Channel-specific control of pulse integration in a gamma camera system in response to pulse pile-up

• US 6,160,259 A
• Filed: 10/23/1998
• Issued: 12/12/2000
• Est. Priority Date: 10/23/1998
• Status: Expired due to Term

• Current Assignee: Koninklijke Philips Electronics N.V. (Koninklijke Philips N.V.)
• Original Assignee: Adam Laboratories Inc.
• Inventors: Petrillo, Michael J., Wellnitz, Donald R., Scharf, Thomas E.
• Primary Examiner(s): Hannaher, Constantine
• Assistant Examiner(s): Gabor, Otilia
• Application Number:
  US09/178,352
• Time in Patent Office: 781 Days
• Field of Search: 250/363.07, 250/363.02, 250/363.03, 250/369, 250/395
• US Class Current: 250/363.07
• CPC Class Codes: G01T 1/171 Compensation of dead-time counting losses see provisionally also G01T1/17

Abstract

A method and apparatus for selectively integrating PMT channel signals in a gamma camera system are described. A trigger word is decoded to determine which of multiple PMT channels are affected by a given scintillation event. When two scintillation events overlap both spatially and temporally, only those channels which are affected by both events stop integrating in response to the second event. Pre-pulse pile-up is corrected by removing the tail of a preceding pulse from a current pulse using an approximation of the tail of the preceding pulse based upon the instantaneous energy of the current pulse and the current countrate. Extrapolation of the tail of the current pulse may also be performed in essentially the same manner.

Claims

1. A method of detecting radiation induced events in a radiation detector, the radiation detector including a plurality of channels, the method comprising:

in response to a first event which affects both a first channel and a second channel of the plurality of channels, integrating data of the first channel and integrating data of the second channel; and

in response to a second event which temporally overlaps the first event and which affects the second channel but not the first channel, stopping said integrating of the data of the second channel and continuing said integrating of the data of the first channel.

2. A method according to claim 1, further comprising correcting the data of the second channel for pulse pile-up associated with the first and second events without correcting the data of the first channel for said pile-up.

3. A method according to claim 2, wherein said correcting comprises estimating a pulse tail for the first event for the second channel.

4. A method of correcting for pulse pile-up in a nuclear medicine imaging system, the imaging system including a detector, the detector including a plurality of photomultiplier tubes (PMTs), the method comprising:

in response to a first scintillation event affecting both a first PMT and a second PMT of the plurality of PMTs, integrating an output of the first PMT and integrating an output of the second PMT;

in response to a second scintillation event which affects the second PMT but not the first PMT and which overlaps the first scintillation event temporally;

determining that the second scintillation event affects the second PMT and not the first PMT;

stopping said integrating of the output of the second PMT; and

continuing said integrating of the output of the first PMT.

5. A method according to claim 4, further comprising correcting an output of the second PMT for pile-up associated with the first and second scintillation events without correcting the output of the first PMT for said pile-up.

6. A method of correcting for pulse pile-up associated with a gamma camera, the gamma camera including a plurality of light detectors for detecting scintillation events, the method comprising:

integrating an output of each of the light detectors that is affected by a first scintillation event;

determining which of the plurality of light detectors are affected by both the first and a second scintillation event, the second scintillation event overlapping the first scintillation event temporally and spatially;

stopping said integrating for each of the light detectors that is affected by both the first and second scintillation events; and

continuing said integrating for each of the light detectors that is affected by the first scintillation event but not the second scintillation event.

7. A method according to claim 6, further comprising correcting the outputs of the light detectors that are affected by both the first and second scintillation events for pile-up associated with the first and second scintillation events.

8. A method of correcting for pulse pile-up in a nuclear medicine imaging system, the imaging system including a detector, the detector including a plurality of photomultiplier tubes (PMTs), the method comprising:

detecting a first scintillation event;

integrating an output of each of the PMTs affected by the first scintillation event;

detecting a second scintillation event, the second scintillation event overlapping the first scintillation event temporally and spatially;

determining which of the plurality of PMTs are affected by both the first and the second scintillation events;

stopping said integrating for each of the PMTs affected by both the first and second scintillation events; and

continuing said integrating for each of the PMTs affected by the first scintillation event but not the second scintillation event.

