Blood processing chamber counter-balanced with blood-free liquid

• US 6,168,561 B1
• Filed: 08/19/1999
• Issued: 01/02/2001
• Est. Priority Date: 07/01/1997
• Status: Expired due to Fees

• Current Assignee: Baxter International Inc.
• Original Assignee: Baxter International Inc.
• Inventors: Cantu, Robert J, Min, Kyungyoon, Reitz, Douglas W
• Primary Examiner(s): KIM, SUN U
• Application Number:
  US09/377,339
• Time in Patent Office: 502 Days
• Field of Search: 210/718, 210/739, 210/767, 210/782, 210/787, 210/97, 210/143, 210/218, 210/416.1, 494/23, 494/22, 494/27, 494/43, 494/45, 494/37
• US Class Current: 494/37
• CPC Class Codes: A61M 1/362227 the interface providing means for actuating on functional elements of the cassette, e.g. plungers
• CPC Class Codes: A61M 1/36225 with blood pumping means or components thereof
• CPC Class Codes: A61M 1/362261 at least one cassette surface or portion thereof being flexible, e.g. the cassette having a rigid base portion with preformed channels and being covered with a foil
• CPC Class Codes: A61M 1/362265 Details of valves
• CPC Class Codes: A61M 1/362266 Means for adding solutions or substances to the blood
• CPC Class Codes: A61M 1/3693 using separation based on different densities of components, e.g. centrifuging
• CPC Class Codes: A61M 1/3696 with means for adding or withdrawing liquid substances during the centrifugation, e.g. continuous centrifugation
• CPC Class Codes: B01D 21/262 by using a centrifuge
• CPC Class Codes: B01D 21/32 Density control of clear liquid or sediment, e.g. optical control ; Control of physical properties
• CPC Class Codes: B01D 21/34 Controlling the feed distribution; Controlling the liquid level ; Control of process parameters
• CPC Class Codes: B01D 2221/10 Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues
• CPC Class Codes: B04B 2005/045 having annular separation channels
• CPC Class Codes: B04B 2009/143 by weight compensation with liquids
• CPC Class Codes: B04B 9/14 Balancing rotary bowls balancing per se G01M; Schrappers

Abstract

Blood processing systems and methods rotate a processing chamber on a rotating element. The processing chamber includes a first compartment and a second compartment. Blood is conveyed into the first compartment for centrifugal separation into components. A liquid free of blood occupies the second compartment to counter-balance the first compartment during rotation on the rotating element. In one embodiment, the second compartment is served by a single fluid flow access. Prior to use, the single access is coupled to tubing, through which a vacuum is drawn to remove air from the second compartment. While the vacuum exists, communication is opened between the tubing and a source of liquid. The vacuum draws the liquid into the second compartment through the single access, thereby priming the second compartment for use.

Claims

1. A blood processing system comprising

a rotating element operated to rotate about an axis, and

a processing chamber that extends circumferentially about the axis on the rotating element for common rotation with the rotating element, the processing chamber including a first compartment containing blood for centrifugal separation into components, the processing chamber also including a second compartment circumferentially spaced from the first compartment about the axis and containing a liquid free of blood which circumferentially counter-balances the first compartment during rotation on the rotating element.

3. A system according to claim 1 or 2

wherein the second compartment includes a single fluid flow access.

4. A system according to claim 1 or 2

wherein the second compartment is substantially free of air.

5. A system according to claim 1 or 2

wherein the liquid in the second compartment is subject to a positive pressure.

2. A blood processing system comprising

a rotating element having a circumference and operated to rotate about an axis, and

a processing chamber that extends circumferentially about the axis on the rotating element for common rotation with the rotating element, the processing chamber including a first compartment containing blood for centrifugal separation into components, the first compartment occupying less than the entire circumference of the rotating element, the processing chamber also including a second compartment circumferentially spaced from the first compartment about the axis and containing a liquid free of blood which circumferentially counter-balances the first compartment during rotation on the rotating element.

6. A blood processing system comprising

a rotating element,

a processing chamber made to be secured to the rotating element for common rotation with the rotating element the processing chamber including a first compartment having an inlet port for conveying blood into the first compartment for centrifugal separation into components and an outlet port for conveying a separated component from the first compartment, the processing chamber also including a second compartment including a single fluid flow access for conveying liquid into the second compartment to counter-balance the first compartment during rotation on the rotating element,

tubing communicating with the single access,

a pump element in the tubing, and

a controller coupled to the pump element operative in a first mode to operate the pump element to draw a vacuum in second compartment, the pump element being operative in a second mode to opening communication between the tubing and a source of liquid while the vacuum exists in the second compartment, whereby the vacuum draws liquid into the second compartment to prime the second compartment and counter-balance the first compartment.

7. A blood processing system according to claim 6

wherein, during the second mode, the controller commands the pump element to convey the liquid into the second compartment while the vacuum also draws the liquid into the second compartment to impart a positive pressure condition in the second compartment.

8. A blood processing method comprising the steps of

rotating a processing chamber on a rotating element about an axis, the processing chamber including a first compartment and a second compartment circumferentially spaced from the first compartment,

conveying blood into the first compartment for centrifugal separation into components, and

filling the second compartment with a liquid free of blood to circumferentially counter-balance the first compartment during rotation on the rotating element.