Isoelastic suture material and device

• US 6,197,043 B1
• Filed: 08/18/1999
• Issued: 03/06/2001
• Est. Priority Date: 08/18/1999
• Status: Expired due to Term

• Current Assignee: James A. Davidson
• Original Assignee: James A. Davidson
• Inventors: Davidson, James A.
• Primary Examiner(s): Jackson, Gary
• Application Number:
  US09/376,227
• Time in Patent Office: 566 Days
• Field of Search: 606/228, 606/229, 606/230, 623/1, 623/11, 623/12, 424/443
• US Class Current: 606/228
• CPC Class Codes: A61B 17/06166 Sutures suture materials A61L17/00; manufacture of artificial threads D01D; treatment of threads D06M
• CPC Class Codes: A61B 2017/1107 for blood vessels
• CPC Class Codes: A61L 17/04 Non-resorbable materials
• CPC Class Codes: A61L 17/10 containing macromolecular materials

Abstract

A flexible, isoelastic polymer surgical suture and suture construct formed from a material selected from the group consisting of silicone, polyurethane, polyurethane copolymers, rubber, and other hemocompatible and biocompatible thermoplastic elastomers, wherein the suture and suture construct is formed from a single or multiple filament, the suture and suture construct having an elastic modulus between about 50 to 2000 psi, a tensile strength between about 500 to 50,000 psi, and a tensile elongation between about 100 to 1000 percent. In an alternate suture construct, the construct includes a base material and an inner core formed from a higher-strength fiber or group of fibers having a helical orientation. The low-modulus base material is selected from the group consisting of silicone, polyurethane, polyurethane copolymers, rubber, and other hemocompatible and biocompatible thermoplastic elastomers. In an alternate suture construct, the construct includes a base material and an inner core formed from a higher-strength fiber or group of fibers having a helical orientation. The inner core has an elastic modulus above about 2,000 psi, a tensile strength above about 10,000 psi, and a tensile elongation between about 1 to 80 percent.

Claims

1. A flexible, isoelastic polymer surgical suture and suture construct formed from a material selected from the group consisting of silicone, polyurethane, polyurethane copolymers, rubber, and hemocompatible and biocompatible thermoplastic elastomers, wherein the suture and suture construct is formed from at least a single filament, the suture and suture construct having an elastic modulus between about 50 to 2000 psi, a tensile strength between about 500 to 50,000 psi, and a tensile elongation between about 100 to 1000 percent.

2. The suture and suture construct of claim 1, wherein the filament is woven.

3. The suture and suture construct of claim 1, wherein the material is in a monofilament form and is selected from the group consisting of silicone, polyurethane and polyurethane copolymers, the suture and suture construct for use in suturing blood vessels.

4. The suture and suture construct of claim 1, wherein anti-thrombotic agents are incorporated into the polymeric material.

5. The suture and suture construct of claim 4, wherein anti-thrombotic agents are selected from the group consisting of heparin, hyaluronan, phosphorylcholine, platelet factors, peptides, and other proteins.

6. The suture and suture construct of claim 1, wherein anti-thrombotic agents coat the material forming the suture and suture construct.

7. The suture and suture construct of claim 6, wherein anti-thrombotic agents are selected from the group consisting of heparin, hyaluronan, phosphorylcholine, platelet factors, peptides, and other proteins.

8. The suture and suture construct of claim 1, wherein the filament is braided.

9. The suture and suture construct of claim 1, wherein the suture and suture construct is formed from multiple filaments.

10. The suture and suture construct of claim 9, wherein the multiple filaments are woven.

11. The suture and suture construct of claim 9, wherein the multiple filaments are braided.

12. A flexible, isoelastic polymer surgical suture construct consisting of:

a) a low-modulus base material selected from the group consisting of silicone, polyurethane, polyurethane copolymers, rubber, and hemocompatible and biocompatible thermoplastic elastomers;

b) an inner core formed from a single higher-strength fiber;

c) the base material having an elastic modulus between about 50 to 2000 psi, a tensile strength between about 500 to 50,000 psi, and a tensile elongation between about 100 to 1000 percent; and

d) the inner core having an elastic modulus above about 2,000 psi, a tensile strength above about 10,000 psi, and a tensile elongation between about 1 to 80 percent.

13. The suture construct of claim 12, wherein the inner core fiber is selected from the group consisting of polytetrafluorethylene, silk, polyester, nylon, polypropylene, polyethylene, and metal.

14. The suture construct of claim 12, wherein the inner core fibers woven.

15. The suture construct of claim 12, wherein the base material is impregnated with an anti-thrombotic agent.

16. The suture construct of claim 12, wherein the base material is coated with an anti-thrombotic agent.

17. The suture construct of claim 12, wherein the base material is impregnated and coated with an anti-thrombotic agent.

18. The suture construct of claim 12, wherein the inner core is formed from a group of fibers having a helical orientation.

19. The suture construct of claim 12, wherein the inner core fibers are braided.