Emboli filtration system and methods of use

• US 6,179,859 B1
• Filed: 07/16/1999
• Issued: 01/30/2001
• Est. Priority Date: 07/16/1999
• Status: Expired due to Term

• Current Assignee: Boston Scientific Scimed (Boston Scientific Corporation)
• Original Assignee: Baff LLC
• Inventors: Horzewski, Michael, Bates, Mark C.
• Primary Examiner(s): Hirsch, Paul J.
• Application Number:
  US09/354,897
• Time in Patent Office: 564 Days
• Field of Search: 606/200, 606/127, 606/114
• US Class Current: 606/200
• CPC Class Codes: A61F 2/0108 Both ends closed, i.e. legs gathered at both ends
• CPC Class Codes: A61F 2002/015 Stop means therefor
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61M 2025/09183 having tools at the distal tip

Abstract

An emboli filtration apparatus is provided comprising a guide wire having a filter element captured thereon, so that the guide wire is free to rotate and translate while the filter element remains stationary. The apparatus allows for movement and rotation of the guide wire as devices are advanced over it to treat occlusive disease, substantially without dislodging the filter element.

Claims

1. Apparatus for filtering emboli from blood flowing through a vessel, the apparatus comprising:

a guide wire having a distal region and a stop on the distal region;

a capture ring disposed for translation on the guide wire, the stop limiting translation of the capture ring in a distal direction; and

a filter sac connected to the capture ring.

2. The apparatus of claim 1 wherein, when the filter sac is deployed in the vessel, rotation or distal translation of the guide wire relative to the capture ring does not displace the filter sac, but retraction of the guide wire in a proximal direction causes the stop to abut against the capture ring.

3. The apparatus of claim 1 further comprising a plurality of self-expanding struts coupled between the filter sac and the capture ring.

4. The apparatus of claim 1 further comprising an elastomeric cone affixed to a distal portion of the filter sac.

5. The apparatus of claim 3 further comprising a cylindrical sleeve coupled between the plurality of self-expanding struts and the filter sac.

6. Apparatus for filtering emboli from blood flowing through a vessel, the apparatus comprising:

a guide wire having a first portion having a first diameter and a distal region having a second diameter greater than the first diameter; and

a filter element having a capture ring disposed for translation on the first portion, the capture ring having an aperture greater than the first diameter but smaller than the second diameter,

wherein rotation or distal translation of the guide wire relative to the capture ring does not displace the filter element.

7. The apparatus of claim 6 wherein the filter element comprises an expandable sac.

8. The apparatus of claim 7 wherein the filter element further comprises a plurality of struts coupling the expandable sac to the capture ring.

9. The apparatus of claim 8 wherein the struts are self-expanding.

10. The apparatus of claim 7 wherein the filter element further comprises an elastomeric cone affixed to a distal portion of the expandable sac.

11. The apparatus of claim 6 wherein the guide wire further comprises a flange disposed on the distal region having a diameter larger than the diameter of the aperture in the capture ring.

12. The apparatus of claim 8 wherein the filter element further comprises a cylindrical sleeve coupled between the plurality of struts and the expandable sac.

13. The apparatus of claim 7 wherein the filter element further comprises a distal ring coupled to the expandable sac, the distal ring having a bore with a diameter greater than the second diameter.

14. The apparatus of claim 6 wherein the filter region has a contracted state suitable for transluminal delivery, and the distal region has a length that is greater than a length of the filter element in the contracted state.

15. The apparatus of claim 6 wherein the filter region has a contracted state suitable for transluminal delivery, the apparatus further comprising a flexible catheter having a lumen and a push tube disposed in the lumen, the push tube having a guide wire lumen for accepting the guide wire, and wherein the lumen is sized to accept the filter element in the contracted state.

16. Apparatus for filtering emboli during treatment of occlusive disease in a vessel, the apparatus comprising:

a guide wire having a first diameter and a distal region having a second diameter greater than the first diameter;

a filter element having a sac coupled to a capture ring, the capture ring having an aperture greater than the first diameter but smaller than the second diameter,

wherein the filter element is disposed on the guide wire and the guide wire extends through the aperture with the distal region disposed distally of the capture ring, so that when the filter element is deployed in the vessel, rotation or distal translation of the guide wire does not displace the filter element, but retraction of the guide wire in a proximal direction causes the distal region to abut against the capture ring.

17. The apparatus of claim 16 wherein the filter element further comprises a plurality of self-expanding struts coupled between the sac and the capture ring.

18. The apparatus of claim 17 wherein the filter element further comprises an elastomeric cone affixed to a distal portion of the sac.

19. The apparatus of claim 16 wherein the filter element further comprises a cylindrical sleeve coupled between the plurality of self-expanding struts and the capture ring.

20. The apparatus of claim 16 wherein the filter element further comprises a distal ring coupled to the sac, the distal ring having a bore with a diameter greater than the second diameter.

21. A method of filtering emboli from blood flowing through a vessel, the method comprising:

providing a guide wire having a distal region including a stop, and a filter element having a capture ring disposed for translation on the guide wire proximal of the stop;

transluminally inserting the guide wire and filter element into a vessel;

deploying the filter element to engage a wall of the vessel, the filter element filtering emboli out of blood flowing through the vessel;

advancing a treatment device along the guide wire to treat a portion of the vessel proximal to the location of the filter element, rotation or distal translation of the guide wire relative to the filter element imparted by the treatment device not displacing the filter element.

22. The method of claim 21 further comprising a step of, after use of the treatment device is completed, pulling the guide wire proximally so that the stop engages the capture ring and causes the filter element to return to the contracted state.

23. The method of claim 21 further comprising:

providing a delivery sheath; and

compressing the filter element to a contracted state to insert the filter element within the delivery sheath.

24. The method of claim 21 wherein the filter element comprises an expandable sac, and deploying the filter element comprises expanding the expandable sac so that a perimeter of the expandable sac contacts the wall of the vessel.

25. The method of claim 24 wherein the filter element further comprises a cylindrical sleeve and deploying the filter element further comprises expanding the cylindrical sleeve against the wall of the vessel.

26. The method of claim 21 further comprising providing a catheter having a lumen, and pulling the guide wire proximally causes the filter element to become retracted within the lumen.