Bioenergetic data collection apparatus

• US 6,188,470 B1
• Filed: 06/30/1999
• Issued: 02/13/2001
• Est. Priority Date: 01/04/1996
• Status: Expired due to Fees

• Current Assignee: Larkace Pty., Ltd.
• Original Assignee: Larkace Pty., Ltd.
• Inventors: Grace, Robert John
• Primary Examiner(s): Font, Frank G.
• Assistant Examiner(s): Nguyen, Sang H.
• Application Number:
  US09/331,993
• Time in Patent Office: 594 Days
• Field of Search: 356/39, 356/41, 356/42, 600/556, 600/523, 600/323, 600/13-15, 600/333-336, 600/326, 600/477, 600/478
• US Class Current: 356/39
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/411 Detecting or monitoring allergy or intolerance reactions to an allergenic agent or substance

Abstract

A Bioenergetic Data Collection Apparatus utilizing a modified oximeter (1) to collect signals characteristic of blood flow in terminal tissue, such as a finger tip (12). A processing means (7) in signal connection with the modified oximeter (1) receives and analyzes the signals to produce pulse waveforms, or a pulse waveform sequence, that is displayed on a high resolution video display (5). An isolation means (8) is provided between the modified oximeter (1) and the processing means (7) to ensure no lethal voltages can threaten a patient. A variety of aids are provided to assist an appropriately skilled practitioner to make a prognosis from the displayed data. The tools include measurement of the ratio of heart activity to heart rest, variation in systolic pulse amplitude, variation in pulse shape, etc.

Claims

1. An apparatus for the collection of bioenergetic data indicative of bioenergetic status of a body comprising:

a) optical monitoring means comprising detection means adapted to detect light and one or more light sources, the optical monitoring means being arranged and configured such that in use light from the one or more light sources passes through a part of the body of a patient, whereby the light is affected by the light characteristics of the part of the body and modulated by blood flowing within the part of the body, the optical monitoring means producing time-varying signals in response to the light detected by the detection means;

b) display means for displaying a trace;

c) processing means in signal connection with the optical monitoring means and the display means for processing the time-varying signals and for effecting display of the trace on the display means; and

d) wherein;

i) the optical monitoring means produce time-varying signals including high frequency components of the detected light, wherein said high frequency components are above the fundamental systolic pulse and diastolic pulse frequencies;

ii) the trace is derived from the time-varying signals, whereby the trace displays the high frequency components in the time-varying signals; and

iii) the high frequency components are indicative of bioenergetic data.

2. The apparatus of claim 1, further comprising an isolation means in signal connection with the optical monitoring means and the processing means, the isolation means providing electrical isolation between the monitoring means and the processing means.

3. The apparatus of claim 1, wherein the detection means is a photodiode, the photodiode producing the time-varying signals and being responsive to light received from said one or more light sources.

4. The apparatus of claim 1, wherein the optical monitoring detector comprises interface means, wherein the interface means performs preliminary processing of the time-varying signals from the detection means including converting analogue signals from the detection means to digital signals suitable for processing by the processing means.

5. The apparatus of claim 1, wherein the processing means is a microprocessor programmed to perform one or more algorithms to calculate bioenergetic data from the time-varying signals and to analyse the bioenergetic data to indicate bioenergetic status.

6. The apparatus of claim 1, wherein the bioenergetic data includes one or more measurable characteristics chosen from a list including:

ATP ramp angle, heart activity to rest ration, systolic pulse amplitude variation over time, systolic pulse amplitude to diastolic pulse amplitude ratio, and pulse shape variation.

7. The apparatus of claim 1, wherein the bioenergetic status of the body is indicated according to indicative functions chosen from a list including:

pulse rate, oxygen saturation in terminal tissue blood flow rate, elasticity of blood vessels, strength and regularity of heart beat, cardiac sufficiency, cardiac valve activity, cardiac or vascular metabolic abnormalities, cell energy change, latent hypertension, myocardium damage, cardiac inflammation, vascular inflammation, allergic response, immune system response changes, pulmonary function variation, cardiac function variation, intestinal bioenergetic reactions by analysis of the time-varying signals in conjunction with the bioenergetic data.

