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Polypeptide variants

  • US 6,194,551 B1
  • Filed: 03/31/1999
  • Issued: 02/27/2001
  • Est. Priority Date: 04/02/1998
  • Status: Expired due to Term
First Claim
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1. A variant of an antibody comprising a human IgG Fc region, which variant comprises an amino acid substitution at amino acid position 329, or at two or all of amino acid positions 329, 331 and 322 of the human IgG Fc region, where the numbering of the residues in the IgG Fc region is that of the EU index as in Kabat, and wherein the variant retains the ability to bind antigen.

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