Nutritional formulations containing oligosaccharides

• US 6,146,670 A
• Filed: 12/18/1998
• Issued: 11/14/2000
• Est. Priority Date: 03/31/1997
• Status: Expired due to Term

• Current Assignee: Abbott Laboratories Incorporated
• Original Assignee: Abbott Laboratories Incorporated
• Inventors: Prieto, Pedro A., Kirchner, Stephen J., Erney, Renee M.
• Primary Examiner(s): HEGGESTAD, HELEN F
• Application Number:
  US09/216,056
• Time in Patent Office: 697 Days
• Field of Search: 426/580, 426/801, 426/658, 426/72, 426/73, 426/74
• US Class Current: 426/72
• CPC Class Codes: A23L 29/30 containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin products from apiculture A23L21/20; artificial sweetening agents A23L27/30
• CPC Class Codes: A23L 33/40 Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
• CPC Class Codes: A23V 2002/00 Food compositions, function of food ingredients or processes for food or foodstuffs
• CPC Class Codes: A23V 2250/156 Mineral combination undefined extract A23V2250/1638
• CPC Class Codes: A23V 2250/1872 Linoleic acid
• CPC Class Codes: A23V 2250/28 Oligosaccharides
• CPC Class Codes: A23V 2250/304 Choline
• CPC Class Codes: A23V 2250/70 Vitamins
• CPC Class Codes: A23V 2250/702 Vitamin A
• CPC Class Codes: A23V 2250/704 Vitamin B
• CPC Class Codes: A23V 2250/708 Vitamin C
• CPC Class Codes: A23V 2250/71 Vitamin D
• CPC Class Codes: A23V 2250/712 Vitamin E
• CPC Class Codes: Y10S 426/801 Pediatric

Abstract

A nutritional formulation containing at least one of the following oligosaccharides: from about 400 to about 3500 mg/L of 3-fucosyllactose; from about 200 to about 2200 mg/L of lacto-N-fucopentaose III; from about 100 to about 1500 mg/L of lacto-N-fucopentaose II; from about 100 to about 2500 mg/L of difucosyllactose; from about 500 to about 4500 mg/L of 2'"'"' fucosyllactose; from about 250 to about 3300 mg/L of lacto-N-fucopentaose I; from about 100 to about 900 mg/L of Lacto-N-neoTetraose; from about 50 to about 2300 mg/L of lacto-N-fucopentaose V; or from about 300 to about 2800 mg/L of lacto-N-tetraose.

Claims

1. A synthetic nutritional composition comprising:

A) at least one of the following oligosaccharides selected from the group consisting of;

from about 130 to about 3500 mg/L of 3-fucosyllactose;

from about 50 to about 2500 mg/L of difucosyllactose; and

from about 15 to about 2300 mg/L of lacto-N-fucopentaose V; and

B) edible macronutrients wherein said edible macronutrients are formulated for feeding to a human.

2. A synthetic nutritional composition comprising:

A) at least one of the following oligosaccharides selected from the group consisting of;

from about 130 to about 3500 mg/L of 3-fucosyllactose;

from about 50 to about 2500 mg/L of difucosyllactose; and

from about 15 to about 2300 mg/L of lacto-N-fucopentaose V; and

B) one or more edible macronutrients formulated for feeding to a human wherein said macronutrients are selected from the group consisting of coconut oil, soy oil, mono- and diglycerides, glucose, food grade lactose, electrodialysed whey and electrodialysed skim milk, milk whey, and soy protein.

3. A synthetic nutritional composition comprising:

A) at least one of the following oligosaccharides selected from the group consisting of;

from about 130 to about 3500 mg/L of 3-fucosyllactose;

from about 50 to about 2500 mg/L of difucosyllactose; and

from about 15 to about 2300 mg/L of lacto-N-fucopentaose V;

B) at least one of vitamins A, C, D, E, and B complex; and

C) one or more edible macronutrients formulated for feeding to a human wherein said macronutrients are selected from the group consisting of coconut oil, soy oil, mono- and diglycerides, glucose, food grade lactose, electrodialysed whey and electrodialysed skim milk, milk, whey, and soy protein.

4. A composition comprising:

A) at least one of the following oligosaccharides selected from the group consisting of;

from about 130 to about 3500 mg/L of 3-fucosyllactose;

from about 50 to 2500 mg/L of difucosyllactose and

from about 15 to about 2300 mg/L of lacto-N-fucopentaose V;

B) one or more edible macronutrients formulated for feeding to a human selected from the group consisting of coconut oil, soy oil, mono- and diglycerides, glucose, food grade lactose, electrodialysed whey, electrodialysed skim milk and milk whey;

C) one or more vitamins selected from the group consisting of A, C, D, E and B complex; and

D) one or more minerals selected from the group consisting of calcium, magnesium, manganese, sodium, potassium, phosphorus, copper, zinc, chloride, iodine, selenium and iron.

5. The composition of claim 4 wherein the oligosaccharides are present in the composition in the following amounts:

from about 800 to about 1750 mg/L of 3-fucosyllactose;

from about 200 to about 1450 mg/L of difucosyllactose;

from about 100 to about 1600 mg/L of lacto-N-fucopentaose V.

6. The composition of claim 5 wherein the oligosaccharides are present in the composition in the following amounts:

from about 1456 to about 1472 mg/L of 3-fucosyllactose;

from about 393 to about 494 mg/L of difucosyllactose;

or

from about 120 to about 154 mg/L of lacto-N-fucopentaose V.