Circulating fluid hypothermia method
First Claim
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1. A method for selective organ hypothermia, said method comprising:
- providing a circulating fluid apparatus having a chiller and a flexible coaxial catheter, said catheter having an insulated inner lumen and a hollow flexible heat transfer element adjacent its distal tip;
inserting said catheter through the vascular system of a patient to place said heat transfer element in a feeding artery of a selected organ;
supplying chilled perfluorocarbon fluid to said insulated inner lumen of said coaxial catheter;
cooling the interior of said heat transfer element with said chilled perfluorocarbon fluid;
cooling blood flowing in said feeding artery with said heat transfer element, to enable said cooled blood to flow distally into said selected organ and cool said organ; and
returning said perfluorocarbon fluid to said chiller.
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Abstract
A method for performing hypothermia of a selected organ without significant effect on surrounding organs or other tissues. A flexible coaxial catheter is inserted through the vascular system of a patient to place the distal tip of the catheter in an artery feeding the selected organ. A chilled perfluorocarbon fluid is pumped through an insulated inner supply conduit of the catheter to cool a flexible bellows shaped heat transfer element in the distal tip of the catheter. The heat transfer bellows cools the blood flowing through the artery, to cool the selected organ, distal to the tip of the catheter.
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Citations
8 Claims
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1. A method for selective organ hypothermia, said method comprising:
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providing a circulating fluid apparatus having a chiller and a flexible coaxial catheter, said catheter having an insulated inner lumen and a hollow flexible heat transfer element adjacent its distal tip; inserting said catheter through the vascular system of a patient to place said heat transfer element in a feeding artery of a selected organ; supplying chilled perfluorocarbon fluid to said insulated inner lumen of said coaxial catheter; cooling the interior of said heat transfer element with said chilled perfluorocarbon fluid; cooling blood flowing in said feeding artery with said heat transfer element, to enable said cooled blood to flow distally into said selected organ and cool said organ; and returning said perfluorocarbon fluid to said chiller.
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2. A method for selective organ hypothermia, said method comprising:
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providing a coaxial catheter, said catheter having an insulated inner lumen and a metallic heat transfer element; introducing said coaxial catheter into the vascular system of a patient to place said metallic heat transfer element in a feeding artery of an organ of the patient; cooling said metallic heat transfer element by circulating a refrigerant through said insulated inner lumen of said coaxial catheter; cooling blood in said feeding artery by contact with said cooled metallic heat transfer element; and cooling said organ by flow of said cooled blood through said feeding artery.
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3. A method for selective brain hypothermia, comprising:
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providing a flexible coaxial catheter, said flexible catheter having an insulated inner lumen and a flexible metallic heat transfer element; introducing said flexible coaxial catheter into the vascular system of a patient to place said flexible metallic heat transfer element in the carotid artery of the patient; cooling said flexible metallic heat transfer element by circulating a refrigerant through said insulated inner lumen of said flexible coaxial catheter; cooling blood in said carotid artery by contact with said cooled flexible metallic heat transfer element; and cooling the brain of the patient by flow of said cooled blood through said carotid artery.
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4. A method for selective hypothermia of the heart of a patient, comprising:
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providing a flexible coaxial catheter, said flexible coaxial catheter having an insulated inner lumen and a flexible metallic heat transfer element; introducing said flexible coaxial catheter into the vascular system of a patient to place said flexible metallic heat transfer element in a feeding artery of the heart of the patient; cooling said flexible metallic heat transfer element by circulating a refrigerant through said insulated inner lumen of said flexible coaxial catheter; cooling blood in said feeding artery by contact with said cooled flexible metallic heat transfer element; and cooling the heart of the patient by flow of said cooled blood through said feeding artery.
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5. A method for selective organ hypothermia, said method comprising:
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providing a circulating fluid apparatus having a chiller and a flexible coaxial catheter, said catheter having an inner lumen and a hollow flexible heat transfer element adjacent its distal tip; inserting said catheter through the vascular system of a patient to place said heat transfer element in a feeding artery of a selected organ; supplying chilled perfluorocarbon fluid to said inner lumen of said coaxial catheter; cooling the interior of said heat transfer element with said chilled perfluorocarbon fluid; cooling blood flowing in said feeding artery with said heat transfer element, to enable said cooled blood to flow distally into said selected organ and cool said organ; and returning said perfluorocarbon fluid to said chiller.
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6. A method for organ hypothermia, said method comprising:
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providing a coaxial catheter, said catheter having an inner lumen and a metallic heat transfer element; introducing said coaxial catheter into the vascular system of a patient to place said metallic heat transfer element in an artery of an organ of the patient; cooling said metallic heat transfer element by circulating a refrigerant through said inner lumen of said coaxial catheter; cooling blood in said artery by contact with said cooled metallic heat transfer element; and cooling said organ by flow of said cooled blood through said artery.
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7. A method for selective brain hypothermia, comprising:
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providing a flexible coaxial catheter, said flexible catheter having an inner lumen and a flexible heat transfer element; introducing said flexible coaxial catheter into the vascular system of a patient to place said flexible heat transfer element in the carotid artery of the patient; cooling said flexible heat transfer element by circulating a refrigerant through said inner lumen of said flexible coaxial catheter; cooling blood in said carotid artery by contact with said cooled flexible heat transfer element; and cooling the brain of the patient by flow of said cooled blood through said carotid artery.
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8. A method for selective hypothermia of the heart of a patient, comprising:
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providing a flexible coaxial catheter, said flexible coaxial catheter having an inner lumen and a flexible heat transfer element; introducing said flexible coaxial catheter into the vascular system of a patient to place said flexible heat transfer element in a feeding artery of the heart of the patient; cooling said flexible heat transfer element by circulating a refrigerant through said inner lumen of said flexible coaxial catheter; cooling blood in said feeding artery by contact with said cooled flexible heat transfer element; and cooling the heart of the patient by flow of said cooled blood through said feeding artery.
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Specification