Compounds and therapy for resisting memory loss in humans

• US 6,159,986 A
• Filed: 11/02/1999
• Issued: 12/12/2000
• Est. Priority Date: 11/02/1999
• Status: Expired due to Fees

• Current Assignee: Altman, David A.
• Original Assignee: Altman, David A.
• Inventors: Altman, David A.
• Primary Examiner(s): Lilling, Herbert J.
• Application Number:
  US09/431,868
• Time in Patent Office: 406 Days
• Field of Search: 424/195.1, 514/295, 514/732, 514/738, 514/249, 514/261, 546/93, 546/97
• US Class Current: 514/295
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 31/12 Ketones
• CPC Class Codes: A61K 31/47 Quinolines; Isoquinolines

Abstract

Therapies and compounds for the inhibition of memory loss. In one embodiment, a combination of Huperzine A and hypericin is employed.

Claims

1. A process for the inhibition of memory impairment in a mammal, comprising the steps of administering to a mammal an effective amount of about 0.1 to about 2 parts by weight of a total dose of Huperzine A and about 1.5 to about 6 parts by weight of a total dose of hypericin.

2. A process according to claim 1 wherein said Huperzine A is present in an amount up to about 0.2 parts by weight and said hypericin is present in an amount of about 2.7 parts by weight.

3. A process according to claim 1 further comprising compounding said combination into a single admixture prior to said administering step.

19. A process according to claim 1, wherein about 0.1 milligrams to about 2 milligrams Huperzine A and about 0.7 to about 2.8 milligrams hypericin are administered to a mammal per day per 70 kilograms of body weight of said mammal.

4. A compound for inhibiting memory loss, comprising an effective amount of a combination of about 0.1 to about 2 parts by weight of the compound of hypericin A and about 1.5 to about 6 parts by weight of the compound of hypericin.

5. A compound according to claim 4 wherein said Huperzine A is present in an amount of about 0.2 parts by weight of the compound and said hypericin is present in an amount of about 2.7 parts by weight of the compound.

6. A compound according to claim 4, wherein said compound is a solid.

7. A compound according to claim 4, wherein said compound is in a liquid.

8. A compound according to claim 4, further comprising an anti-oxidant.

9. A compound according to claim 4, further comprising Vitamin B.

10. A compound according to claim 4, further comprising Vitamin D.

11. A compound according to claim 4, further comprising Vitamin K.

12. A compound according to claim 4, further comprising gingko.

13. A compound according to claim 4, further comprising ginseng.

14. A compound according to claim 4, further comprising Echinacea.

15. A compound according to claim 4, further comprising amino acids.

16. A compound according to claim 4, further comprising folic acid.

17. A compound according to claim 4, further comprising creatine.

18. A compound according to claim 4, further comprising fiber supplement.