Production of enantiomer-free biarylketocarboxylic acids
First Claim
Patent Images
1. Process for the preparation of enantiomerically pure biarylketocarboxylic acids, characterized in that the auxiliary base used in the resolution is S-phenylethyl-amine.
1 Assignment
0 Petitions
Accused Products
Abstract
The invention relates to a continuous process for the preparation of enantiomerically pure biarylketocarboxylic acids, S-phenylethylamine being employed as an auxiliary base in the resolution. Biarylketocarboxylic acids, in particular substituted biaryl-4-ketocarboxylic acids, are inhibitors of enzymes of the matrix metalloproteinases class. By inhibition of the abovementioned enzymes, it is possible, for example, to control osteoarthritis, rheumatoid arthritis and metastases.
-
Citations
1 Claim
-
1. Process for the preparation of enantiomerically pure biarylketocarboxylic acids, characterized in that the auxiliary base used in the resolution is S-phenylethyl-amine.
Specification
-
- Resources
Litigation Campaign Assessment
Thank you for your request. You will receive a custom alert email when the Litigation Campaign Assessment is available.
×
-
Current AssigneeBayer AG
-
Original AssigneeBayer AG
-
InventorsPreiss, Michael
-
Primary Examiner(s)Killos, Paul J.
-
Application NumberUS09/381,597Time in Patent Office477 DaysField of Search562/401, 562/428US Class Current562/401CPC Class CodesC07B 57/00 Separation of optically-act...C07C 319/28 Separation; PurificationC07C 323/56 the carbon skeleton contain...
