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Method and kit for detecting Helicobacter pylori

  • US 6,171,811 B1
  • Filed: 07/20/1999
  • Issued: 01/09/2001
  • Est. Priority Date: 11/12/1996
  • Status: Expired due to Term
First Claim
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1. A method for the detection of Helicobacter pylori, based on the carbon-13 labelled urea breath test, which comprises the stages of:

  • a) administering to the patient an aqueous solution of citric acid which comprises citric acid in an amount sufficient to yield a pH comprised between 2 and 2.5;

    b) collecting a sample of the patient'"'"'s breath with the object of determining the baseline content of carbon-13;

    c) administering to the patient a suitable amount of carbon-13 labelled urea;

    d) collecting a sample of the patient'"'"'s breath with the object of determining the content of carbon-13 after the administration of the carbon-13 labelled urea; and

    e) analysing the breath sample collected to determine the carbon-13 content before and after the administration of carbon-13 labelled urea.

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