Antimicrobial cationic peptides
First Claim
1. An isolated cationic peptide selected from the group consisting of:
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Abstract
A novel class of cationic peptides having antimicrobial activity is disclosed. These peptides can be encompassed by the formulas:
wherein:
m is 1 to 5;
n is 1 or 2;
o is 2 to 5;
r is 0 to 8;
u is 0 or 1;
X1 is Isoleucine, Leucine, Valine, Phenylalanine, Tyrosine, Tryptophan or Methionine;
X2 represents Tryptophan or Phenylalanine
X3 represents Arginine or Lysine;
X4 represents Tryptophan or Lysine; and
X5 represents Phenylalanine, Tryptophan, Arginine, Lysine, or Proline.
The invention also provides a method of producing a cationic peptide variant having antimicrobial activity.
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Citations
6 Claims
- 1. An isolated cationic peptide selected from the group consisting of:
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2. An isolated cationic peptide selected from the group consisting of:
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3. An isolated cationic peptide consisting of an amino acid sequence selected from the group consisting of:
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4. An isolated cationic peptide having an amino acid sequence selected from the group consisting of:
Specification