the first and second lenses is mounted in a lens opening in a ferrule.

10. The body implantable medical electrical lead of claim 9, wherein the ferrule is one of welded and brazed to the elongated housing.

11. The body implantable medical electrical lead of claim 9, wherein at least one of the first and second lenses is brazed to the ferrule.

12. The body implantable medical electrical lead of claim 4, wherein a light barrier is disposed between the first and second interior portions.

13. The body implantable medical electrical lead of claim 4, wherein the light detector is a photodiode.

14. The body implantable medical electrical lead of claim 4, wherein the light emitter comprises at least one light emitting diode.

15. The body implantable medical electrical lead of claim 4, wherein the light emitter comprises at least first and second light emitting diodes, at least some of the light emitted by the first light emitting diode having one of a first wavelength different from one of a second wavelength emitted by the second light emitting diode.

16. The body implantable medical electrical lead of claim 4, wherein the light emitter emits at least some light in one of the infrared portion of the light spectrum and the red light portion of the light spectrum.

17. The body implantable medical electrical lead of claim 4, wherein the light detector sequentially senses light.

18. The body implantable medical electrical lead of claim 1, wherein at least one of the first and the second elongated housing members comprises a metal selected from the group consisting of titanium, stainless steel, platinum, niobium, and alloys or combinations thereof.

19. The body implantable medical electrical lead of claim 1, wherein the distal end of the sensor housing has a tip segment attachment member attached thereto.

20. The body implantable medical electrical lead of claim 1, wherein the lead further comprises at least a first electrode for stimulation of cardiac tissue disposed one of near and at the distal end of the lead body.

21. The body implantable medical electrical lead of claim 20, wherein the oxygen sensor attached to the lead body is disposed proximally of the first electrode.

22. The body implantable medical electrical lead of claim 20, wherein the first electrode is a tip electrode.

23. The body implantable medical electrical lead of claim 20, wherein the lead further includes a second electrode.

24. The body implantable medical electrical lead of claim 23, wherein the second electrode is a ring electrode.

25. The body implantable medical electrical lead of claim 1, wherein the second elongated housing member has a pressure sensor disposed therewithin.

26. The body implantable medical electrical lead of claim 25, wherein the pressure sensor is an absolute pressure sensor.

27. The body implantable medical electrical lead of claim 25, wherein the pressure sensor is a relative pressure sensor.

28. The body implantable medical electrical lead of claim 1, wherein a second imaginary longitudinally oriented plane extends substantially parallel to the imaginary axis and through at least portions of the sensor housing and defining third and fourth opposing sides, a third elongated housing member being disposed at least substantially to the third side of the imaginary plane, a fourth elongated housing member being disposed at least substantially to the fourth side of the imaginary plane.

29. The body implantable medical electrical lead of claim 28, wherein the first, second, third and fourth housing members fit together to form an hermetically sealed sensor housing.

30. An implantable medical device system, comprising:

(a) an implantable medical device;

(b) a body implantable medical electrical lead attached to the implantable medical device, the lead comprising;

(I) a lead body having proximal and distal ends and comprising an electrically insulative material, the proximal end of the lead body being attached to the implantable medical device;

(ii) at least first and second electrical conductors disposed within at least portions of the lead body, the conductors having at least portions of the electrically insulative material disposed therebetween;

(iii) an elongated, sensor housing attached to the lead body at a location intermediate between the lead body proximal and distal ends, the sensor housing enclosing at least one electrically powered sensor that is coupled electrically with said first and second lead conductors, the housing having proximal and distal ends, exterior surfaces, and formed of a first elongated housing member and a second elongated housing member assembled together and extending between the housing proximal and distal ends, the elongated sensor housing having an imaginary longitudinally oriented axis substantially centrally disposed within the sensor housing and extending between the proximal and distal ends thereof, a first imaginary longitudinally oriented plane extending substantially parallel to the imaginary axis and through at least portions of the sensor housing and defining first and second opposing sides, said first elongated housing member being disposed at least substantially to the first side of the first imaginary plane, said second elongated housing member being disposed at least substantially to the second side of the first imaginary plane, and said electrically powered sensor located within one of said first and second elongated housing members.

31. The implantable medical device system of claim 30, wherein the first and second housing members fit together to form an hermetically sealed sensor housing.

32. The implantable medical device system of claim 30, wherein the first elongated housing member has an oxygen sensor disposed therewithin.

33. The implantable medical device system of claim 32, wherein the oxygen sensor has first and second interior portions disposed therewithin, a light emitter being disposed within a first interior portion thereof and a light detector being disposed within a second interior portion thereof.

