Method and composition for rewetting contact lenses and relieving eye dryness

• US 6,180,093 B1
• Filed: 08/21/1997
• Issued: 01/30/2001
• Est. Priority Date: 09/20/1996
• Status: Expired due to Fees

• Current Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Original Assignee: Bausch & Lomb Incorporated (Bausch Health Cos., Inc.)
• Inventors: Sanzgiri, Yeshwant, Moran, Irene, De, Nimai C.
• Primary Examiner(s): Page, Thurman K.
• Assistant Examiner(s): WARE, TODD
• Application Number:
  US08/915,708
• Time in Patent Office: 1,258 Days
• Field of Search: 424/78.04, 514/912, 514/915, 514/635
• US Class Current: 424/78.04
• CPC Class Codes: A61K 9/0048 Eye, e.g. artificial tears
• CPC Class Codes: A61P 27/04 Artificial tears; Irrigation solutions

Abstract

The present invention is directed to a lubricant for contact lenses or dry eye or to provide relief from eye irritation. In particular, the composition contains a biguanide preservative in combination with polyvinylpyrollidone. An ophthalmic solution containing such a combination of components can be applied, in the form of droplets, to the eye or to contact lens in the eye. In one embodiment of the invention, the composition is used as a universal lubricant, meaning that the same solution can be used with or without contact lenses, depending on the needs of the user, whether in the context of a contact-lens care or general eye care.

Claims

1. An aqueous solution for treating dry eye, consisting of:

(a) at least one antimicrobial agent, wherein the antimicrobial agent includes a biguanide antimicrobial agent;

(b) at least one polyvinylpyrrolidone polymer;

(c) at least one buffering agent;

(d) at least one sequestering agent;

(e) at least one tonicity agent and/or pH adjusting agent;

(f) water; and

(g) optionally, at least one surfactant.