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Method and apparatus for delivery of therapeutic agent

  • US 6,146,358 A
  • Filed: 04/07/1992
  • Issued: 11/14/2000
  • Est. Priority Date: 03/14/1989
  • Status: Expired due to Term
First Claim
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1. In a balloon angioplasty catheter of the type comprising a catheter body and a dilatation balloon fixedly positioned along the external length of the catheter body, the improvement comprising:

  • a plurality of microcapsules on the exterior of said balloon, each of said microcapsules carrying a drug for effecting the interior of a human body lumen to prevent restenosis when said catheter is positioned and inflated therewithin such that the drug may be released from said microcapsules without requiring heating of said microcapsules;

    a mesh expandable stent defining interstices carried on the exterior of said balloon, said stent being positioned on said balloon over said microcapsules to enable the released drug to be forced outwardly between said interstices into a stenosis within the body lumen.

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