Endoscopic or fiberscopic imaging device using infrared fluorescence

• US 6,192,267 B1
• Filed: 11/27/1996
• Issued: 02/20/2001
• Est. Priority Date: 03/21/1994
• Status: Expired due to Fees

• Current Assignee: Gabriel Quentel, Scherninski, François
• Original Assignee: Gabriel Quentel, Scherninski, François
• Inventors: Scherninski, François, Quentel, Gabriel
• Primary Examiner(s): Lateef, Marvin M.
• Assistant Examiner(s): SHAW, SHAWNA JEANNINE
• Application Number:
  US08/704,677
• Time in Patent Office: 1,546 Days
• Field of Search: 128/664, 128/665, 128/654, 128/656, 128/633, 128/634, 600/473, 600/475, 600/476, 600/431, 600/433, 600/310, 600/342, 600/109, 600/160
• US Class Current: 600/473
• CPC Class Codes: A61B 5/0071 by measuring fluorescence emission
• CPC Class Codes: A61B 5/0086 using infrared radiation

Abstract

An angiography device including an endoscope designed to be inserted into a body cavity, a light source for emitting excitation light in a first wavelength range into the cavity, a digital camera for sensing an image of the body cavity in a second wave range that does not overlap the first wavelength range, and a screen for displaying the sense image, the first and second wavelength ranges lying in the infrared range.

Claims

1. An angiography device for inspecting a wall of a body cavity of a patient after the patient has been intravenously injected with a pharmaceutically acceptable dye, the dye being capable of emitting fluorescent light when excited by light having wavelengths which excite the dye, the device comprising:

a flexible duct of small section and having a free end for inserting in a body cavity to inspect a wall thereof;

excitation means for emitting light from said free end in a first range of wavelengths including wavelengths which excite the dye;

reception means for receiving, at said free end, a sensed image of an observed wall in a second wavelength range which includes wavelengths of fluorescent light emitted from the dye and which has substantially no overlap with the first wavelength range; and

display means for displaying the received image;

wherein the first wavelength range lies, at least in part, between about 766 nm and about 815 nm, and in which the second wavelength range lies, at least in part, between about 825 nm and about 840 nm; and

wherein the reception means comprise a digital sensor for directly transforming the sensed image into digital signals, and digital processing means for increasing definition, contrast, and brightness in the sensed image.

2. A device according to claim 1, in which the excitation means comprise a high power polychromatic light source, means for sequentially interrupting emission from the light source, an optical fiber for conveying the light emitted by the light source to the free end of the flexible duct, and a filter disposed to receive substantially all light that also passes along the optical fiber, said filter allowing substantially all of light in the first wavelength range to pass and absorbing substantially all light in the second wavelength range.

3. A device according to claim 2, wherein the means for sequentially interrupting the emission from the light source comprise a mask disposed upstream from the filter.

4. A device according to claim 2, wherein the light source comprises a flash lamp.

5. A device according to claim 2, wherein the light source comprises an adjustable power light source.

6. A device according to claim 2, wherein the filter comprises a removable filter.

7. A device according to claim 2, comprising at least three color filters, each of said at least three color filters comprising a separate passband in the visible range, and means for selectively or successively interposing each of said at least three color filters between the light source and the optical fiber.

8. A device according to claim 1, wherein the excitation means comprise a monochromatic laser source emitting infrared light, and an optical fiber for conveying the light emitted by the laser source to the free end of the flexible duct.

9. A device according to claim 1, wherein the excitation means comprises means for applying a narrow light beam on the wall to be observed, and comprises scanning means for moving the light beam so as to cause it to scan the wall to be observed.

10. A device according to claim 9, wherein the scanning means comprise a moving mirror pivotable about two mutually perpendicular axes, and control means for controlling pivoting of the mirror about both of said axes, the light beam reaching said mirror and being reflected thereby towards the wall to be observed.

11. A device according to claim 10, wherein the light beam passes through a fixed semi reflecting mirror before reaching the moving mirror, said fixed mirror reflecting, towards a digital detector cell sensitive in the infrared, substantially all light coming from the wall to be observed along a direction travelled by the light beam after it has been reflected on the moving mirror, a stop filter being interposed between the fixed mirror and the detector cell, said stop filter absorbing substantially all light in the first wavelength range and passing substantially all light in the second wavelength range.

12. A device according to claim 1, wherein the reception means comprise a digital camera responsive to infrared wavelengths and connected to the free end of the flexible duct by a reception optical fiber, said reception optical fiber conveying the light it receives at the free end of the flexible duct to the digital camera, a stop filter being disposed so that the light conveyed by the reception optical fiber passes therethrough, said stop filter absorbing substantially all light in the first wavelength range and passing substantially all light in the second wavelength range.

13. A device according claim 1, wherein the reception means comprise a digital camera that is sensitive to infrared wavelengths and that is disposed inside the flexible duct in the vicinity of the free end thereof, a stop filter being provided at said free end so that substantially all light flux received by the digital camera passes therethrough, said stop filter absorbing substantially all light in the first wavelength range and passing substantially all light in the second wavelength range.