9. A method according to claim 8, further comprising correcting the outputs of only the PMTs affected by both the first and second scintillation events for pile-up associated with the first and second scintillation events.

10. A method of correcting for pulse pile-up in a nuclear medicine imaging system, the nuclear medicine imaging system including a gamma ray detector, the gamma ray detector including a plurality of photomultiplier tubes (PMTs), the method comprising:

detecting a first scintillation event;

integrating an output of each of the PMTs affected by the first scintillation event;

detecting a second scintillation event, the second scintillation event overlapping the first scintillation event temporally and spatially;

determining which of the plurality of PMTs are affected by both the first and the second scintillation events;

stopping said integrating for each of the PMTs affected by both the first and second scintillation events; and

continuing said integrating for each of the PMTs affected by the first scintillation event but not the second scintillation event;

correcting a channel signal for each of the PMTs affected by both the first and second scintillation events for pulse pile-up associated with the first and second events without correcting channel signals for the PMTs not affected by the second event for said pile-up associated with the first and second events.

11. A method according to claim 10, wherein said correcting comprises estimating a pulse tail for the first event for each of the PMTs affected by both the first and second scintillation events.

12. An imaging system comprising:

a support structure;

a processing system; and

a radiation detector coupled to the processing system and supported by the support structure, the radiation detector including a plurality of channels, the radiation detector configured to respond to a first event which affects both a first channel and a second channel of the plurality of channels by integrating an output of the first channel and integrating an output of the second channel, the radiation detector further configured to respond to a second event which temporally overlaps the first event and which affects the second channel but not the first channel by stopping said integrating of the output of the second channel and continuing said integrating of the output of the first channel.

13. An imaging system according to claim 12, wherein the radiation detector is further configured to estimate a pulse tail for the first event for the second channel and not the first channel.

14. A nuclear medicine imaging system comprising:

means for detecting a plurality of scintillation events including a first scintillation event and a second scintillation event, the second scintillation event overlapping the first scintillation event temporally and spatially, the means for detecting including a plurality of channels;

means for integrating an output of each of the channels affected by the first scintillation event;

means for stopping said integrating for each of the channels affected by both the first and second scintillation events;

means for continuing said integrating for each of the channels affected by the first scintillation event but not the second scintillation event;

means for receiving data representing integrated outputs of each of the channels; and

means for generating images of an object based on the data.

15. A nuclear medicine imaging system according to claim 14, further comprising means for correcting the outputs of only the PMTs affected by both the first and second scintillation events for pile-up associated with the first and second scintillation events.

16. A nuclear medicine imaging system according to claim 15, wherein the means for correcting comprises means for estimating a pulse tail of the first event for each of the PMTs affected by both the first event and the second event.

17. A gamma camera system comprising:

a gantry;

a pair of gamma ray detectors movably supported by the gantry, each of the gamma ray detectors including;

a scintillator;

a plurality of light detectors optically coupled to the scintillator;

timing circuitry configured to generate trigger signals in response to outputs of the light detectors;

integration circuitry configured to integrate outputs of the light detectors in response to the trigger signals, the integration circuitry further configured to integrate the output of each of the light detectors affected by a first scintillation event and to integrate the output of each of the light detectors affected by a second scintillation event, the second scintillation event overlapping the first scintillation event temporally and spatially, the integration circuitry further configured to respond to the second scintillation event by stopping integration for each of the light detectors affected by both the first and second scintillation events and continuing integration for each of the light detectors affected by the first scintillation event but not the second scintillation event;

positioning circuitry configured to generate position data based on integrated outputs of the light detectors; and

a processing system coupled to each of the detectors and configured to generate images of an object based on the position data.

18. A gamma camera system according to claim 17, further comprising correction circuitry configured to correct the outputs of only the light detectors affected by both the first and second scintillation events for pile-up associated with the first and second scintillation events, in response to the second event.

19. A gamma camera system according to claim 18, wherein the correction circuitry comprises circuitry configured to estimate a pulse tail of the first event for each of the PMTs affected by both the first event and the second event.