Sustained release ophthalmic compositions containing water soluble medicaments
DC CAFCFirst Claim
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1. An ophthalmic composition comprising:
- a pharmacologically effective amount of a water soluble ophthalmic medicament, about 0.5 to 2.0% crosslinked carboxy-containing polymer, about 0.5 to 5.0% sugar, and water;
said composition having a pH of at least about 6.7 and a viscosity of from about 1000 to 5000 cps.
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Abstract
An ophthalmic composition that provides sustained release of a water soluble medicament is formed comprising a crosslinked carboxy-containing polymer, a medicament, a sugar and water. The composition has a pH of at least 6.7 but a viscosity of from about 1000 to 5000 cps.
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26 Claims
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1. An ophthalmic composition comprising:
a pharmacologically effective amount of a water soluble ophthalmic medicament, about 0.5 to 2.0% crosslinked carboxy-containing polymer, about 0.5 to 5.0% sugar, and water;
said composition having a pH of at least about 6.7 and a viscosity of from about 1000 to 5000 cps.- View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22)
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23. An ophthalmic composition comprising:
(a) water, (b) a polymer component that consists essentially of one or more crosslinked carboxy-containing polymers, (c) sugar, and (c) timolol;
wherein said composition has a pH of at least 7.0 and a viscosity of from about 1500 to 3500 cps.- View Dependent Claims (24, 25, 26)
Specification