Dual site pacing system with automatic pulse output adjustment

• US 6,148,234 A
• Filed: 09/28/1998
• Issued: 11/14/2000
• Est. Priority Date: 09/28/1998
• Status: Expired due to Term

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Struble, Chester
• Primary Examiner(s): LAYNO, CARL HERNANDZ
• Application Number:
  US09/161,237
• Time in Patent Office: 778 Days
• Field of Search: 607/27, 607/28, 607/11, 607/123
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

There is provided a dual site pacing system, either bi-ventricular or bi-atrial, wherein the pacemaker looks for a signal sense during the refractory period following delivery of the pulse pair. If the threshold of either heart chamber has risen above the level of the delivered pulses, that chamber will not be captured, and will not have an inherent refractory period following delivery of the pulse pair. Under these circumstances, and where the patient has conduction delay from one chamber to the other, e.g., LBBB or RBBB, the excitation signal from the other chamber will be sensed in the non-captured chamber during the pacemaker refractory period. Such a sensing during the pacemaker refractory period is recognized to result from loss of capture, and is utilized to automatically increase pulse output back up to a safe level above threshold.

Claims

1. A cardiac pacing system with bi-ventricular pacing of a patient, comprising:

pulse means for generating a pair of concurrent pacing pulses,

lead means for delivering one of said concurrent pacing pulses to the patient'"'"'s right ventricle and one of said concurrent pacing pulses to the patient'"'"'s left ventricle, said lead means further having electrode means for sensing excitation sinals in each of said ventricles;

refractory means for timing out a refractory interval following each delivery of a said pair of concurrent pacing pulses, and sensing means electrically connected to said lead means for determining when a said excitation signal has been sensed in at least one ventricle by said electrode means during a said refractory interval; and

LOC means for indicating loss of capture in at least one of said ventricles in response to sensing one or at least ventricular excitation signal during said refractory interval;

further comprising pulse output control means for increasing the power output of at least one pulse of said pulse pair in response to an indicated loss of capture;

wherein said pulse means delivers two pulses of equal power output at substantially the same time, and said control means increases the power output of each said pulse of said pair to the same level.

2. The system as described in claim 1, wherein said control means controls said pulse mean is to deliver said pair of pulses in a timed relation so that a first of said pulses is delivered a predetermined short time interval before the second of said pulses, and said refractory means times out said refractory interval following the time of delivery of said first pulse.

3. The system as described in claim 1, wherein said lead means comprises a left lead having left distal electrode means for sensing signals in the patient'"'"'s left ventricle, and a right lead having right distal electrode means for sensing signals in the patient'"'"'s light ventricle.

4. The system as described in claim 1, wherein said sensing means comprises dual sensing channels, a first of said channels being electrically connected to said lead means to receive sensed signals from the patient'"'"'s left ventricle, and the second of said channels being electrically connected to receive signals from the patient'"'"'s right ventricle.

5. The system as described in claim 4, wherein said LOC means provides an indication of either ventricle in which an excitation was sensed, and comprising control means for increasing the power output of the pulse for delivery to either said indicated ventricle.

6. The system as described in claim 1, comprising blanking means for timing out a blanking interval following each delivery of a said pair of pulses, and wherein said refractory means comprises means for initiating said refractory interval at the end of said blanking interval.

7. The system as described in claim 6, said control means having threshold test means for decreasing said power output until loss of capture is indicated in at least one of said ventricles.

8. A dual site cardiac pacing system, providing fore delivery of substantially concurrent pacing pulses to dual sites in a patient'"'"'s heart, said system having a pacemaker and leads connected to said pacemaker for delivering pacing pulses to said sites and for obtaining cardiac senses from each of said sites, said pacemaker comprising:

pulse generator means for cyclically generating said concurrent pulses;

control means for controlling the timing and power output of said concurrent pulses;

refractory means for timing out a programmable refractory interval following each generation of said concurrent pulses;

sensing means for sensing when at least one said cardiac sense occurs at one of said sites during a said refractory interval; and

LOC means for indicating loss of capture at at least one of said sites when at least one said cardiac sense is sensed during said refractory interval;

comprising first lead means for delivery of pacing pulses to the patient'"'"'s left ventricle and for obtaining left ventricular senses, and a second lead means for delivery of pacing pulses to the patient'"'"'s right ventricle and for obtaining right ventricular senses;

wherein said control means comprises response means for responding to an indicated less of capture by increasing the output level of at least one of said concurrent pulses in response thereto;

wherein said control means has means for increasing the output level of the pulses delivered to both of said dual sites.

9. The pacing system as described in claim 8, wherein said sensing means comprises first means for sensing when, a ventricular sense occurs in the left ventricle during said refractory interval, and second means for sensing when a ventricular sense occurs in the right ventricle during said refractory interval, and said LOC means comprises VR means for indicating the ventricle in which a ventricular sense has occurred during the refractory interval (VR).

10. The pacing system as described in claim 9, wherein said response means comprises means for increasing the output level of the pulses delivered to the ventricle where a VR has been indicated.

11. The pacing system as described in claim 8, wherein said sensing means comprises means for determining a pattern of cardiac senses during the refractory interval, and said LOC means indicates loss of capture when a said pattern is determined.

12. The pacing system as described in claim 8, comprising programming means for programming said refractory interval to a value in the range of about 150-300 ms.

13. A dual site cardiac pacing system, providing for delivery of substantially concurrent pacing pulses to dual sites in a patient'"'"'s heart, said patiernt'"'"'s heart being characterized by an Intraventricular Conduction Delay of up to 300 ms, said system having a pacemaker and leads connected to said pacemaker for delivering pacing pulses to said sites and for obtaining cardiac senses from cach of said sites, said pacemaker comprising:

pulse generator means for cyclically generating said concurrent pulses;

control means for controlling the timing and power output of said concurrent pulses;

refractory means for timing out a programmable refractory interval as set to a value greater than said patient TVCD following each generation of said concurrent pulses;

sensing means for sensing when at least one said cardiac sense occurs at one of said sites during a said refractory interval;

LOC means for indicating loss of capture at at least one of said sites when at least one said cardiac sense is sensed during said refractory interval; and

response means for responding to an indicated loss of capture by increasing the output level of at least one of said concurrent pulses in response to an indicated LOC.