Method and apparatus for detecting beta radiation

• US 6,149,593 A
• Filed: 12/16/1996
• Issued: 11/21/2000
• Est. Priority Date: 12/16/1996
• Status: Expired due to Term

• Current Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Original Assignee: Trustees Of The University Of Pennsylvania (University of Pennsylvania)
• Inventors: Gonzalez-Lepera, Carlos
• Primary Examiner(s): Smith, Ruth S.
• Application Number:
  US08/767,159
• Time in Patent Office: 1,436 Days
• Field of Search: 600/431, 600/436, 250/306, 250/307, 250/308, 250/303, 250/363.01, 250/363.03
• US Class Current: 600/436
• CPC Class Codes: A61B 6/00 Apparatus or devices for radiation diagnosis; Apparatus or devices for radiation diagnosis combined with radiation therapy equipment instruments measuring radiation intensity for application in the field of nuclear medicine, e.g. in vivo counting, G01T1/161; apparatus for taking X-ray photographs G03B42/02
• CPC Class Codes: A61B 6/4258 for detecting non x-ray radiation, e.g. gamma radiation A61B6/037 takes precedence
• CPC Class Codes: G01T 1/28 with secondary-emission detectors

Abstract

A method and apparatus for detecting beta particles in the presence of high gamma background using secondary electron emission (SEE) as the primary beta particle detector. Diamond-like thin films having coefficients for SEE as high as 50 are preferably used in a small hand-held probe whereby radiolabeled malignancies as small as 3 mm in diameter can be detected. An electron multiplier amplifies the secondary electron signal for generation of an audible signal or a display indicative of the level of beta radiation passing through the air-vacuum interface of the hand-held probe.

Claims

1. A hand-held beta radiation sensor which detects beta particles emitted by an object in the presence of background gamma particles, comprising:

a portable sealed housing enclosing a vacuum, said housing including an air-vacuum interface that is substantially transparent to the passage of beta particles and through which incident beta particles emitted by said object may pass to enter said sealed housing;

a secondary electron emission (SEE) sensor disposed in said housing so as to detect said incident beta particles which have passed through said air-vacuum interface at the substantial exclusion of said gamma particles and to generate a first signal indicative of said incident beta particles; and

an amplifier which amplifies said first signal into a second signal indicative of the number of beta particles emitted by said object.

2. A beta radiation sensor as in claim 1, further comprising means responsive to said second signal for generating an audible signal representative of the number of beta particles emitted by said object.

3. A beta radiation sensor as in claim 1, further comprising means responsive to said second signal for generating a visual display representative of the number of beta particles emitted by said object.

4. A beta radiation sensor as in claim 1, wherein said air-vacuum interface comprises a thin titanium foil having a thickness of approximately 6 microns.

5. A beta radiation sensor as in claim 1, wherein said SEE sensor has an SEE coefficient of at least 10.

6. A beta radiation sensor as in claim 5, wherein said SEE sensor is a diamond-like carbon film having an SEE coefficient ranging from about 25 to about 50.

7. A beta radiation sensor as in claim 1, wherein said amplifier comprises an electron multiplier.

8. A beta radiation sensor as in claim 7, wherein said electron multiplier comprises one of a channel electron multiplier, a multi-channel plate, and a photomultiplier tube.

9. A beta radiation sensor which detects beta particles emitted by an object in the presence of background gamma particles, comprising:

a vacuum chamber adapted to contain said object and a sensor housing disposed so as to receive incident beta particles emitted by said object when said object is contained in said vacuum chamber;

a secondary electron emission (SEE) sensor disposed in said housing so as to detect said incident beta particles emitted by said object at the substantial exclusion of said gamma particles and to generate a first signal indicative of said incident beta particles; and

an amplifier which amplifies said first signal into a second signal indicative of the number of beta particles emitted by said object.

10. A beta radiation sensor as in claim 9, further comprising means responsive to said second signal for generating an audible signal representative of the number of beta particles emitted by said object.

11. A beta radiation sensor as in claim 9, further comprising means responsive to said second signal for generating a visual display representative of the number of beta particles emitted by said object.

12. A beta radiation sensor as in claim 9, wherein said SEE sensor has an SEE coefficient of at least 10.

13. A beta radiation sensor as in claim 12, wherein said SEE sensor is a diamond-like carbon film having an SEE coefficient ranging from about 25 to about 50.

14. A beta radiation sensor as in claim 9, wherein said amplifier comprises an electron multiplier.

15. A beta radiation sensor as in claim 14, wherein said electron multiplier comprises one of a channel electron multiplier, a multi-channel plate, and a photomultiplier tube.

16. A method of detecting beta particles emitted by an object in the presence of background gamma particles, comprising the steps of:

disposing a sealed housing enclosing a vacuum such that incident beta particles emitted by said object may pass into said sealed housing through an air-vacuum interface of said sealed housing that is substantially transparent to the passage of said incident beta particles so as to impinge upon a secondary electron emission (SEE) sensor disposed in said housing;

said SEE sensor detecting incident beta particles which have passed through said air-vacuum interface at the substantial exclusion of said gamma particles;

generating a first signal indicative of said incident beta particles on said SEE sensor; and

amplifying said first signal into a second signal indicative of the number of beta particles emitted by said object.

17. A method as in claim 16, further comprising the step of generating from said second signal an audible signal representative of the number of beta particles emitted by said object.

18. A method as in claim 16, further comprising the step of generating from said second signal a visual display representative of the number of beta particles emitted by said object.

19. A method of detecting beta particles emitted by an object in the presence of background gamma particles, comprising the steps of:

disposing said object in a vacuum chamber whereby beta particles emitted by said object may impinge upon a secondary electron emission (SEE) sensor disposed in said housing;

said SEE sensor detecting incident beta particles emitted by said object at the substantial exclusion of said gamma particles;

generating a first signal indicative of said incident beta particles on said SEE sensor; and

amplifying said first signal into a second signal indicative of the number of beta particles emitted by said object.

20. A method as in claim 19, further comprising the step of generating from said second signal an audible signal representative of the number of beta particles emitted by said object.

21. A method as in claim 19, further comprising the step of generating from said second signal a visual display representative of the number of beta particles emitted by said object.