System and method for compensating for motion artifacts in a strong magnetic field

• US 6,148,229 A
• Filed: 12/07/1998
• Issued: 11/14/2000
• Est. Priority Date: 12/07/1998
• Status: Expired due to Fees

• Current Assignee: Medrad Incorporated (Bayer AG)
• Original Assignee: Medrad Incorporated (Bayer AG)
• Inventors: Valentine, James W., Morris, G. Ronald Sr.
• Primary Examiner(s): Schaetzle, Kennedy
• Application Number:
  US09/206,316
• Time in Patent Office: 708 Days
• Field of Search: 600/509, 600/411, 600/410, 128/901
• US Class Current: 600/509
• CPC Class Codes: A61B 5/055 involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]

Abstract

A system for monitoring an ECG during a patient examination in a strong magnetic field, such as that created by an MRI machine, which eliminates motion artifacts affecting the accurate reading of the ECG. The system modulates the strong magnetic field and then generates an error correction signal substantially equal to the motion artifact signal in timed relationship with the modulated signal that is subtracted from the measured ECG signal to produce a more accurate ECG signal.

Claims

1. A method for eliminating a motion artifact signal in an electrocardiogram measurement of a subject in a strong magnetic field, comprising the steps of:

(A) producing a predetermined signal which controllably modulates the flux density of a magnetic field while performing an electrocardiogram measurement of a subject in said magnetic field to produce a first electrocardiogram signal;

(B) using said predetermined modulation signal to extract a motion artifact signal from said first electrocardiogram signal; and

(C) subtracting said extracted motion artifact signal from said first electrocardiogram signal, thereby eliminating the motion artifact signal and creating an output electrocardiogram signal free of said motion artifact signal.

2. The method of claim 1, wherein the step of producing a predetermined signal which controllably modulates the flux density of a magnetic field includes the step of exciting modulation field coils with a current proportional to said predetermined signal.

3. The method of claim 1, wherein the step of using said predetermined modulation signal to extract a motion artifact signal comprises the steps of:

generating a first sampling signal and a second sampling signal in timed relationship with said predetermined signal;

sampling said first electrocardiogram signal based upon said first sampling signal to produce a first error correction signal;

sampling said first electrocardiogram signal based upon said second sampling signal to produce a second error correction signal; and

subtracting said second error correction signal from said first error correction signal to produce said extracted motion artifact signal.

4. An apparatus for eliminating a motion artifact signal in an electrocardiogram measurement of a subject in a strong magnetic field apparatus which includes primary modulation coils for modulating said magnetic field, comprising:

(A) means for performing an electrocardiogram measurement of a subject in a magnetic field and thereby producing a first electrocardiogram signal;

(B) a modulation waveform generator for generating a predetermined modulation signal;

(C) a modulation coil driver coupled to said modulation waveform generator and to the primary field modulation coils for supplying a current proportional to said predetermined modulation signal to said primary field modulation coils;

(D) a sample and hold timing generator coupled to said modulation waveform generator for producing a first sampling signal and a second sampling signal in timed relationship with said predetermined modulation signal;

(E) a first sample and hold circuit coupled to said sample and hold timing generator and to said electrocardiogram measurement means for sampling said first electrocardiogram signal in timed relationship with said first sampling signal to produce a first error correction signal;

(F) a second sample and hold circuit coupled to said sample and hold timing generator and to said electrocardiogram measurement means for sampling said first electrocardiogram signal in timed relationship with said second sampling signal to produce a second error correction signal;

(G) a first subtraction circuit coupled to said first sample and hold circuit and to said second sample and hold circuit for subtracting said first error correction signal from said second error correction signal, thereby creating an extracted motion artifact signal; and

(H) a second subtraction circuit coupled to receive said motion artifact signal and said first electrocardiogram signal for subtracting said extracted motion artifact signal from said first electrocardiogram signal, thereby creating an output electrocardiogram signal free of said motion artifact signal.

5. The apparatus of claim 4, further comprising:

(I) a electrocardiogram monitor for displaying said output cardiogram signal; and

(J) a means for conveying said output cardiogram signal from said second subtraction circuit to said electrocardiogram monitor.

6. The apparatus of claim 4, wherein said means for performing an electrocardiogram measurement comprises:

at least three electrodes coupled to said subject;

a lead select network coupled to said electrodes; and

a differential amplifier coupled to said lead select network for producing a first electrocardiogram signal.

7. The apparatus of claim 6, further comprising:

a data transmission amplifier coupled to said second subtraction circuit;

an electrocardiogram monitor for displaying said output cardiogram signal; and

data transmission means connecting said data transmission amplifier to said electrocardiogram monitor for conveying said output cardiogram signal from said data transmission amplifier to said electrocardiogram monitor.

8. The apparatus of claim 7, wherein said lead select network, said differential amplifier, said second subtraction circuit, said data transmission amplifier, said first subtraction circuit, said first sample and hold, said second sample and hold, said sample and hold timing generator, and said modulation waveform generator are mounted within an enclosure which can be positioned next to the patient in the strong magnetic field apparatus.

9. An apparatus for eliminating a motion artifact signal in an electrocardiogram measurement of a subject in a strong magnetic field, comprising:

(A) means producing a predetermined signal to controllably modulate the flux density of a strong magnetic field;

(B) means for performing an electrocardiogram measurement of a subject in said strong magnetic field to produce a first electrocardiogram signal;

(C) means for extracting a motion artifact signal from said first electrocardiogram signal using said predetermined signal; and

(D) a subtraction circuit for subtracting said motion artifact signal from said first electrocardiogram signal, thereby creating an output electrocardiogram signal free of said motion artifact signal.