34. The implantable medical device system of claim 33, wherein a light transmissive first lens is disposed over the light emitter and mounted in the first elongated housing member between the exterior and first interior portion such that at least portions of light emitted by the light emitter pass through the first lens from the first interior portion to the exterior.

35. The body implantable medical electrical lead of claim 34, wherein at least the sensor housing is adapted to be implanted in a living body in operative relation with oxygenated body fluid, and a light transmissive second lens is disposed over the light detector and mounted in the first elongated housing member between the exterior and the second interior portion of the housing to enable at least portions of light emitted by the light emitter through the first lens and reflecting from oxygenated body fluid adjacent to at least portions of the first elongated housing member to pass through the second lens from the exterior to the second interior portion, the first and second lenses being separated and spaced apart from one another.

36. The implantable medical device system of claim 35, wherein a light barrier is disposed between the first and second lenses.

37. The implantable medical device system of claim 35, wherein at least one of the first and second lenses comprises one of sapphire, ruby and glass.

38. The implantable medical device system of claim 35, wherein at least one of the first and second lenses is mounted in a lens opening in a ferrule.

39. The implantable medical device system of claim 38, wherein the ferrule is one of welded and brazed to the elongated housing.

40. The implantable medical device system of claim 38, wherein at least one of the first and second lenses is brazed to the ferrule.

41. The implantable medical device system of claim 33, wherein a light barrier is disposed between the first and second interior portions.

42. The implantable medical device system of claim 33, wherein the light detector is a photodiode.

43. The implantable medical device system of claim 33, wherein the light emitter comprises at least one light emitting diode.

44. The implantable medical device system of claim 33, wherein the light emitter comprises at least first and second light emitting diodes, at least some of the light emitted by the first light emitting diode having one of a first wavelength different from one of a second wavelength emitted by the second light emitting diode.

45. The implantable medical device system of claim 33, wherein the light emitter emits at least some light in one of the infrared portion of the light spectrum and the red light portion of the light spectrum.

46. The implantable medical device system of claim 33, wherein the light detector sequentially senses light.

47. The implantable medical device system of claim 30, wherein at least one of the first and the second elongated housing members comprises a metal selected from the group consisting of titanium, stainless steel, platinum, niobium, and alloys or combinations thereof.

48. The implantable medical device system of claim 30, wherein the distal end of the sensor housing has a tip segment attachment member attached thereto.

49. The implantable medical device system of claim 30, wherein the lead further comprises at least a first electrode for stimulation of cardiac tissue disposed one of near and at the distal end of the lead body.

50. The implantable medical device system of claim 49, wherein the oxygen sensor attached to the lead body is disposed proximally of the first electrode.

51. The implantable medical device system of claim 49, wherein the first electrode is a tip electrode.

52. The implantable medical device system of claim 49, wherein the lead further includes a second electrode.

53. The implantable medical device system of claim 52, wherein the second electrode is a ring electrode.

54. The implantable medical device system of claim 30, wherein the second elongated housing member has a pressure sensor disposed therewithin.

55. The body implantable medical electrical lead of claim 54, wherein the pressure sensor is an absolute pressure sensor.

56. The body implantable medical electrical lead of claim 54, wherein the pressure sensor is a relative pressure sensor.

57. The body implantable medical electrical lead of claim 30, wherein a second imaginary longitudinally oriented plane extends substantially parallel to the imaginary axis and through at least portions of the sensor housing and defining third and fourth opposing sides, a third elongated housing member being disposed at least substantially to the third side of the imaginary plane, a fourth elongated housing member being disposed at least substantially to the fourth side of the imaginary plane.

58. The body implantable medical electrical lead of claim 57, wherein the first, second, third and fourth housing members fit together to form an hermetically sealed sensor housing.

59. The implantable medical device system of claim 30, wherein the implantable medical device is selected from the group consisting of a heart monitor, a therapy delivery device, a pacemaker, an implantable pulse generator, a pacer-cardio-defibrillator, an implantable cardio-defibrillator, a cardiomyo-stimulator, a nerve stimulator, a brain stimulator, a gastric stimulator and a drug delivery device.

60. A body implantable medical electrical lead having a lead body and oxygen sensor comprising an elongated sensor housing attached to the lead body, the housing having proximal and distal ends, exterior surfaces, an elongated, sensor housing attached to the lead body, the sensor housing enclosing at least one electrically powered sensor that is coupled electrically with said lead, the housing having proximal and distal ends, exterior surfaces, and formed of a first elongated housing member and a second elongated housing member assembled together and extending between the housing proximal and distal ends, the elongated sensor housing having an imaginary longitudinally oriented axis substantially centrally disposed within the sensor housing and extending between the proximal and distal ends thereof, a first imaginary longitudinally oriented plane extending substantially parallel to the imaginary axis and through at least portions of the sensor housing and defining first and second opposing sides, said first elongated housing member being disposed at least substantially to the first side of the first imaginary plane, said second elongated housing member being disposed at least substantially to the second side of the first imaginary plane, and said electrically powered sensor located within one of said first and second elongated housing members.

