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Measurement of glycated hemoglobin

  • US 6,174,734 B1
  • Filed: 10/24/1997
  • Issued: 01/16/2001
  • Est. Priority Date: 10/24/1997
  • Status: Expired due to Term
First Claim
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1. A method for assaying GHb in a biological fluid, if present, comprising the steps of:

  • a. providing a solid support member, which member comprises a predetermined amount of a Hp, b. contacting said biological fluid with said support member, thereby forming a GHb/Hb-saturated support member, c. contacting said GHb/Hb-saturated support member with a Hb/Hp-specific probe under conditions that allow binding of said Hb/Hp-specific probe to its target, said target consisting of Hb, d. removing unbound Hb/Hp-specific probe, and e. determining the amount of said HblHp-specific probe bound to captured Hb, and calculating how much GHb is in said biological fluid, if present.

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