Transmyocardial revascularization using radiofrequency energy

• US 6,156,031 A
• Filed: 06/29/1998
• Issued: 12/05/2000
• Est. Priority Date: 08/09/1995
• Status: Expired due to Term

• Current Assignee: Cryolife Incorporated
• Original Assignee: Eclipse Surgical Technologies, Inc. (Cryolife Incorporated)
• Inventors: Simpson, Carl J., Kesten, Randy J., Aita, Michael
• Primary Examiner(s): Dvorak, Linda C. M.
• Assistant Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US09/107,077
• Time in Patent Office: 890 Days
• Field of Search: 606/33, 606/34, 606/37, 606/38, 606/41, 606/122, 604/114
• US Class Current: 606/33
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00392 Transmyocardial revascularisation
• CPC Class Codes: A61B 2018/00738 Depth, e.g. depth of ablation
• CPC Class Codes: A61B 2018/00839 Bioelectrical parameters, e.g. ECG, EEG

Abstract

The invention is directed to a system and method for revascularization of a patient'"'"'s heart tissue by at least one burst of RF energy over an interval of about 1 to about 500 msec, preferably about 30 to about 130 msec. The device preferably has an elongated insulated, electrical conducting shaft with an uninsulated distal tip which is configured to emit RF energy. A method is described for myocardial revascularization of a human heart in which an elongated flexible device is used which includes a radiofrequency ablation device. In some embodiments, the device is configured to be introduced percutaneously, on other embodiments, the device is configured to be introduced intraoperatively. The RF energy emitter is advanced to a position adjacent a desired area of the heart wall. The device is activated, moving tissue to form a revascularization channel.

Claims

1. A method of forming a revascularization channel in a desired region of a wall of a patient'"'"'s heart, comprising:

a) providing an elongated shaft having proximal and distal ends and an RF energy emitter located at the distal end;

b) introducing the elongated shaft into the body of the patient and directing the RF energy emitter to the desired region of the heart wall wherein the revascularization channel is to be formed; and

c) supplying RF energy to the RF energy emitter to form a revascularization channel in a myocardial layer of the patient'"'"'s heart wall.

2. The method of claim 1 wherein the elongated shaft is a flexible intravascular shaft, further comprising the steps of:

a) introducing the shaft into the patient'"'"'s body by advancing the shaft through the patient'"'"'s vasculature until a distal portion thereof is disposed within a chamber of the patient'"'"'s heart defined by the wall;

b) directing the RF energy emitter to the endocardial layer of the desired region of the wall; and

c) supplying RF energy to the RF energy emitter to first remove tissue from an endocardial layer of the patient'"'"'s heart wall when forming the revascularization channel.

3. The method of claim 1 wherein the elongated shaft is configured to be introduced through the patient'"'"'s chest wall, further comprising the steps of:

a) directing the RF energy emitter to the epicardial layer of the desired region of the wall; and

b) supplying RF energy to the RF energy emitter to remove tissue sequentially from the epicardial layer, a myocardial layer and an endocardial layer to form the revascularization channel.

4. The method of claim 2 wherein the RF energy emitter is advanced through the endocardial layer at a first energy level and within the myocardial layer at a second energy level lower than the first energy level.

5. The method of claim 1 wherein the elongated shaft includes means for perfusing and aspirating the desired region of the heart wall, further comprising aspirating the removed tissue from the patient'"'"'s heart.

6. The method of claim 1 wherein the RF energy emitter comprises a probe connected to a first and second electrode which extend the length of the elongated shaft, further comprising the step of supplying RF energy across the electrodes to form the revascularization channel.

7. The method of claim 6 wherein the revascularization channel is formed by supplying RF energy between about 30 MHZ to about 10 GHz across the electrodes.

8. A method of forming a revascularization channel in a desired region of a wall of a patient'"'"'s heart, the wall having an inner endocardium layer, an outer epicardium layer and an intermediate myocardium layer between the endocardium and the epicardium layers, comprising:

a) providing an elongated device having proximal and distal ends and a means to form a revascularization channel comprising radiofrequency ablation means located at the distal end;

b) introducing the device into the body of the patient and directing the distal end of the device to the desired region of the wall wherein the revascularization channel is to be formed; and

c) supplying radiofrequency energy to the radiofrequency ablation means to form a revascularization channel in the myocardium layer.