Centrifugal filtration apparatus
First Claim
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1. A centrifugal liquid filtration apparatus for separating filtrate and concentrate from a solution capable of being used in a fixed angle or swinging bucket centrifuge rotor comprising:
- (a) a concentrate tube assembly capable of containing a solution therein, comprising;
(i) a concentrate tube,(ii) a micro-porous filter element,(iii) a filter cover,(iv) a concentrate tube cap, and(v) a filtrate tube for collecting filtrate;
(b) said concentrate tube assembly containing a first chamber capable of containing unfiltered liquid therein, said first chamber being divided into an upper part and a lower part;
(c) a second chamber capable of collecting filtered liquid therein, said second chamber being in fluid flow relationship with the lower part of the first chamber;
(d) a means for filtering liquid within the first chamber prior to flowing into the second chamber; and
(e) a port leading from the second chamber into the interior of said filtrate tube, said port being disposed a sufficient distance above the bottom of the second chamber whereby the lower part of said first chamber is prevented from filtering to dryness.
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Abstract
A filtration device for separating filtrate and concentrate from a solution that contains a dead stop feature. The dead stop volume is determined by the location of an outlet port. The apparatus includes a housing with a means for collecting filtrate and a filter unit insertable within the housing. The filter unit contains a semipermeable membrane thereon for separating filtrate from concentrate.
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Citations
63 Claims
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1. A centrifugal liquid filtration apparatus for separating filtrate and concentrate from a solution capable of being used in a fixed angle or swinging bucket centrifuge rotor comprising:
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(a) a concentrate tube assembly capable of containing a solution therein, comprising; (i) a concentrate tube, (ii) a micro-porous filter element, (iii) a filter cover, (iv) a concentrate tube cap, and (v) a filtrate tube for collecting filtrate; (b) said concentrate tube assembly containing a first chamber capable of containing unfiltered liquid therein, said first chamber being divided into an upper part and a lower part; (c) a second chamber capable of collecting filtered liquid therein, said second chamber being in fluid flow relationship with the lower part of the first chamber; (d) a means for filtering liquid within the first chamber prior to flowing into the second chamber; and (e) a port leading from the second chamber into the interior of said filtrate tube, said port being disposed a sufficient distance above the bottom of the second chamber whereby the lower part of said first chamber is prevented from filtering to dryness. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A centrifugal liquid filtration apparatus for separating filtrate and concentrate from a solution capable of being used in a fixed angle or swinging bucket centrifuge rotor comprising:
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(a) a concentrate tube assembly capable of containing a solution therein, comprising; (i) a concentrate tube, (ii) a micro-porous filter element, and (iii) a filter cover, (b) a filtrate tube for collecting filtrate; (c) a filtrate tube cap; (d) a filtrate tube cap gasket; (e) said concentrate tube assembly containing a first chamber capable of containing unfiltered liquid therein, said first chamber being divided into an upper part and a lower part; (f) a second chamber capable of collecting filtered liquid therein, said second chamber being in fluid flow relationship with the lower part of the first chamber; (g) a means for filtering liquid within the first chamber prior to flowing into the second chamber; and (h) a port leading from the second chamber into the interior of said filtrate tube, said port being disposed a sufficient distance above the bottom of the second chamber whereby the lower part of said first chamber is prevented from filtering to dryness. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28)
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29. A centrifugal liquid filtration apparatus for separating filtrate and concentrate from a solution capable of being used in a fixed angle or swinging bucket centrifuge rotor comprising:
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(a) a concentrate tube assembly capable of containing a solution therein, comprising; (i) a concentrate tube, (ii) two micro-porous filter elements, and (iii) two filter covers, (b) said concentrate tube assembly containing a first chamber capable of containing unfiltered liquid therein, said first chamber being divided into an upper part and a lower part; (c) a second chamber capable of collecting filtered liquid therein, said second chamber being in fluid flow relationship with the lower part of the first chamber; (d) a third chamber capable of collecting filtered liquid therein, said third chamber being in fluid flow relationship with the lower part of the first chamber; (e) a means for filtering liquid within the first chamber prior to flowing into the second and third chambers; and (f) a first port leading from the second chamber into the interior of said filtrate tube; (g) a second port leading from the third chamber into the interior of said filtrate tube said first and second ports being disposed a sufficient distance above the bottom of the second chamber and the third chambers respectively whereby the lower part of said first chamber is prevented from filtering to dryness. - View Dependent Claims (30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40)
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41. A centrifugal liquid filtration apparatus for separating filtrate and concentrate from a solution capable of being used in a fixed angle or swinging bucket centrifuge rotor comprising:
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(a) a concentrate tube assembly capable of containing a solution therein, comprising; (i) a concentrate tube, (ii) a micro-porous filter element, (iii) a filter cover, and (iv) a filter sealing gasket (b) a filtrate tube for collecting filtrate; (c) a filtrate tube cap; (d) a filtrate tube cap gasket; (e) said concentrate tube assembly containing a first chamber capable of containing unfiltered liquid therein, said first chamber being divided into an upper part, a central part, and a lower part; (f) said upper part and said lower part being connected by said central part; (h) said lower part comprising; (i) a vent chamber; (ii) a pipette access chamber; (iii) at least one vent channel; (iv) a dead stop chamber; and (v) a thin channel member; (h) a second chamber capable of collecting filtered liquid therein, said second chamber being in fluid flow relationship with the lower part of the first chamber; (i) a means for filtering liquid within the first chamber prior to flowing into the second chamber; and (j) a port leading from the second chamber into the interior of said filtrate tube, said port being disposed a sufficient distance above the bottom of the second chamber whereby the lower part of said first chamber is prevented from filtering to dryness. - View Dependent Claims (42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63)
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Specification