Analytical test element with a blister filled with liquid

• US 6,159,747 A
• Filed: 02/23/1998
• Issued: 12/12/2000
• Est. Priority Date: 03/06/1997
• Status: Expired due to Fees

• Current Assignee: Roche Diagnostics GmbH (Roche Holding AG)
• Original Assignee: Roche Diagnostics GmbH (Roche Holding AG)
• Inventors: Harttig, Herbert, Klein, Christian
• Primary Examiner(s): Chin, Christopher L.
• Application Number:
  US09/027,894
• Time in Patent Office: 1,023 Days
• Field of Search: 422/56, 422/58, 422/61, 435/287.1, 435/287.2, 435/287.6, 435/287.7, 435/287.8, 435/287.9, 435/970, 435/805, 435/810, 436/169, 436/514, 436/518, 436/530, 436/810
• US Class Current: 436/518
• CPC Class Codes: G01N 33/521 Single-layer analytical elements
• CPC Class Codes: G01N 33/54366 Apparatus specially adapted for solid-phase testing
• CPC Class Codes: Y10S 435/805 Test papers
• CPC Class Codes: Y10S 435/81 Packaged device or kit
• CPC Class Codes: Y10S 435/97 Test strip or test slide
• CPC Class Codes: Y10S 436/81 Tube, bottle, or dipstick

Abstract

The invention concerns an analytical test element containing an absorbent material with a sample application and detection zone and a blister filled with liquid on a support, wherein the support has a notch within the support surface such that a spike forms there when the support is bent with which the blister can be opened so that liquid escapes and comes into contact with the absorbent material as well as a process for the production of such an analytical test element and a method for determining an analyte by means of such an analytical test element.

Claims

1. An analytical test element comprising absorbent material with a sample application zone and detection zone, both zones being arranged on the same absorbent material or on different absorbent materials, and a blister filled with liquid on a support, wherein the support has a notch within the support surface such that a spike forms there when the support is bent which enables the blister to be opened so that liquid escapes and contacts with the absorbent material.

2. The analytical test element as claimed in claim 1, wherein the blister is in contact with the absorbent material.

3. The analytical test element of claim 1, wherein said sample application and said detection zone are identical with regard to the absorbent material.

4. The analytical test element of claim 1, wherein said sample application zone and said detection zone are separate regions.

5. The analytical test element of claim 1, wherein said sample application zone and said detection zone are composed of different materials.

6. The analytical test element of claim 1, wherein said notch within the support surface is V-shaped.

7. The analytical test element of claim 1, wherein said blister is mounted on said absorbent material.

8. The analytical test element of claim 1, wherein said blister is directly attached to said support.

9. The analytical test element of claim 1, wherein said blister is held on said support by means of a foil which stretches over said blister and is directly attached to said support in front of and behind said blister.

10. The analytical test element of claim 1, wherein the analytical element is located in a housing in such a way that said support can be bent so that a spike forms with which said blister can be opened and that said blister is covered by said housing to such an extent that said blister cannot avoid said spike when said support is bent.

11. The analytical test element of claim 1, wherein the absorbent material outside of said sample application zone and said detection zone is covered in such a way by a liquid-impermeable foil that it is located between said foil and said support.

12. The analytical test element of the claim 2, wherein said sample application and said detection zone are identical with regard to the absorbent material.

13. The analytical test element of the claim 2, wherein said sample application zone and said detection zone are separate regions.