61. The body implantable medical electrical lead of claim 60, wherein the first and second housing members fit together to form an hermetically sealed sensor housing.

62. The body implantable medical electrical lead of claim 60, wherein the first elongated housing member includes an oxygen sensor disposed therewithin.

63. The body implantable medical electrical lead of claim 62, wherein the oxygen sensor has first and second interior portions disposed therewithin, a light emitter being disposed within a first interior portion thereof and a light detector being disposed within a second interior portion thereof.

64. The body implantable medical electrical lead of claim 63, wherein a light transmissive first lens is disposed over the light emitter and mounted in the first elongated housing member between the exterior and first interior portion such that at least portions of light emitted by the light emitter pass through the first lens from the first interior portion to the exterior.

65. The body implantable medical electrical lead of claim 64, wherein at least the sensor housing is adapted to be implanted in a living body in operative relation with oxygenated body fluid, and a light transmissive second lens is disposed over the light detector and mounted in the first elongated housing member between the exterior and the second interior portion of the housing to enable at least portions of light emitted by the light emitter through the first lens and reflecting from oxygenated body fluid adjacent to at least portions of the first elongated housing member to pass through the second lens from the exterior to the second interior portion, the first and second lenses being separated and spaced apart from one another.

66. The body implantable medical electrical lead of claim 65, wherein a light barrier is disposed between the first and second lenses.

67. The body implantable medical electrical lead of claim 65, wherein at least one of the first and second lenses comprises one of sapphire, ruby and glass.

68. The body implantable medical electrical lead of claim 65, wherein at least one of the first and second lenses is mounted in a lens opening in a ferrule.

69. The body implantable medical electrical lead of claim 68, wherein the ferrule is one of welded and brazed to the elongated housing.

70. The body implantable medical electrical lead of claim 68, wherein at least one of the first and second lenses is brazed to the ferrule.

71. The body implantable medical electrical lead of claim 63, wherein a light barrier is disposed between the first and second interior portions.

72. The body implantable medical electrical lead of claim 63, wherein the light detector is a photodiode.

73. The body implantable medical electrical lead of claim 63, wherein the light emitter comprises at least one light emitting diode.

74. The body implantable medical electrical lead of claim 63, wherein the light emitter comprises at least first and second light emitting diodes, at least some of the light emitted by the first light emitting diode having one of a first wavelength different from one of a second wavelength emitted by the second light emitting diode.

75. The body implantable medical electrical lead of claim 63, wherein the light emitter emits at least some light in one of the infrared portion of the light spectrum and the red light portion of the light spectrum.

76. The body implantable medical electrical lead of claim 63, wherein the light detector sequentially senses light.

77. The body implantable medical electrical lead of claim 60, wherein at least one of the first and the second elongated housing members comprises a metal selected from the group consisting of titanium, stainless steel, platinum, niobium, and alloys or combinations thereof.

78. The body implantable medical electrical lead of claim 60, wherein the distal end of the sensor housing has a tip segment attachment member attached thereto.

79. The body implantable medical electric lead of claim 60, wherein the second elongated housing member has a pressure sensor disposed therewithin.

80. The body implantable medical electrical lead of claim 79, wherein the pressure sensor is an absolute pressure sensor.

81. The body implantable medical electrical lead of claim 79, wherein the pressure sensor is a relative pressure sensor.

82. The body implantable medical electrical lead of claim 60, wherein a second imaginary longitudinally oriented plane extends substantially parallel to the imaginary axis and through at least portions of the sensor housing and defining third and fourth opposing sides, a third elongated housing member being disposed at least substantially to the third side of the imaginary plane, a fourth elongated housing member being disposed at least substantially to the fourth side of the imaginary plane.

83. The body implantable medical electrical lead of claim 82, wherein the first, second, third and fourth housing members fit together to form an hermetically sealed sensor housing.

