Diagnostic membrane containing fatty acid sarcosinate surfactant for testing oral fluid
First Claim
1. A diagnostic test strip comprising a bibulous matrix having:
- a sample receiving zone for receiving a liquid specimen of oral fluid suspected of containing a particular analyte, reagent chemistry located for contact with the sample for detecting the particular analyte, and spaced from the sample receiving zone in a sample migration direction a detection zone for determining the presence of said particular analyte by providing a detectable change observable in the detection zone, wherein the sample migrates between the sample receiving zone and the detection zone, and wherein the sample receiving zone contains a sodium myristol sarcosinate surfactant.
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Abstract
A diagnostic test strip for determining the presence of a specified analyte in a fluid sample is described. The test strip has a test membrane sandwiched between two layers of a plastic sheath. The upper layer of the sheath has a sample well into which a liquid sample is placed. The test membrane has a sample receiving zone typically containing a buffer and a fatty acid sarcosinate. Adjacent to the sample receiving zone is a reagent zone containing reagent chemicals including gold colloid particles coated with antibodies to the specified analyte. In fluid connection with the reagent zone is a test zone containing immobilized molecules of the specified analyte. Preferably, in fluid connection with the test zone is a control zone containing an indicator that changes color when wetted by the sample and a liquid sink zone to absorb excess liquid in the sample.
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Citations
11 Claims
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1. A diagnostic test strip comprising a bibulous matrix having:
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a sample receiving zone for receiving a liquid specimen of oral fluid suspected of containing a particular analyte, reagent chemistry located for contact with the sample for detecting the particular analyte, and spaced from the sample receiving zone in a sample migration direction a detection zone for determining the presence of said particular analyte by providing a detectable change observable in the detection zone, wherein the sample migrates between the sample receiving zone and the detection zone, and wherein the sample receiving zone contains a sodium myristol sarcosinate surfactant. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
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Specification