8. The apparatus of claim 1, wherein the display means is a high resolution video display adapted to display graphical and alphanumeric data.

9. The apparatus of claim 1, further comprising an allergy module in signal connection with the processing means, the allergy module comprising recording means adapted to record electrodermal readings in the form of before and after microvoltage changes occurring in response to known allergens, and analysis means adapted to provide signals characteristic of allergic reaction to known allergens by analysing said electrodermal readings and performing an objective computer based evaluation and assessment, wherein the processing means analyses the bioenergetic data and the signals characteristic of allergic reaction to indicate bioenergetic status.

10. The apparatus of claim 1, further comprising an EKG module in signal connection with the processing means, the EKG module adapted to produce signals characteristic of heart function, wherein the processing means analyses the bioenergetic data and the signals characteristic of heart function to indicate bioenergetic status.

11. The apparatus of claim 1, further comprising a pulse blood pressure module in signal connection with the processing means, the pulse blood pressure module adapted to provide signals characteristic of pulse pressure including diastolic, systolic and mean arterial pressure, wherein the processing means analyses the bioenergetic data and the signals characteristic of pulse pressure to indicate bioenergetic status.

12. An apparatus for the collection of bioenergetic data indicative of bioenergetic status of a body comprising:

a) optical monitoring means producing time-varying signals in response to light detected by detection means, wherein said light has passed through and been affected by the light characteristics of a part of the body and modulated by blood flowing within the part of the body, wherein the time-varying signals include high frequency components of the detected light and wherein the high frequency components are above the fundamental systolic pulse and diastolic pulse frequencies;

b) display means for displaying a trace;

c) processing means in signal communication with the optical monitoring means and the display means for processing the time-varying signals and for effecting display of the trace on the display means;

d) wherein;

i) the trace is derived from the time-varying signals;

ii) the display means are suitable for displaying the high frequency components in the time-varying signals;

iii) the high frequency components are indicative of bioenergetic data;

iv) the processing means extract bioenergetic data from the time-varying signals and determine bioenergetic status from the bioenergetic data,

v) the processing means analyses the time-varying signals to extract bioenergetic data including one or more of ATP ramp angle, heart activity to rest ration, systolic pulse amplitude variation over time, systolic pulse amplitude to diastolic pulse amplitude ratio, and pulse shape variation; and

vi) the apparatus facilitates determination of bioenergetic status of a body including one or more of pulse rate, oxygen saturation in terminal tissue blood flow rate, elasticity of blood vessels, strength and regularity of heart beat, cardiac sufficiency, cardiac valve activity, cardiac or vascular metabolic abnormalities, cell energy change, latent hypertension, myocardium damage, cardiac inflammation, vascular inflammation, allergic response, immune system response changes, pulmonary function variation, cardiac function variation, intestinal bioenergetic reactions by analysis of the time-varying signals in conjunction with the bioenergetic data.

13. A method of determining bioenergetic status of a body including the steps of:

transmitting visible and infrared radiation into terminal tissue;

measuring a time-varying signal proportional to visible and infrared radiation transmitted through the terminal tissue, wherein the time-varying signal includes high-frequency components of the measured radiation, and wherein the high frequency components are above the fundamental systolic pulse and diastolic pulse frequencies;

converting the time-varying signal to a digital signal;

passing the digital signal to a processing means;

processing the digital signal in the processing means to produce a displayable trace;

analysing the digital signal to obtain bioenergetic data;

displaying the displayable trace and bioenergetic data on a display means; and

analysing the trace and bioenergetic data to determine bioenergetic status.

14. The method of claim 13 further including the step of analysing the time varying signals to provide indicative measures of bioenergetic status.