84. A body implantable medical electrical lead, comprising:

(a) a lead body having proximal and distal ends and comprising an electrically insulative material;

(b) at least first and second electrical conductors disposed within at least portions of the lead body, the conductors having at least portions of the electrically insulative material disposed therebetween; and

(c) an elongated sensor housing attached to the lead body intermediate the lead body proximal and distal ends housing at least one electrically powered sensor that is coupled electrically with said first and second lead conductors, the housing having proximal and distal ends, exterior surfaces, and formed of a first elongated housing member and a second elongated housing member assembled together and extending between the housing proximal and distal ends, the elongated sensor housing having an imaginary longitudinally oriented axis substantially centrally disposed within the sensor housing and extending between the proximal and distal ends thereof, and first, second and third elongated housing members, first, second and third triaxial longitudinally oriented imaginary planes one of intersecting and substantially intersecting the imaginary axis to define respective first, second and third volumes, the first elongated housing member being disposed at least substantially in the first volume, the second elongated housing being disposed at least substantially in the second volume, and the third elongated housing being disposed at least substantially in the third volume, and said electrically powered sensor located within one of said first, second and third elongated housing members.

85. The body implantable medical electrical lead of claim 84, wherein the first, second and third housing members fit together to form an hermetically sealed sensor housing.

86. The body implantable medical electrical lead of claim 84, wherein the first elongated housing member has an oxygen sensor disposed therewithin.

87. The body implantable medical electrical lead of claim 86, wherein the oxygen sensor has first and second interior portions disposed therewithin, a light emitter being disposed within a first interior portion thereof and a light detector being disposed within a second interior portion thereof.

88. The body implantable medical electrical lead of claim 87, wherein a light transmissive first lens is disposed over the light emitter and mounted in the first elongated housing member between the exterior and first interior portion such that at least portions of light emitted by the light emitter pass through the first lens from the first interior portion to the exterior.

89. The body implantable medical electrical lead of claim 88, wherein at least the sensor housing is adapted to be implanted in a living body in operative relation with oxygenated body fluid, and a light transmissive second lens is disposed over the light detector and mounted in the first elongated housing member between the exterior and the second interior portion of the housing to enable at least portions of light emitted by the light emitter through the first lens and reflecting from oxygenated body fluid adjacent to at least portions of the first elongated housing member to pass through the second lens from the exterior to the second interior portion, the first and second lenses being separated and spaced apart from one another.

90. The body implantable medical electrical lead of claim 89, wherein a light barrier is disposed between the first and second lenses.

91. The body implantable medical electrical lead of claim 89, wherein at least one of the first and second lenses comprises one of sapphire, ruby and glass.

92. The body implantable medical electrical lead of claim 89, wherein at least one of the first and second lenses is mounted in a lens opening in a ferrule.

93. The body implantable medical electrical lead of claim 92, wherein the ferrule is one of welded and brazed to the elongated housing.

94. The body implantable medical electrical lead of claim 92, wherein at least one of the first and second lenses is brazed to the ferrule.

95. The body implantable medical electrical lead of claim 87, wherein a light barrier is disposed between the first and second interior portions.

96. The body implantable medical electrical lead of claim 87, wherein the light detector is a photodiode.

97. The body implantable medical electrical lead of claim 87, wherein the light emitter comprises at least one light emitting diode.

98. The body implantable medical electrical lead of claim 87, wherein the light emitter comprises at least first and second light emitting diodes, at least some of the light emitted by the first light emitting diode having one of a first wavelength different from one of a second wavelength emitted by the second light emitting diode.

99. The body implantable medical electrical lead of claim 87, wherein the light emitter emits at least some light in one of the infrared portion of the light spectrum and the red light portion of the light spectrum.

100. The body implantable medical electrical lead of claim 87, wherein the light detector sequentially senses light.

101. The body implantable medical electrical lead of claim 84, wherein at least one of the first and the second elongated housing members comprises a metal selected from the group consisting of titanium, stainless steel, platinum, niobium, and alloys or combinations thereof.

102. The body implantable medical electrical lead of claim 84, wherein the distal end of the sensor housing has a tip segment attachment member attached thereto.

103. The body implantable medical electrical lead of claim 84, wherein the lead further comprises at least a first electrode for stimulation of cardiac tissue disposed one of near and at the distal end of the lead body.

104. The body implantable medical electrical lead of claim 103, wherein the oxygen sensor attached to the lead body is disposed proximally of the first electrode.

105. The body implantable medical electrical lead of claim 103, wherein the first electrode is a tip electrode.

106. The body implantable medical electrical lead of claim 103, wherein the lead further includes a second electrode.

107. The body implantable medical electrical lead of claim 106, wherein the second electrode is a ring electrode.

108. The body implantable medical electrical lead of claim 84, wherein the second elongated housing member has a pressure sensor disposed therewith in.

109. The body implantable medical electrical lead of claim 108, wherein the pressure sensor is an absolute pressure sensor.

110. The body implantable medical electrical lead of claim 108, wherein the pressure sensor is a relative pressure sensor.